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fenspiride

fenspiride
fenspiride structure
CAS No.
5053-06-5
Chemical Name:
fenspiride
Synonyms
DESP;FUBMN24;FUB-MN24;Fenspirid;fenspiride;Fenspiridum;Fenspiride-d5;fenspiride USP/EP/BP;8-phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one;Pharmaceutical intermediates BKEDBP BKEDBP bkedbp
CBNumber:
CB8875352
Molecular Formula:
C15H20N2O2
Formula Weight:
260.33
MOL File:
5053-06-5.mol

fenspiride Properties

Boiling point:
126-127 °C(Press: 2 Torr)
Density 
1.19±0.1 g/cm3(Predicted)
pka
12.44±0.20(Predicted)
FDA UNII
S983QC7HKM
ATC code
R03BX01,R03DX03

fenspiride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific S040 Fenspiride 5053-06-5 1g $384 2021-12-16 Buy
American Custom Chemicals Corporation RDL0006831 FENSPIRIDE-D5 95.00% 5053-06-5 5MG $500.31 2021-12-16 Buy
AK Scientific S040 Fenspiride 5053-06-5 5g $1051 2021-12-16 Buy
Medical Isotopes, Inc. D74913 Fenspiride-d5 5053-06-5 5 mg $1490 2021-12-16 Buy
J&W Pharmlab 60R0505 8-Phenethyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one 97% 5053-06-5 5g $3998 2021-12-16 Buy

fenspiride Chemical Properties,Uses,Production

Originator

Viarespan,Servier,France,1969

Uses

Bronchodilator;anti-adrenergic (β-receptor).

Manufacturing Process

A solution of 192 g of 1-phenethyl-4-hydroxy-4-aminomethyl piperidine in 800 cc of diethylcarbonate is heated for 2? hours to reflux at about 80°C in the presence of sodium methylate (prepared for immediate use from 2 g of sodium). After this time, the ethyl alcohol formed during the reaction is slowly distilled while the maximum temperature is reached. The excess ethyl carbonate is distilled under reduced pressure. A crystallized residue is then obtained, which is stirred with 400 cc of water and 400 cc of ether. The solution is filtered and 125 g (77.6%) of practically pure product melting at 232°C to 233°C, are obtained.
The starting material was prepared in a yield of 58% by reduction of the corresponding cyanohydrin. It in turn was prepared from 1-(2-phenylethyl)-4- piperidone and potassium cyanide to give the cyanohydrin which was reduced by lithium aluminum hydride.

Therapeutic Function

Bronchodilator

fenspiride Preparation Products And Raw materials

Raw materials

Preparation Products


fenspiride Suppliers

Global( 75)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hebei Miaobian Biotechnology Co., Ltd
17733850068 +8617733850068
Iglesia@cnhbmiaobian.com CHINA 906 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
Jinan Jianfeng Chemical Co., Ltd
15562555968
0531-88113608 info@pharmachemm.com CHINA 200 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Casorganics US Corp
+17326109938
sales@casorganics.com CHINA 175 58
Xi'an Kono chem co., Ltd.,
13289246953 029-86107037
info@konochemical.com CHINA 3000 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Hebei Xibaijie Biotechnology Co., Ltd.
0086 15232103582
aiana@hbxibaijie.com CHINA 636 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
+86-29-88380327 1012@dideu.com CHINA 3949 58

View Lastest Price from fenspiride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-17 Fenspiride
5053-06-5
US $200.00 / KG 1KG 99.9% 5 tons/month Shanxi Lianxu New Material Co., LTD
2021-11-25 fenspiride
5053-06-5
US $25.00 / KG 100g 99.99% 5ton/Month Hebei Yirun Sega Biological Technology Co. Ltd
2021-11-08 fenspiride
5053-06-5
US $10.00 / KG 500g 99% 2000MT/Month Wuhan wingroup Pharmaceutical Co., Ltd

5053-06-5(fenspiride)Related Search:


  • fenspiride
  • Fenspiridum
  • 8-phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
  • 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
  • DESP
  • Fenspirid
  • 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-
  • Fenspiride-d5
  • Pharmaceutical intermediates BKEDBP BKEDBP bkedbp
  • FUBMN24
  • FUB-MN24
  • fenspiride USP/EP/BP
  • 5053-06-5
  • 5053-6-5
  • 5053-38-7
  • 5053/6/5
  • Intermediate
  • medical intermediate
  • Pharm intermediate
  • organic
  • Pharmaceutical intermediates
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