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2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- structure

CAS No.: 2034181-36-5

Chemical Name:: 2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-

Synonyms: AMPA receptor modulator-2;2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-;6-(2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl)benzo[d]thiazol-2(3H)-one;6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1,3-benzothiazol-2-one;AMPA,AMPA receptor modulator-2,TARPγ,Ionotropic glutamate receptors,inhibit,Inhibitor,AMPA receptor modulator2,AMPA receptor modulator 2,iGluR

CBNumber:: CB88629180

Molecular Formula:: C15H6F6N4OS

Molecular Weight:: 404.29

MDL Number:

MOL File:: 2034181-36-5.mol

Last updated:2024-07-02 08:55:39

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2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Properties

Density	1.79±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 250 mg/mL (618.37 mM; Need ultrasonic)\|
pka	9.56±0.20(Predicted)
form	Solid
color	White to off-white
Water Solubility	Water : < 0.1 mg/mL (insoluble)

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0124040	AMPAreceptormodulator-2 99.20%	2034181-36-5	5mg	$380	2021-12-16	Buy
ChemScene	CS-0124040	AMPAreceptormodulator-2 99.20%	2034181-36-5	10mg	$600	2021-12-16	Buy
ChemScene	CS-0124040	AMPAreceptormodulator-2 99.20%	2034181-36-5	25mg	$1150	2021-12-16	Buy
ChemScene	CS-0124040	AMPAreceptormodulator-2 99.20%	2034181-36-5	50mg	$1800	2021-12-16	Buy
ChemScene	CS-0124040	AMPAreceptormodulator-2 99.20%	2034181-36-5	100mg	$2850	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-0124040	5mg	$380	Buy
CS-0124040	10mg	$600	Buy
CS-0124040	25mg	$1150	Buy
CS-0124040	50mg	$1800	Buy
CS-0124040	100mg	$2850	Buy

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Chemical Properties,Uses,Production

Biological Activity

AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50.

References

[1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460.

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Suppliers

Global( 10)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62163	58
Qi Qi hang Biotechnology Co., Ltd.	15870833005	2232044025@qq.com	China	8209	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11976	58
Wuhan Acumen Bio-Technology Co.,ltd	027-027-16602739303 16602739303	673003916@qq.com	China	2531	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	vip@med-life.cn	China	5012	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9268	58
Elucigen bio	13501719342	wayne.zheng@elucigenbio.com	China	4587	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Bide Pharmatech Ltd.	58
Qi Qi hang Biotechnology Co., Ltd.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58
Wuhan Acumen Bio-Technology Co.,ltd	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58
RD International Technology Co., Limited	58
Elucigen bio	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- Spectrum

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-(2034181-36-5)¹HNMR

2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- AMPA receptor modulator-2 AMPA,AMPA receptor modulator-2,TARPγ,Ionotropic glutamate receptors,inhibit,Inhibitor,AMPA receptor modulator2,AMPA receptor modulator 2,iGluR 6-(2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl)benzo[d]thiazol-2(3H)-one 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2,3-dihydro-1,3-benzothiazol-2-one 2034181-36-5 C15H6F6N4OS