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17alpha-Ethynyl-19-nortestosterone 17-heptanoate

17alpha-Ethynyl-19-nortestosterone 17-heptanoate
17alpha-Ethynyl-19-nortestosterone 17-heptanoate structure
CAS No.
3836-23-5
Chemical Name:
17alpha-Ethynyl-19-nortestosterone 17-heptanoate
Synonyms
ZK-5410;Norigest;SH-80393;Norlutin enanthate;17alpha-Ethynyl-19-n;norethindrone enantate;norethisterone enantate;Norethindrone Enanthate;NORETHISTERONE ENANTHATE;NORETHISTERONEOENANTHATE
CBNumber:
CB8849821
Molecular Formula:
C27H38O3
Formula Weight:
410.59
MOL File:
3836-23-5.mol

17alpha-Ethynyl-19-nortestosterone 17-heptanoate Properties

Melting point:
69.5°C
Boiling point:
470.54°C (rough estimate)
Density 
1.0736 (rough estimate)
refractive index 
1.4700 (estimate)
color 
Crystals from pet ether
CAS DataBase Reference
3836-23-5(CAS DataBase Reference)
FDA UNII
HY3S2K0J0F
SAFETY
  • Risk and Safety Statements
Toxicity TDLo vn-wmn: 4 mg/kg:EYE ADVPB4 8,103,72

17alpha-Ethynyl-19-nortestosterone 17-heptanoate Chemical Properties,Uses,Production

Originator

Norigest,Schering

Manufacturing Process

1 g 17-ethinyl-19-nor-testosteron was refluxed with 5 ml of enanthic acid anhydride on an oil bath at temperature 180°C 17 hours. Then the reaction mixture was distilled with water steam to the full disappearence of smell of enantic acid. After that it was washed with 2 N sodium hydroxide and finally with water to neutral, dried over sodium sulfate and evaporated to dryness. The oily residue was rubbed with some drops of methanol and stood at -8°C 24 hours to give the crystals of 3-endol diester; MP: 82°-84°C, 2 g of it was dissolved in 120 ml of methanol and heated with 1.2 ml concentrated hydrochloric acid. The partly saponified product was distilled with water steam to full disappearence of smell of enantic acid. The residue was mixed with ether, washed with 2 N sulfuric acid, 2 N sodium hydroxide, finally with water to neutral dried over sodium sulfate and evaporated to dryness. The residue was stirred with pentane and cooled for crystallization. Pure enanthate was crystallized after repeated solution in pentane. 17-α-Ethinyl-19nortestosterone enanthate had MP: 68°-71°C.

brand name

Binovum;Brevicon;Brevinor;Conceplan;Doryxas;Gesta plan;Lg 335;Menonorm;Miconor;Neocon;Nor 50;Norimin;Noristerat;Norlutate acetate;Nor-q-d;Norquentiel;Norquest fe;Novulon;Nur-isterate;Orlestrin;Ortho-novum;Ovcon-50;Ovismen;Ovysmen;Tri-norinyl.

Therapeutic Function

Progestin

World Health Organization (WHO)

Norethisterone enantate was introduced in 1978 for use as a longacting injectable contraceptive. Risk-benefit judgements differ significantly from country to country, having regard to differing national circumstances. Norethisterone enantate is, however, widely available and is included as a complementary drug in the WHO Model List of Essential Drugs. (Reference: (WHODI) WHO Drug Information, 2(1), , 1988)

Safety Profile

An experimental teratogen.Questionable carcinogen with experimental tumorigenicdata. Human systemic effects by intravenous route:increased intraocular pressure. Human reproductiveeffects by intramuscular route: menstrual cycle changes ordisorders, ch

17alpha-Ethynyl-19-nortestosterone 17-heptanoate Preparation Products And Raw materials

Raw materials

Preparation Products


17alpha-Ethynyl-19-nortestosterone 17-heptanoate Suppliers

Global( 117)Suppliers
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View Lastest Price from 17alpha-Ethynyl-19-nortestosterone 17-heptanoate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-04 Norethisterone Enanthate
3836-23-5
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-12-04 Norethisterone Enanthate
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-08-31 Norethisterone Enanthate
3836-23-5
US $10.00 / KG 1KG 99.99% 20 tons/month Wuhan Monad Medicine Tech Co.,LTD

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