4-Amino-1-Boc-piperidine
- CAS No.
- 87120-72-7
- Chemical Name:
- 4-Amino-1-Boc-piperidine
- Synonyms
- TERT-BUTYL 4-AMINOPIPERIDINE-1-CARBOXYLATE;1-BOC-4-AMINOPIPERIDINE;N-BOC-4-AMINOPIPERIDINE;1-BUTYLOXYCARBONYL-4-AMINO-PIPERIDINE;4-Amino-piperidine-1-carboxylic acid t-butyl ester;4-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;EOS-61525;1-BOC-4-AMI;BOC-PIP(4-NH2);BUTTPARK 90\06-10
- CBNumber:
- CB8758747
- Molecular Formula:
- C10H20N2O2
- Molecular Weight:
- 200.28
- MDL Number:
- MFCD01076201
- MOL File:
- 87120-72-7.mol
- MSDS File:
- SDS
Melting point | 50°C |
---|---|
Boiling point | 80/0.037mm |
Density | 1.041±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
pka | 10.10±0.20(Predicted) |
form | Crystalline Powder, Crystals and/or Chunks |
color | White to pale yellow to beige |
Water Solubility | Insoluble in water. |
Sensitive | Air Sensitive |
InChI | InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-8(11)5-7-12/h8H,4-7,11H2,1-3H3 |
InChIKey | LZRDHSFPLUWYAX-UHFFFAOYSA-N |
SMILES | N1(C(OC(C)(C)C)=O)CCC(N)CC1 |
CAS DataBase Reference | 87120-72-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H302-H315-H318-H335 | |||||||||
Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-37/38-41-36/37/38-20/21/22-20/21/2236/37/38 | |||||||||
Safety Statements | 26-36/37/39-22-222636/37/39 | |||||||||
RIDADR | 3259 | |||||||||
WGK Germany | 2 | |||||||||
F | 10-34 | |||||||||
Hazard Note | Irritant | |||||||||
TSCA | N | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | Ⅲ | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
4-Amino-1-Boc-piperidine price More Price(56)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 640042 | 4-Amino-1-Boc-piperidine 97% | 87120-72-7 | 1g | $42.7 | 2024-03-01 | Buy |
Sigma-Aldrich | 640042 | 4-Amino-1-Boc-piperidine 97% | 87120-72-7 | 5g | $144 | 2024-03-01 | Buy |
TCI Chemical | A2045 | 4-Amino-1-tert-butoxycarbonylpiperidine >97.0%(T) | 87120-72-7 | 1g | $44 | 2024-03-01 | Buy |
TCI Chemical | A2045 | 4-Amino-1-tert-butoxycarbonylpiperidine >97.0%(T) | 87120-72-7 | 5g | $125 | 2024-03-01 | Buy |
Alfa Aesar | H30779 | 4-Amino-1-Boc-piperidine, 97% | 87120-72-7 | 1g | $53.65 | 2024-03-01 | Buy |
4-Amino-1-Boc-piperidine Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Amino-1-Boc-piperidine is a potent inhibitor of the CCR5 receptor. It is an x-ray crystal structure with a hydroxide solution that inhibits the growth of cancer cells. The inhibitor binding site for 4-Amino-1-Boc-piperidine was determined to be the CCR5 receptor, which is located on the surface of hematopoietic cells. The compound has been shown to inhibit human T lymphocyte proliferation in vitro and inhibit HIV replication in infected patients. 4-Amino-1-Boc-piperidine is able to inhibit the growth of cancer cells by blocking the production of cytokines, such as interleukin 2, that are needed for cell division and growth.
Uses
4-Amino-1-Boc-piperidine is a chemical reagent used in the preparation of pharmaceutical compounds. Used in the synthesis of bromodomain inhibitors as well as HepG2 cell cycle inhibitors used in anti-tumor therapy. Also employed in a microwave-assisted solid-phase synthesis of N-substituted piperidines via direct annulation of primary amines with resin-bound dimesylates.
Application
4-Amino-1-Boc-piperidine is a pharmaceutical intermediate is applied in the treatment of anti-tumor and other drugs. It is an important fine chemical intermediate and has a wide range of uses in the pharmaceutical industry.
4-Amino-1-Boc-piperidine Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 | alice@jndxj.com | China | 303 | 58 |
Shanghai Hengmao New Materials Technology CO., LIMITED | +86-0086-1773693-3208 +8617736933208 | 1137059254@qq.com | China | 9287 | 58 |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 20000 | 58 |
Wuhan Boyuan Import & Export Co., LTD | +86-15175982296 15175982296; | Mike@whby-chem.com | China | 983 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 | sales8@anhuiyiao.com | China | 253 | 58 |
Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 401 | 58 |
Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | hanson@sdhanjiang.com | China | 1527 | 58 |
Wuhan Xinhao Biotechnology Co., Ltd | +86-18120578002 +86-18120578002 | xinhao-6@xinhaoshengwu.com | China | 340 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
View Lastest Price from 4-Amino-1-Boc-piperidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-03-18 | 4-Amino-1-Boc-piperidine
87120-72-7
|
US $0.00 / kg | 1kg | 0.99 | 10T | Shandong Hanjiang Chemical Co., Ltd | ||
2024-03-18 | 4-Amino-1-Boc-piperidine
87120-72-7
|
US $10.00 / ASSAYS | 1ASSAYS | 99% | 10 tons | Dorne Chemical Technology co. LTD | ||
2024-03-13 | 4-Amino-1-Boc-piperidine
87120-72-7
|
US $0.00 / kg | 1kg | 98% | 500KG | Shanghai Joiny Pharmaceutical Co.,LTD |
- 4-Amino-1-Boc-piperidine
87120-72-7
- US $0.00 / kg
- 0.99
- Shandong Hanjiang Chemical Co., Ltd
- 4-Amino-1-Boc-piperidine
87120-72-7
- US $10.00 / ASSAYS
- 99%
- Dorne Chemical Technology co. LTD
- 4-Amino-1-Boc-piperidine
87120-72-7
- US $0.00 / kg
- 98%
- Shanghai Joiny Pharmaceutical Co.,LTD