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Isopropylamine

Isopropylamine
Isopropylamine structure
CAS No.
75-31-0
Chemical Name:
Isopropylamine
Synonyms
MIPA;MIPA-70;nsc62775;iso-C3H7NH2;i-Propylamin;Isopropylamin;2-Aminopropan;2-Propylamine;2-Propanamine;sopropylamine
CBNumber:
CB8854223
Molecular Formula:
C3H9N
Formula Weight:
59.11
MOL File:
75-31-0.mol

Isopropylamine Properties

Melting point:
-101 °C
Boiling point:
32-35 °C 33-34 °C (lit.)
Density 
0.688 g/mL at 20 °C (lit.)
vapor density 
2.04 (vs air)
vapor pressure 
9.2 psi ( 20 °C)
refractive index 
n20/D 1.374(lit.)
FEMA 
4238 | ISOPROPYLAMINE
Flash point:
−26 °F
storage temp. 
2-8°C
solubility 
1000g/l
form 
Crystalline Powder, Needles or Crystals
pka
10.63(at 25℃)
color 
APHA: ≤50
PH
13 (700g/l, H2O, 20℃)
Odor
Strong ammoniacal; pungent, irritating, typical amine.
Odor Threshold
0.025ppm
explosive limit
2-10.4%(V)
Water Solubility 
soluble
Sensitive 
Air Sensitive
JECFA Number
1581
Merck 
14,5209
BRN 
605259
Exposure limits
TLV-TWA 5 ppm (~12 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 10 ppm(~24 mg/m3) (ACGIH); IDLH 4000 ppm (NIOSH).
Stability:
Stable. Extremely flammable - note low boiling point and low flash point. Readily forms explosive mixtures with air. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, perchloryl fluoride.
CAS DataBase Reference
75-31-0(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
ISOPROPYLAMINE
EWG's Food Scores
3-5
FDA UNII
P8W26T4MTD
NIST Chemistry Reference
2-Propanamine(75-31-0)
EPA Substance Registry System
Isopropylamine (75-31-0)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS05,GHS06,GHS07
Signal word  Danger
Hazard statements  H315-H319-H224-H301+H311+H331-H314-H335
Precautionary statements  P405-P501a-P210-P261-P280-P303+P361+P353-P305+P351+P338-P370+P378
Hazard Codes  F+,Xi,T
Risk Statements  12-36/37/38-37-35-25-20/21
Safety Statements  16-26-29-45-36/37/39
RIDADR  UN 1221 3/PG 1
WGK Germany  1
RTECS  NT8400000
34
Autoignition Temperature 755 °F
TSCA  Yes
HS Code  2921 19 99
HazardClass  3
PackingGroup  I
Toxicity LD50 orally in rats: 820 mg/kg (Smyth)
NFPA 704
4
3 0

Isopropylamine price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 471291 Isopropylamine ≥99.5% 75-31-0 1l $40.7 2021-03-22 Buy
Sigma-Aldrich 8.07476 Isopropylamine for synthesis 75-31-0 1 L $44.58 2021-03-22 Buy
Sigma-Aldrich 8.07476 Isopropylamine for synthesis 75-31-0 100 mL $25.53 2021-03-22 Buy
Sigma-Aldrich 471291 Isopropylamine ≥99.5% 75-31-0 2l $61.3 2021-03-22 Buy
Sigma-Aldrich 8.07476 Isopropylamine for synthesis 75-31-0 2.5 L $87.04 2021-03-22 Buy

Isopropylamine Chemical Properties,Uses,Production

Description

Isopropylamine (propan-2-amine, IUPAC) is a colorless, volatile liquid. It is highly flammable, with a flammable range of 2%–10.4% in air. Boiling point is 93°F (33°C), flash point is ?15°F (?26°C), and ignition temperature is 756°F (402°C).
It is miscible with water, with a specific gravity of 0.69, which is lighter than water. Vapor density is 2.04, which is heavier than air. In addition to flammability, isopropylamine is a strong irritant to tissue and has a TLV of 5 ppm in air. The four-digit UN identification number is 1221. The NFPA 704 designation for isopropylamine is health 3, flammability 4, and reactivity 0. Primary uses for isopropylamine are pharmaceuticals, dyes, insecticides, and as a dehairing agent.

Chemical Properties

Isopropylamine is a colorless, flammable liquid. Isopropylamine is miscible with water, alcohol, and ether.The odor threshold reportedly ranges from 0.21 to 0.70 ppm; the pungent, ammoniacal odor becomes irritating at 24mg/m3 (110).

