ChemicalBook >> CAS DataBase List >>Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
![Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Structure](CAS/GIF/645400-44-8.gif)
- CAS No.
- 645400-44-8
- Chemical Name:
- Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- tert-butyl ((1S,3S)-3-aminocyclopentyl)carbamate;tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate;[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane;1,1-Dimethylethyl N-[(1S,3S)-3-aminocyclopentyl]carbamate;Carbamic acid, N-[(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester;Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
- CBNumber:
- CB91065960
- Molecular Formula:
- C10H20N2O2
- Molecular Weight:
- 200.28
- MDL Number:
- MFCD11877864
- MOL File:
- 645400-44-8.mol
Last updated:2024-01-02 15:08:19
| Boiling point | 304.2±31.0 °C(Predicted) |
|---|---|
| Density | 1.04±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 12.37±0.40(Predicted) |
| InChI | InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-5-4-7(11)6-8/h7-8H,4-6,11H2,1-3H3,(H,12,13)/t7-,8-/m0/s1 |
| InChIKey | PGBVMVTUWHCOHX-YUMQZZPRSA-N |
| SMILES | C(OC(C)(C)C)(=O)N[C@H]1CC[C@H](N)C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2924297099 |
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T205890 | tert-Butyl((1S,3S)-3-Aminocyclopentyl)carbamate | 645400-44-8 | 100mg | $350 | 2021-12-16 | Buy |
| AK Scientific | 7526DF | Tert-Butyl((1S,3S)-3-aminocyclopentyl)carbamate | 645400-44-8 | 5mg | $158 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA158605 | [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane | 645400-44-8 | 25mg | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA158605 | [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane | 645400-44-8 | 50mg | $300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA158605 | [(1S,3S)-3-Amino-1-(boc-amino)cyclopentane | 645400-44-8 | 5mg | $80 | 2021-12-16 | Buy |
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Uses,Production
Uses
tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate is used as a reactant in the synthesis of C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors.
Synthesis
A flask containing tert-butyl [(1S,3S)-3-aminocyclopentyl]carbamate (16.5 g, crude ~0.05 mol) and 1.7 g Pd-C (10% paste) in MeOH (300 mL) was exposed to a positive pressure of hydrogen gas (balloon) over weekend. The catalyst was filtered off and the mixture was concentrated to afford the title compound (9.5 g) as a thick colorless viscous oil. Tert-butyl [(1S,3S)-3-aminocyclopentyl]carbamate, Yield (9.5 g)
Synthesis of Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) from Carbamic acid, [(1S,3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopentyl]-, phenylmethyl ester (9CI)
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Suppliers
Global( 80)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Guiding Bio-Tech. Co.,Ltd. | +86-519-519-86686860 +8618795626222 | ning@guiding-bio.com | China | 299 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
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| Chengdu Feibo Pharm Technology Co., Ltd | 15982321820 | abby@arkpharm.com | CHINA | 3279 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5658 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12755 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Carbamic acid, N-[(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester
[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane
tert-butyl ((1S,3S)-3-aminocyclopentyl)carbamate
tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate
1,1-Dimethylethyl N-[(1S,3S)-3-aminocyclopentyl]carbamate
645400-44-8
N-BOC
CYCLOPENTANE