3,4-Dichloronitrobenzene
- CAS No.
- 99-54-7
- Chemical Name:
- 3,4-Dichloronitrobenzene
- Synonyms
- 1,2-DICHLORO-4-NITROBENZENE;3,4-DCNB;ai3-03268(usda);3,4-Dichloronitroben;3,4-dichlornitrobenzen;LABOTEST-BB LT00436959;3,4-Dichlornitrobenzene;3,4-DICHLORONITROBENZENE;3，4-Dichluoronitrobenzene;3,4-Dichlor-1-nitrobenzol
- CBNumber:
- CB8854768
- Molecular Formula:
- C6H3Cl2NO2
- Molecular Weight:
- 192
- MDL Number:
- MFCD00007207
- MOL File:
- 99-54-7.mol
| Product description | Number | Pack Size | Price |
| 1,2-Dichloro-4-nitrobenzene 99% | D68800 | 100g | $33.5 |
| 3,4-Dichloronitrobenzene >97.0%(GC) | D0388 | 25g | $23 |
| 3,4-Dichloronitrobenzene >97.0%(GC) | D0388 | 500g | $86 |
| 1,2-Dichloro-4-nitrobenzene | D435535 | 100mg | $120 |
| 3,4-Dichloronitrobenzene 95% | JK330925 | 100g | $31 |
| More product size | |||
| Melting point | 39-41 °C(lit.) |
|---|---|
| Boiling point | 255-256 °C(lit.) |
| bulk density | 750kg/m3 |
| Density | 1.48 g/cm3 (55℃) |
| vapor pressure | 0.01 hPa (20 °C) |
| refractive index | 1.5929 (estimate) |
| Flash point | 255 °F |
| storage temp. | Store below +30°C. |
| solubility | 0.151g/l |
| form | Crystalline Mass |
| color | Yellow to brown |
| Water Solubility | 151 mg/L (20 ºC) |
| FreezingPoint | 30~31℃ |
| BRN | 1818163 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong bases. |
| CAS DataBase Reference | 99-54-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | IJT74JI7FS |
| NIST Chemistry Reference | Benzene, 1,2-dichloro-4-nitro-(99-54-7) |
| EPA Substance Registry System | 3,4-Dichloronitrobenzene (99-54-7) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317-H319 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-36-43-51/53 | |||||||||
| Safety Statements | 26-36/37-61-39-24/25 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CZ5250000 | |||||||||
| Autoignition Temperature | 420 °C | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29049085 | |||||||||
| Hazardous Substances Data | 99-54-7(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: 643 mg/kg LD50 dermal Rat > 2000 mg/kg | |||||||||
| NFPA 704 |
|
3,4-Dichloronitrobenzene Chemical Properties,Uses,Production
Chemical Properties
colourless to yellow crystals or beige powder
Uses
1,2-Dichloro-4-nitrobenzene is an intermediate in the synthesis of agrochemicals. Studies have been conducted to use 1,2-Dichloro-4-nitrobenzene as an organic intermediate for the synthetic preparation of ciprofloxacin (C482500).
Production Methods
Nitration of 1,2-dichlorobenzene with mixed acid at 35 – 60 ℃ results in a mixture of 3-nitro (10 %) and 4-nitro (90 %) isomers, which are separated by crystallization. A more expensive process (two stages from chlorobenzene) is based on chlorination of molten 4-chloronitrobenzene (90 – 100 ℃) by a process similar to that used for 3- chloronitrobenzene production. Chlorination has the advantage of giving a pure product, but it cannot be used if the isomeric 1,2-dichloro-3-nitrobenzene is also required.
Synthesis Reference(s)
The Journal of Organic Chemistry, 42, p. 3494, 1977 DOI: 10.1021/jo00442a009
General Description
Colorless crystals or light beige solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Can react vigorously with oxidizing materials.
Fire Hazard
3,4-Dichloronitrobenzene is combustible.
Flammability and Explosibility
Non flammable
Purification Methods
Crystallise it from absolute EtOH. [Beilstein 5 IV 726.]
3,4-Dichloronitrobenzene Preparation Products And Raw materials
Raw materials
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Preparation Products
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