ChemicalBook >> CAS DataBase List >>4-Methylumbelliferyl-beta-D-glucopyranoside
4-Methylumbelliferyl-beta-D-glucopyranoside
- CAS No.
- 18997-57-4
- Chemical Name:
- 4-Methylumbelliferyl-beta-D-glucopyranoside
- Synonyms
- MUD;MUG;MU-Glu;MUGGAL;MU-GAL;7-(B2;4-MU-GLU;GLC1-B-4MU;MUGLUCOSIDE;4-MU-β-Gluc
- CBNumber:
- CB8853266
- Molecular Formula:
- C16H18O8
- Molecular Weight:
- 338.31
- MDL Number:
- MFCD00063694
- MOL File:
- 18997-57-4.mol
Last updated:2023-09-04 15:51:00
| Melting point | 258-263 °C (dec.) |
|---|---|
| Boiling point | 394.46°C (rough estimate) |
| Density | 1.522 |
| refractive index | 1.4430 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 5 mg/ml; DMSO: 50 mg/ml |
| pka | 12.73±0.70(Predicted) |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble in DMF or water |
| λmax | 320nm(Buffer)(lit.) |
| BRN | 94672 |
| CAS DataBase Reference | 18997-57-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 3-10-21 |
| HS Code | 29389090 |
4-Methylumbelliferyl-beta-D-glucopyranoside price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 1g | $485 | 2024-03-01 | Buy |
| Sigma-Aldrich | M3633 | 4-Methylumbelliferyl β-D-glucopyranoside β-glucosidase substrate | 18997-57-4 | 5g | $1870 | 2024-03-01 | Buy |
| TCI Chemical | M3022 | 4-Methylumbelliferyl β-D-Glucopyranoside >98.0%(HPLC) | 18997-57-4 | 250mg | $26 | 2024-03-01 | Buy |
| TCI Chemical | M3022 | 4-Methylumbelliferyl β-D-Glucopyranoside >98.0%(HPLC) | 18997-57-4 | 1g | $73 | 2024-03-01 | Buy |
| Alfa Aesar | J66630 | 4-Methylumbelliferyl beta-D-glucopyranoside, 99% | 18997-57-4 | 1g | $135 | 2024-03-01 | Buy |
4-Methylumbelliferyl-beta-D-glucopyranoside Chemical Properties,Uses,Production
Description
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.
Chemical Properties
White Powder
Uses
4-Methylumbelliferyl β-D-glucopyranoside has been used as substrate:
- in glucosylceramidase β enzyme activity assay in lysosome-enriched fractions from primary hippocampal neurons
- in β-glucosidase assay during yeast fermentation
- to assay glucocerebrosidase 1 (GBA1)-related glucosidase activity in macrophage cell line (RAW)
Uses
A fluorogenic substrate in the assay of ?-glucosidase.Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15
Uses
A fluorogenic substrate in the assay of ?-glucosidase. Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15
Definition
ChEBI: A beta-D-glucoside having a 4-methylumbelliferyl substituent at the anomeric position.
Biochem/physiol Actions
4-Methylumbelliferyl β-D-glucopyranoside is a synthetic enzymatic substrate for glycosidase. It has been used as substrate for the β- glucosidase from enterococci.
Purification Methods
4-Methylumbellifer-7-yl--Dglucopyranoside crystallises as the half hydrate from hot H2O. [Constantzas & Kocourek Collect Czech Chem Commun 24 1099 1959, De Re et al. Ann Chim (Rome) 4 9 2089 1959, Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 III/IV 5152, 8 IV 433, 18/7 V 616.]
4-Methylumbelliferyl-beta-D-glucopyranoside Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 244)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 | info@fortunachem.com | China | 5988 | 58 |
View Lastest Price from 4-Methylumbelliferyl-beta-D-glucopyranoside manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-16 | 4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
|
US $0.00 / G | 10G | 98%min | 30kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-07-02 | 4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | 4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
|
US $1.00 / kg | 1kg | 98% | 100KG | Career Henan Chemical Co |
-
- 4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
- US $0.00 / G
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 4-Methylumbelliferyl-beta-D-glucopyranoside
18997-57-4
- US $1.00 / kg
- 98%
- Career Henan Chemical Co
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4-Methylumbelliferyl-beta-D-glucopyranoside,99%
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4-Methylumbelliferyl β-D-glucopyranoside ,98%
MU-Glu
3-MethyluMbelliferyl β-D-glucopyranoside
4-MethyluMbelliferyl-beta-D-glucopyranoside, 99% 500MG
4-MethyluMbelliferyl Glucopyranoside
4-Methylumbelliferyl β-D-glucopyranoside,MUD
4-Methyl-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one
4-methylumbelliferylglucoside
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MUD
MUGGAL
MUGLUCOSIDE
MUG
MU-GAL
MUGALACTOSIDE
METHYLUMBELLIFERYL-B-D-GALACTOPYRANOSIDE, 4-
METHYLUMBELLIFERYL-B-D-GLUCOPYRANOSIDE, 4-
GLC1-B-4MU
4-METHYLUMBELLIFERYL BETA-D-GLUCOSIDE
4-METHYLUMBELLIFERYL B-D-GALACTOPYRANOSIDE
4-METHYLUMBELLIFERYL-B-D-GALACTOSIDE
4-MU-BETA-D-GLC
4-MU-BETA-D-GAL
7-HYDROXY-4-METHYLCUMARIN-BETA-D-GALACTOPYRANOSID
7-HYDROXY-4-METHYLCUMARIN-BETA-D-GLUCOPYRANOSID
4-METHYLUMBELLIFERYL-B-D-GLUCOPYRANOSIDE
4-METHYLUMBELLIFERYL-B-D-GLUCOSIDE
4'-METHYLUMBELLIFERYL-BETA-D-GLUCOPYRANOSIDE
4-METHYLUMBELLIFERYL-BETA-D-GLUCOPYRANOSIDE
3-Methylumbelliferyl
7-(beta-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
4-METHYLUMBELLIFERYL-SS-D-GLUCOPYRANOSIDE
4-Methylumbelliferyl β-D-glucopyranosid
4-Methylumbelliferyl-beta-D-glucoside *CAS 18997-57-4*
4-methyl-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-4-methyl-
4-Methylumbelliferyl β-D-glucopyranoside
4-Methylumbelliferyl-beta-D-glucopyranoside USP/EP/BP
4-Methylumbelliferyl β-D-Glucoside
7-(B2
-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
4-Methylumbellifery-β-D-glucopyranoside
4-Methylumbelliferyl-β-D- Glucopyranoside extrapure
2H-1-Benzopyran-2-one,7-(b-D-glucopyranosyloxy)-4-methyl-
4-MU-GLU
4-MU-β-Gluc
fluorogenic,substrate,4 Methylumbelliferyl β D Glucopyranoside,Inhibitor,chromogenic,4MethylumbelliferylβDGlucopyranoside,inhibit,4-methylumbelliferyl,fluorescent
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-4-methyl-
4-Methylumbelliferone- β- D-glucoside