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Geclosporin

CAS No.
74436-00-3
Chemical Name:
Geclosporin
Synonyms
CS-2592;Geclosporin;cyclosporin G;Cyclosporine G;Cyclosporin G (9CI);Cyclosporin Impurity G;Cyclosporine Impurity G;Cyclosporine Impurity 7;Ring spore fungus element;Cyclosporin A, 7-L-norvaline-
CBNumber:
CB91117216
Molecular Formula:
C63H113N11O12
Molecular Weight:
1216.64
MDL Number:
MFCD00867600
MOL File:
74436-00-3.mol
Last updated:2023-04-23 13:52:06

Geclosporin Properties

Melting point 196-197°
alpha D20 -245° (c = 1.0 in chloroform); D20 -191° (c = 1.04 in methanol)
Boiling point 1297.8±65.0 °C(Predicted)
Density 1.013±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 13.32±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
InChIKey ZMKGDQSIRSGUDJ-LIAWPGETNA-N
EWG's Food Scores 1
FDA UNII UA3JNW70T9

Geclosporin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C990143 CyclosporinG 74436-00-3 5mg $570 2021-12-16 Buy
American Custom Chemicals Corporation API0011154 CYCLOSPORIN G 95.00% 74436-00-3 5MG $501.6 2021-12-16 Buy
Product number Packaging Price Buy
C990143 5mg $570 Buy
API0011154 5MG $501.6 Buy

Geclosporin Chemical Properties,Uses,Production

Uses

Cylclosporin G is a derivative of Cyclosporin A (C989900), an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cylclosporin G is a derivative of Cyclosporin A, an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Geclosporin Preparation Products And Raw materials

Raw materials

Preparation Products

Geclosporin Suppliers

Global( 58)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Excellent Biomedical Technology Co.,Ltd.
+86-0755-26050679 +86-15915472436 sale@ex-biotech.cn China 1031 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Shenzhen Excellent Biotech Co., Ltd.
13480692018 ramyan@ex-biotech.com CHINA 954 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
LUYUNJIA CHEMISTRY XIAMEN LIMITED
+86-592-5360779 +86-13055435203 China 5996 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Geclosporin (3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Nva-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) Cyclo(((2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl)-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl) Cyclosporin A, 7-L-norvaline- cyclosporin G Cyclosporine Impurity G Cyclosporin Impurity G CS-2592 Cyclosporine G/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] Cyclosporine G Ring spore fungus element Cyclosporin Impurity 7(Cyclosporin G) (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone Cyclosporine Impurity 7 Cyclosporin G (9CI) 74436-00-3 C63H113N11O12