Rapacuronium
- CAS No.
- 156137-99-4
- Chemical Name:
- Rapacuronium
- Synonyms
- Raplon;Org 9487;Rapacuronium;[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-10,13-dimethyl-2-piperidin-1-yl-16-(1-prop-2-enylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
- CBNumber:
- CB91179647
- Molecular Formula:
- C37H61BrN2O4
- Molecular Weight:
- 677.81
- MDL Number:
- MFCD00870871
- MOL File:
- 156137-99-4.mol
Melting point | 184° |
---|---|
alpha | 20D -12.7° (c = 1.01 in CHCl3) |
storage temp. | Store at -20°C |
solubility | DMSO : ≥ 125 mg/mL (184.42 mM) |
FDA UNII | 65Q4QDG4KC |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H302-H312-H331 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501 |
Rapacuronium price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | R124050 | RapacuroniumBromide | 156137-99-4 | 5mg | $195 | 2021-12-16 | Buy |
TRC | R124050 | RapacuroniumBromide | 156137-99-4 | 50mg | $1540 | 2021-12-16 | Buy |
ChemScene | CS-6564 | Rapacuroniumbromide >98.0% | 156137-99-4 | 50mg | $1600 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 52923 | RapacuroniumBromide | 156137-99-4 | 50mg | $2400 | 2021-12-16 | Buy |
ChemScene | CS-6564 | Rapacuroniumbromide >98.0% | 156137-99-4 | 100mg | $2600 | 2021-12-16 | Buy |
Rapacuronium Chemical Properties,Uses,Production
Description
Rapacuronium bromide was introduced in the US as a parenterally administered adjunct to general anesthesia during surgical procedures. It is a new steroidal derivative belonging to the same class as vecuronium bromide. This 2,16-bispiperidinylandrostane derivative can be synthesized in 3 steps from the 3-hydroxy-androstan-17-one analog and finally quaternized with allyl bromide. Rapacuronium bromide is a nondepolarizing neuromuscular blocking drug with a rapid onset and a short duration of action. With a relatively low potency (ED90 = 1.15 mg/kg), Rapacuronium is expected to be substituted for the polarizing succinylcholine with very short duration of action.
Originator
Akzo Nobel (Netherlands)
Uses
Rapacuronium Bromide is an aminosteroidal nondepolarizing neuromuscular blocking agent and was used as a anesthesia.
brand name
Raplon
Rapacuronium Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3419 | 58 |
SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
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