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Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) structure
CAS No.
645400-44-8
Chemical Name:
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms
[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane;tert-butyl ((1S,3S)-3-aminocyclopentyl)carbamate;tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate;Carbamic acid, N-[(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester;Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
CBNumber:
CB91065960
Molecular Formula:
C10H20N2O2
Formula Weight:
200.28
MOL File:
645400-44-8.mol

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Properties

Boiling point:
304.2±31.0 °C(Predicted)
Density 
1.04±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
12.37±0.40(Predicted)

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T205890 tert-Butyl((1S,3S)-3-Aminocyclopentyl)carbamate 645400-44-8 100mg $350 2021-12-16 Buy
AK Scientific 7526DF Tert-Butyl((1S,3S)-3-aminocyclopentyl)carbamate 645400-44-8 5mg $158 2021-12-16 Buy
Biosynth Carbosynth FA158605 [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane 645400-44-8 25 mg $200 2021-12-16 Buy
Biosynth Carbosynth FA158605 [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane 645400-44-8 50 mg $300 2021-12-16 Buy
Biosynth Carbosynth FA158605 [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane 645400-44-8 5 mg $80 2021-12-16 Buy

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Uses,Production

Uses

tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate is used as a reactant in the synthesis of C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors.

Chemical Synthesis


A flask containing tert-butyl [(1S,3S)-3-aminocyclopentyl]carbamate (16.5 g, crude ~0.05 mol) and 1.7 g Pd-C (10% paste) in MeOH (300 mL) was exposed to a positive pressure of hydrogen gas (balloon) over weekend. The catalyst was filtered off and the mixture was concentrated to afford the title compound (9.5 g) as a thick colorless viscous oil. Tert-butyl [(1S,3S)-3-aminocyclopentyl]carbamate, Yield (9.5 g)

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products


Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Suppliers

Global( 36)Suppliers
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Chengdu Feibo Pharm Technology Co., Ltd
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Hangzhou Milestone Pharmtech Co., Ltd. 0571-82896630-
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  • Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
  • tert-butyl ((1S,3S)-3-aminocyclopentyl)carbamate
  • Carbamic acid, N-[(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester
  • tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate
  • [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane
  • 645400-44-8
  • N-BOC
  • CYCLOPENTANE
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