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Etidocaine

Etidocaine
Etidocaine structure
CAS No.
36637-18-0
Chemical Name:
Etidocaine
Synonyms
W-19053;Duranest;Etidocaine HCL;Etidocaine USP/EP/BP;N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanamide;ButanaMide, N-(2,6-diMethylphenyl)-2-(ethylpropylaMino)-
CBNumber:
CB8875271
Molecular Formula:
C17H28N2O
Formula Weight:
276.42
MOL File:
36637-18-0.mol

Etidocaine Properties

Boiling point:
389.7±30.0 °C(Predicted)
Density 
0.993±0.06 g/cm3(Predicted)
pka
14.18±0.70(Predicted)

Etidocaine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0008684 ETIDOCAINE 95.00% 36637-18-0 5MG $505.7 2021-12-16 Buy

Etidocaine Chemical Properties,Uses,Production

Originator

Duranest,Astra,US,1976

Uses

Anesthetic (local).

Definition

ChEBI: An amino acid amide in which 2-[ethyl(propyl)amino]butanoic acid and 2,6-dimethylaniline have combined to form the amide bond. Used as a local anaesthetic (amide caine), it has rapid onset and long action properties, similar to bupivacaine, and is given b injection during surgical procedures and during labour and delivery.

Manufacturing Process

α-(n-Propylamino)-n-butyro-2,6-xylidide(0.243 mol) and freshly distilled diethyl sulfate (1.6 mols were mixed in a flask equipped with reflux condenser, drying tube and stirrer. The mixture was stirred for 5 hours at 90°C. After cooling, water (110 ml) was added with stirring for 15 minutes followed by 4M HCl (110 ml). The solution was washed with ether (3 X 100 ml) and made alkaline with 7M NaOH to pH 10-11. The freed base was taken up in ether (3 X 100 ml); the extracts were dried over sodium sulfate, filtered and evaporated. The residue was dissolved in absolute ether (200 ml) and the hydrochloride prepared by addition of ethereal hydrogen chloride. The precipitate was filtered, washed with ether, and recrystallized twice from absolute ethanol/ether and from isopropanol/isopropylether; MP 203°C to 203.5°C; yield: 0.126 mol (52%). The starting material is prepared by reacting 2-bromobutyric acid with sulfonyl chloride to give the acid chloride. It is then reacted with 2,6-xylidine, then with potassium iodide followed by n-propylamine.

brand name

Duranest [as hydrochloride] (Astra).

Therapeutic Function

Local anesthetic

Etidocaine Preparation Products And Raw materials

Raw materials

Preparation Products


Etidocaine Suppliers

Global( 9)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
Dideu Industries Group Limited
029-88380327
Service@dideu.com CHINA 30014 58
Finetech Industry Limited
86 27 87465837
86 27 87772287 info@finetechnology-ind.com CHINA 9373 58
Hangzhou Sage Chemical Co., Ltd. 0571-86818502
Pls mail us for more information! info@sagechem.com China 10277 58
Finetech Industry Limited 19945049750
027-8777-2287 sales@finetechnology-ind.com; China 9376 58

View Lastest Price from Etidocaine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-07-09 Etidocaine USP/EP/BP
36637-18-0
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
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