ChemicalBook >> CAS DataBase List >>4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]-

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]-

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- structure

CAS No.: 129544-85-0

Chemical Name:: 4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]-

Synonyms: MIND4-19;3-benzylsulfanyl-5-phenoxymethyl-4-phenyl-1,2,4-triazole;3-(benzylthio)-5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazole;4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]-;Huntington's disease,4H 1,2,4 Triazole, 3 (phenoxymethyl) 4 phenyl 5 [(phenylmethyl)thio] ,4H1,2,4Triazole, 3(phenoxymethyl)4phenyl5[(phenylmethyl)thio],SIRT2,MIND4-19,Inhibitor,inhibit,Sirtuin

CBNumber:: CB910711779

Molecular Formula:: C22H19N3OS

Molecular Weight:: 373.47

MDL Number:

MOL File:: 129544-85-0.mol

Last updated:2023-09-04 15:50:00

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4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- Properties

Boiling point	591.4±60.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
storage temp.	4°C, protect from light
pka	0.75±0.10(Predicted)

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- Chemical Properties,Uses,Production

Biological Activity

MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease[1].

References

[1]. Quinti L, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. Cell Chem Biol. 2016 Jul 21;23(7):849-861.

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- Preparation Products And Raw materials

Raw materials

Preparation Products

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- Suppliers

Global( 9)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9838	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973 13515979683	sales@jamxmpharmatech.com	China	1080	58
Bide Pharmatech Ltd.	400-1647117 15221909166	product02@bidepharm.com	China	63720	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48467	58
RD International Technology Co., Limited	18024082417	market@ubiochem.com	China	9180	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Chaolan Chemical Technology Center	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
Bide Pharmatech Ltd.	58
TargetMol Chemicals Inc.	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
RD International Technology Co., Limited	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- Spectrum

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]-(129544-85-0)¹HNMR

4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- 3-(benzylthio)-5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazole Huntington's disease,4H 1,2,4 Triazole, 3 (phenoxymethyl) 4 phenyl 5 [(phenylmethyl)thio] ,4H1,2,4Triazole, 3(phenoxymethyl)4phenyl5[(phenylmethyl)thio],SIRT2,MIND4-19,Inhibitor,inhibit,Sirtuin MIND4-19 3-benzylsulfanyl-5-phenoxymethyl-4-phenyl-1,2,4-triazole 129544-85-0