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4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- structure

CAS No.: 785705-53-5

Chemical Name:: 4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-

Synonyms: WAY-350471;M4 mAChR agonist-1;1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide;4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-;inhibit,M4 mAChR agonist1?,Inhibitor,Muscarinic acetylcholine receptor,mAChR,M4 mAChR agonist-1,M4 mAChR agonist 1

CBNumber:: CB910783118

Molecular Formula:: C14H18N4OS

Molecular Weight:: 290.38

MDL Number:

MOL File:: 785705-53-5.mol

Last updated:2023-09-04 15:51:00

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4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- Properties

Boiling point	555.8±50.0 °C(Predicted)
Density	1.303±0.06 g/cm3(Predicted)
storage temp.	4°C, protect from light
solubility	DMSO : 20 mg/mL (68.88 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 70°C)
pka	16.25±0.20(Predicted)

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- Chemical Properties,Uses,Production

Biological Activity

M4 mAChR agonist-1 (compound 10a) is a potent M4 mAChR agonist with an EC50 >10 μM for human M4[1].

References

[1]. Wood MR, et al. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2016;26(13):3029-3033.

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9838	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973 13515979683	sales@jamxmpharmatech.com	China	1080	58
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TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48467	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Chaolan Chemical Technology Center	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
Xi'an Kaixin Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- Spectrum

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-(785705-53-5)¹HNMR

4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)- 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide M4 mAChR agonist-1 inhibit,M4 mAChR agonist1?,Inhibitor,Muscarinic acetylcholine receptor,mAChR,M4 mAChR agonist-1,M4 mAChR agonist 1 WAY-350471 785705-53-5