Physical properties

Colorless liquid with a penetrating, ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 500 μg/m3 (210 ppbv) and 1.7 mg/m3 (700 ppbv), respectively (Hellman and Small, 1974). An odor threshold concentration of 25 ppbv was reported by Nagata and Takeuchi (1990).

Occurrence

Not reported found in natu

Uses

Isopropylamine is used as a dehairing agentand as an intermediate in the preparation ofmany organics.

Uses

Isopropylamine is an organic compound is a widely used for the synthesis of pharmaceutical and agricultural goods such as glyphosphate herbicides and as an additive for petroleum industry.

Uses

Solvent, intermediate in synthesis of rubber accelerators, pharmaceuticals, dyes, insecticides, bactericides, textile specialties, and surface-active agents, dehairing agent, solubilizer for 2,4-D acid.

Production Methods

Isopropylamine can be produced from the corresponding alcohol by reacting with ammonia in the presence of a dehydrating catalyst, or from the chloride by reacting with ammonia under pressure. It is also reported that this amine can be produced from acetone and ammonia or from the acetone oxime (HSDB 1989).

Definition

ChEBI: A member of the class of alkylamines that is propane carrying an amino group at position 2.

Aroma threshold values

High strength odor; fishy type; recommend smelling in a 0.10% solution or less.

General Description

A clear colorless liquid with an ammonia-like odor. Flash point -35°F. Boiling point 90°F. Less dense than water Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a solvent and to make other chemicals.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

Isopropylamine is a colorless, alkaline liquid, very volatile, moderately toxic, highly flammable. Dangerous fire hazard when exposed to heat, flame, sparks, or strong oxidizers. When heated to decomposition Isopropylamine emits toxic fumes of oxides of nitrogen [M. K.]. A mixture of Isopropylamine and perchloryl fluoride resulted in an uncontrolled oxidation and/or explosion, [J. Org. Chem., 1980, 45, 4036]. The reaction of 1-chloro-2,3-epoxypropane and the amine and most probably other nitrogen bases, yields a violent exotherm, [Chem. & Ind., 1971, 994].

Hazard

Highly flammable, dangerous fire risk. Strong irritant to tissue.

Health Hazard

Isopropylamine is a strong irritant to theeyes, skin, and respiratory system. A shortexposure to 10–20 ppm can cause irritationof the nose and throat in humans (Procturand Hughes 1978). Prolonged exposure tohigh concentrations may lead to pulmonaryedema. Skin contact can cause dermatitisand skin burns. Exposure to 8000 ppm for4 hours was lethal to rats.
LD50 value, oral (mice): 2200 mg/kg.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Industrial uses

Isopropylamine can be used as a dehairing agent and as a solvent. It also finds use as an intermediate in the production of insecticides, herbicides and bactericides and in the production of pharmaceuticals, dyes and rubber accelerators (HSDB 1989).

Environmental Fate

Photolytic. Low et al. (1991) reported that the photooxidation of aqueous primary amine solutions by UV light in the presence of titanium dioxide resulted in the formation of ammonium and nitrate ions.
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987). Forms water-soluble salts with acids.

Metabolism

One would expect isopropylamine to be readily absorbed from the gut and respiratory tract. Shorter chain aliphatic amines such as isopropylamine also are efficiently absorbed through the skin (Beard and Noe 1981). When administered intravenously, isopropylamine distributed rapidly into tissue compartments with tissue/plasma ratios ranging from 1.8 in the atrium to 16.7 in the renal medulla (Privitera et al 1982). During the elimination phase, a half-life of 146 min was observed in plasma. There do not appear to be any definitive metabolic studies with this compound, however through a comparison with other substrates, one might expect oxidation to acetone and ammonia through the action of monoamine oxidase (Tipton 1980).

Isopropylamine Preparation Products And Raw materials

Raw materials

Preparation Products


Isopropylamine Suppliers

Global( 254)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2941 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5902 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213
+86 15821988213 info@longyupharma.com China 2473 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47498 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29864 58
Zhengzhou Alfa Chemical Co.,Ltd
+8613343822234 +86-0371-55052911
sales5@alfachem.cn;sales9@alfachem.cn;sale1@alfachem.cn China 11995 58

View Lastest Price from Isopropylamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-02 Isopropylamine
75-31-0
US $20.00 / Kg/Drum 25Kg/Drum 99.99% 1 ton per week Wuhan Mulei New Material Technology Co. Ltd
2021-11-08 Isopropylamine
75-31-0
US $5.00 / KG 1KG 99% 20 Tons Wuhan wingroup Pharmaceutical Co., Ltd
2020-08-27 2-nitroimidazole
75-31-0
US $12.00 / KG 1KG 99%min 5000 Kilogram/Kilograms per Month Hebei Runbin Biotechnology Co. LTD

Isopropylamine Spectrum


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