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ANP 1-28, HUMAN

ANP 1-28, HUMAN structure

CAS No.: 89213-87-6

Chemical Name:: ANP 1-28, HUMAN

Synonyms: Carperitide;ATRIAL NATRIURETIC PEPTIDE HUMAN;SLRRSSCFGGRMDRIGAQSGLGCNSFRY;ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE);HANF;α-hANP;carperitida;ANP HUMAN, 1-28;ANP 1-28, HUMAN;ANF 1-28, HUMAN

CBNumber:: CB9116087

Molecular Formula:: C127H203N45O39S3

Molecular Weight:: 3080.44

MDL Number:: MFCD00076226

MOL File:: 89213-87-6.mol

Last updated:2024-03-27 11:49:37

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ANP 1-28, HUMAN Properties

Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Water: 1 mg/ml
form	A lyophilized powder
Sequence	H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH，(Disulfide bridge: Cys-Cys)
FDA UNII	GZ8FA500J0

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H361
Precautionary statements	P201-P202-P281-P308+P313-P405-P501

ANP 1-28, HUMAN price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	24539	Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt) ≥95%	89213-87-6	1mg	$384	2024-03-01	Buy
Tocris	1906	AtrialNatriureticFactor(1-28)(human,porcine)	89213-87-6	1	$367	2021-12-16	Buy
Biosynth Carbosynth	FA110233	Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	89213-87-6	500ug	$100	2021-12-16	Buy
Biosynth Carbosynth	FA110233	Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	89213-87-6	5mg	$602	2021-12-16	Buy
Biosynth Carbosynth	FA110233	Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond)	89213-87-6	10mg	$1047	2021-12-16	Buy

Product number	Packaging	Price	Buy
24539	1mg	$384	Buy
1906	1	$367	Buy
FA110233	500ug	$100	Buy
FA110233	5mg	$602	Buy
FA110233	10mg	$1047	Buy

ANP 1-28, HUMAN Chemical Properties,Uses,Production

Description

Carperitide is the α-human atrial natriuretic peptide (α-hANP) produced by recombinant technology. It was introduced in Japan as a treatment for acute congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the elevated left ventricular end-diastolic pressure and the index of myocardial oxygen consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was effective in improving hemodynamics and symptoms in 60% of patients with acute CHF. Carperitide was reported to be well tolerated with no significant adverse effects clinically. A beneficial effect on hemodynamics has been reported in chronic heart failure patients. Carperitide is also in clinical trials for maintenance of blood pressure during surgical operations.

Description

Atrial natriuretic peptide (ANP) is an endogenous peptide generated by proteolysis of prepro-ANP that is secreted by cardiomyocytes in the heart. It has effects on the renal and cardiovascular systems that decrease vasoconstriction, inhibit renin secretion, and increase sodium excretion. Human ANP binds to ANP receptors on cultured vascular smooth muscle cells (VSMCs) with a K_d value of approximately 1-2 nM and increases cGMP levels in a dose-dependent manner. It relaxes potassium-induced contraction of isolated canine renal arterial strips when used at concentrations of 10 and 100 ng/ml and dilates renal arteries in anesthetized dogs when used at doses ranging from 10 to 100 ng/kg. In a rat model of heart failure following experimental autoimmune myocarditis, human ANP, via osmotic mini pump for 28 days, decreases cardiomyocyte size as well as the amount of cardiac fibrosis and left ventricular remodeling. ANP (1-28) (human) is a 28 amino acid peptide corresponding to the human protein sequence.

Originator

Suntory (Japan)

Uses

Treatment of decompensated congestive heart failure.

Definition

ChEBI: Carperitide is a polypeptide.

brand name

Daiichi Suntory, Japan.

