ChemicalBook >> CAS DataBase List >>LY 344864
LY 344864
- CAS No.
- 186544-26-3
- Chemical Name:
- LY 344864
- Synonyms
- CS-660;Y344864;LY 344864;LY344864 HCL;LY344864;LY-344864;LY 344864 hydrochloride;(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide;Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-;(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride;N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
- CBNumber:
- CB8847478
- Molecular Formula:
- C21H22FN3O
- Molecular Weight:
- 351.42
- MDL Number:
- MFCD07772184
- MOL File:
- 186544-26-3.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:30:59
| Boiling point | 471.9±45.0 °C(Predicted) |
|---|---|
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | DMSO : ≥ 350 mg/mL (995.96 mM) |
| pka | 14.12±0.40(Predicted) |
| form | Powder |
| FDA UNII | L4WN6HH63L |
LY 344864 price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 2451 | LY344864 hydrochloride ≥99%(HPLC) | 186544-26-3 | 10 | $214 | 2021-12-16 | Buy |
| Tocris | 2451 | LY344864 hydrochloride ≥99%(HPLC) | 186544-26-3 | 50 | $884 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 71157 | LY-344864HCl | 186544-26-3 | 50mg | $1175 | 2021-12-16 | Buy |
| Matrix Scientific | 095130 | (R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride 95+% | 186544-26-3 | 1g | $4725 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 71157 | LY-344864HCl | 186544-26-3 | 10mg | $660 | 2021-12-16 | Buy |
LY 344864 Chemical Properties,Uses,Production
Uses
LY-344864 Hydrochloride is used as a selective 5-HTIF receptor agonist.
Biological Activity
Potent, selective 5-HT 1F receptor agonist (EC 50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (K i values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μ M for 5-HT 1F , 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 1E , 5-HT 2B , 5-HT 2C , 5-HT 2A and 5-HT 7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.
LY 344864 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
186544-26-3(LY 344864)Related Search:
LY 344864
LY 344864 hydrochloride
N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamidehydrochloride
(R)-N-[3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide
(R)-N-(3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl)-4-fluorobenzamide hydrochloride
LY344864 HCL
LY344864;LY-344864
CS-660
Y344864
Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-
migraines,Adrenergic Receptor,BBB penetration,Serotonin Receptor,inhibit,5-HT Receptor,LY-344864,Beta Receptor,Parkinson’s disease,LY 344864,Inhibitor,5-hydroxytryptamine Receptor,5-HT1F
186544-26-3
C21H22N3OFHCl
Inhibitors