3'-DEPHOSPHOCOENZYME A
- CAS No.
- 3633-59-8
- Chemical Name:
- 3'-DEPHOSPHOCOENZYME A
- Synonyms
- Dephospho-CoA;3'-dephospho-CoA;dephosphocoenzyme A;3'-DEPHOSPHOCOENZYME A;3'-O-dephosphono-coenzyme A;Coenzyme A, 3'-O-dephosphono-;3'-DEPHOSPHOCOENZYME A FREE ACID;3'-Dephosphocoenzyme A >=90% (HPLC);[5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-(2-sulfanylethylcarbamoyl)ethylcarbamoyl]propoxy]-phosphoryl]oxy-phosphinic acid
- CBNumber:
- CB9115282
- Molecular Formula:
- C21H35N7O13P2S
- Molecular Weight:
- 687.55
- MDL Number:
- MFCD00057010
- MOL File:
- 3633-59-8.mol
- MSDS File:
- SDS
3'-DEPHOSPHOCOENZYME A price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3385 | 3′-Dephosphocoenzyme A ≥90% (HPLC) | 3633-59-8 | 5mg | $218 | 2024-03-01 | Buy |
| Sigma-Aldrich | D3385 | 3′-Dephosphocoenzyme A ≥90% (HPLC) | 3633-59-8 | 25mg | $782 | 2024-03-01 | Buy |
| Cayman Chemical | 27390 | 3''-Dephosphocoenzyme A | 3633-59-8 | 1mg | $60 | 2024-03-01 | Buy |
| Cayman Chemical | 27390 | 3''-Dephosphocoenzyme A | 3633-59-8 | 10mg | $351 | 2024-03-01 | Buy |
| Cayman Chemical | 27390 | 3''-Dephosphocoenzyme A | 3633-59-8 | 5mg | $190 | 2024-03-01 | Buy |
3'-DEPHOSPHOCOENZYME A Chemical Properties,Uses,Production
Description
3''-Dephosphocoenzyme A is an intermediate in the biosynthesis of coenzyme A (CoA; Item Nos. 16147 | 21499 | 21722) from pantothenic acid (vitamin B5; ). It is phosphorylated by CoA synthase in humans to form CoA. 3''-Dephosphocoenzyme A can be used as a transcription initiator in the synthesis of CoA-RNA by in vitro transcription.
Uses
Dephosphocoenzyme A is the direct precursor of coenzyme A. It is used for the synthesis of coenzyme A by bifunctional CoA Synthase (CoASy, 4′-phosphopantetheine adenylyltransferase/dephospho-CoA kinase) which performs the transfer of the γ-phosphate of ATP to dephosphocoenzyme A.
Definition
ChEBI: An adenosine 5'-phosphate that is coenzyme A in which the phosphate group at position 3' has been replaced by a hydrogen atom. It is an intermediate metabolite in pantothenate and CoA biosynthesis
Biochem/physiol Actions
3′-Dephosphocoenzyme A (DepCoA), also called desphosphoCoA (dpCoA), is synthesized from 4-phosphopantetheine by the enzyme phosphopanthetheine adenylyltransferase. It is an intermediate in coenzyme A biosynthetic pathway. In the presence of dephospho-CoA kinase (CoaE), dephosphocoenzyme A is converted to coenzyme A. 3′-Dephosphocoenzyme shares adenosine-diphosphate substructure as like the purines and is a non-canonical nucleotide and is an initiator of transcription initiation. It is routinely used in in vitro transcription studies to initiate RNA synthesis.
3'-DEPHOSPHOCOENZYME A Preparation Products And Raw materials
Raw materials
Preparation Products
3'-DEPHOSPHOCOENZYME A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 10027 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18521732826; | market@aladdin-e.com | China | 25004 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29803 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 18621169109 | market03@meryer.com | China | 27996 | 58 |
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