ANP 1-28, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

ANP 1-28, HUMAN Suppliers

Global( 125)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Xi'an Kono chem co., Ltd.,	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Cellmano Biotech Limited	58
Hebei Mojin Biotechnology Co., Ltd	58

View Lastest Price from ANP 1-28, HUMAN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-08	Atrial Natriuretic Factor (1-28) (human) acetate salt 89213-87-6	US $10.00 / kg	1kg	99%	1000kg	Nantong Guangyuan Chemicl Co,Ltd
2024-01-02	ANP 1-28, HUMAN 89213-87-6	US $80.00-800.00 / kg	10kg	0.99	20tons	Zibo Hangyu Biotechnology Development Co., Ltd
2023-09-18	ANP 1-28, HUMAN 89213-87-6	US $40.00-40.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.

Atrial Natriuretic Factor (1-28) (human) acetate salt
89213-87-6
US $10.00 / kg
99%
Nantong Guangyuan Chemicl Co,Ltd

ANP 1-28, HUMAN
89213-87-6
US $80.00-800.00 / kg
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

ANP 1-28, HUMAN
89213-87-6
US $40.00-40.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

89213-87-6(ANP 1-28, HUMAN)Related Search:

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PENTAGLYCINE H-ALA-ALA-ALA-TYR-OH H-ALA-ALA-ALA-ALA-ALA-ALA-OH AC-MET-NH2 N-ACETYL-ALA-ALA-ALA

3-[(3-AMINO-3-OXOPROPYL)DITHIO]PROPANAMIDE H-ALA-ALA-TYR-OH URODILATIN HUMAN AC-ILE-NHME H-ALA-ALA-ALA-ALA-OH

H-ARG-MET-NH2 ACETATE SALT GLY-ALA-TYR H-GLY-GLY-BETA-ALA-OH

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Atrial natriureticpeptide-28 (huMan) (9CI) Atrial Natriuretic Factor (1-28) (huMan) αhANF, Carperitide Carperitide Acetate ATRIAL NATRIURETIC PEPTIDE HUMAN, 1-28 ATRIAL NATRIURETIC PEPTIDE 1-28, HUMAN ATRIAL NATRIURETIC PEPTIDE (1-28), HUMAN, PORCINE ATRIAL NATRIURETIC FACTOR 1-28, HUMAN ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, CANINE) ANP, ALPHA-, HUMAN ANP HUMAN, 1-28 ANP (HUMAN, 1-28) (PORCINE, BOVINE, CANINE) ANP 1-28, HUMAN ANF 1-28, HUMAN ANF (1-28), HUMAN, PORCINE SLRRSSCFGGRMDRIGAQSGLGCNSFRY (DISULFIDE BRIDGE: 7-23) SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET(O)-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR [MET(O)12]-A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) [MET(O)12]-ANP (HUMAN, 1-28) atrial natriuretic factor (99-126) ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN, RECOMBINANT ALPHA-ANP [1-28] HUMAN, CANINE ALPHA-ANF (1-28), HUMAN ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN H-SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH (DISULFIDE BRIDGE: 7-23) HANF A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) (PORCINE, BOVINE, CANINE) ATRIAL NATRIURETIC PEPTIDE, ALPHA-, HUMAN Atrial natriuretic factor【human】 Atrial natriuretic peptide【porcine】 α-Atriopeptin【human】 α-hANP SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDE BRIDGE CYS7-CYS23. ahANF, Carperitide H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond) Carperitide / Carperitide Acetate L-Tyrosine, L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (7→23)-disulfi... Carperitide(ANP(1-28)/human) Carperitide impurity ANP 1-28, HUMAN USP/EP/BP Atrial Natriuretic Factor (1-28) (human), αhANF, Carperitide carperitida Carperitide Acetate, carperitida Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt) ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE) SLRRSSCFGGRMDRIGAQSGLGCNSFRY Carperitide ATRIAL NATRIURETIC PEPTIDE HUMAN Carperitide?Acetate (alpha-human atrial natriuretic peptide) 89213-87-6 Biochemicals and Reagents Amino Acids and Peptides BioChemical Peptides Natriuretic Peptides peptide