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Melitracen hydrochloride

Melitracen hydrochloride structure

CAS No.: 10563-70-9

Chemical Name:: Melitracen hydrochloride

Synonyms: Adaptol;Thymeol;U-24973A;Melixeran;Trausabun;Adaptol-d6;Thymeol-d6;Melixeran-d6;Trausabun-d6;Melitracene-d6

CBNumber:: CB8874744

Molecular Formula:: C21H26ClN

Molecular Weight:: 327.89084

MDL Number:: MFCD00242905

MOL File:: 10563-70-9.mol

MSDS File:: SDS

Last updated:2023-09-20 08:34:21

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Melitracen hydrochloride Properties

Melting point	245-248°C
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in DMSO
form	Solid
color	White to Off-White
CAS DataBase Reference	10563-70-9(CAS DataBase Reference)
FDA UNII	J3448GKP5W

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Toxicity	LD50 i.v. in mice: 52 mg/kg (Petersen)

Melitracen hydrochloride price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M215500	MelitracenHydrochloride	10563-70-9	10mg	$155	2021-12-16	Buy
Usbiological	015892	Melitracen-d6 Hydrochloride	10563-70-9	1mg	$446	2021-12-16	Buy
Biosynth Carbosynth	FD71923	Melitracen hydrochloride	10563-70-9	5G	$450	2021-12-16	Buy
Biosynth Carbosynth	FD71923	Melitracen hydrochloride	10563-70-9	2g	$250	2021-12-16	Buy
Medical Isotopes, Inc.	18692	MelitracenHCl	10563-70-9	5mg	$950	2021-12-16	Buy

Product number	Packaging	Price	Buy
M215500	10mg	$155	Buy
015892	1mg	$446	Buy
FD71923	5G	$450	Buy
FD71923	2g	$250	Buy
18692	5mg	$950	Buy

Melitracen hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Originator

Trausabun,Lusofarma,W. Germany,1965

Uses

Antidepressant

Definition

ChEBI: Melitracen hydrochloride is a member of anthracenes.

Manufacturing Process

24 g of 2-o-benzoylphenylpropanol-2 (MP 116°C) were dissolved in 250 ml of anhydrous ether and the resulting solution was added dropwise while stirring to a suspension of 0.22 mol of dimethylaminopropylmagnesium chloride in 100 ml of ether. The reaction mixture was refluxed for one hour on a steam bath, and water and dilute hydrochloric acid were added until the reaction was pH 4-5. The aqueous phase was separated and 60 ml of concentrated aqueous ammonia were added. The mixture was extracted with ether, and the ether phase was separated, dried and evaporated in a steam bath. The residue was dissolved in hot petroleum ether and the solution left standing to cool for some time, whereupon 4-dimethylamino-1-phenyl-1-[2-(2-hydroxy-2- propyl)phenyl]-butanol-1 crystallized out as white crystals which were sucked off. After drying they melted at 88°C to 90°C.
10 g of this compound were cautiously dissolved in 50 ml of concentrated sulfuric acid under cooling and the mixture was kept at room temperature for 24 hours, whereupon the reaction mixture was poured into 200 g of finely crushed ice, and concentrated aqueous ammonia was added to about pH 9, whereupon the oil which separated out was extracted with ether. The ether phase was separated, dried and the ether evaporated on a steam bath. The residue was dissolved in 20 ml of acetone and the solution neutralized with a solution of dry hydrogen chloride in ether. The white crystals of 9-γdimethylaminopropylidene-10,10-dimethyl-9,10-dihydroanthracene hydrochloride which separated out was filtered off and dried. Yield 9 g. MP 245°C to 247°C.

Therapeutic Function

Antidepressant

Melitracen hydrochloride Preparation Products And Raw materials

Raw materials

Magnesium Sulfuric acid Hydrochloric acid 3-Chloro-1-(N,N-dimethyl)propylamine

Preparation Products

Melitracen hydrochloride Suppliers

Global( 169)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shandong ruiyue Biological Technology Co.，Ltd.	008615066100122（Lily wechat）	513075341@qq.com	CHINA	52	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 15319487004	1015@dideu.com	China	2263	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shandong ruiyue Biological Technology Co.，Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58

View Lastest Price from Melitracen hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-09-19	Melitracen hydrochloride 10563-70-9	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-08-02	Melitracen hydrochloride 10563-70-9	US $30.00 / kg	1kg	99%	1000tons	Henan Bao Enluo International TradeCo.，LTD
2022-10-18	Melitracen hydrochloride 10563-70-9	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

Melitracen hydrochloride
10563-70-9
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Melitracen hydrochloride
10563-70-9
US $30.00 / kg
99%
Henan Bao Enluo International TradeCo.，LTD

Melitracen hydrochloride
10563-70-9
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

Melitracen hydrochloride Spectrum

Melitracen hydrochloride(10563-70-9)¹HNMR

10563-70-9(Melitracen hydrochloride )Related Search:

1-AdaMantanethylaMine Dimethyl sulfoxide Melitracen Topotecan hydrochloride Isopropylamine

ETHANE Dimethyl ether Dimethyl fumarate Dimethyl sulfate Dimethyl carbonate

N,N-Dimethylformamide Diisopropylammonium dichloroacetate Dacthal 3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride (-)-2-[METHYLAMINO]-1-PHENYLPROPANE

Sibutramine hydrochloride Tramadol hydrochloride D/L-AMPHETAMINE HYDROCHLORIDE

1of4

MELITRACEN HYDROCHLORLD 1-Propanamine, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-, hydrochloride MELITRACEN HYDROCHLORID 3-[10,10-dimethyl-9(10H)-anthrylidene]-N,N-dimethylpropylamine hydrochloride Melitracen hydrochloride 3-(10,10-Dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine Hydrochloride 9-(3-Dimethylaminopropylidene)-10,10-dimethyl-9,10-dihydroanthracene Hydrochloride Adaptol Melixeran Thymeol Trausabun U-24973A 3-(10,10-Dimethyl-d6)-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine Hydrochloride 9-(3-Dimethylaminopropylidene)-10,10-(dimethyl-d6)-9,10-dihydroanthracene Hydrochloride Adaptol-d6 Melitracen-d6 Hydrochloride Melitracene-d6 Melixeran-d6 Thymeol-d6 Trausabun-d6 2-Melitracen hydrochloride 1-PropanaMine,3-(10,10-diMethyl-9(10H)-anthracenylidene)-N,N-diMethyl-, hydrochloride (1:1) Hydrochloride Melitracen Melitracen hydrochloride ###Melitracen Melitracen Hydrochlorlde 3-(10,10-dimethylanthracen-9(10H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride HYDROGEN MELITRACEN CHLORIDE 3-(10,10-dimethyl-9-anthracenylidene)-N,N-dimethyl-1-propanamine Melitracen Impurity C Thymeol hydrochloride Melitracen hydrochloride USP/EP/BP 10563-70-9 C21H20D6ClN C21H26NCl Isotope Labelled Compounds Antidepressant Isotope Labeled Compounds Amines Aromatics Intermediates & Fine Chemicals Pharmaceuticals