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Rapacuronium

CAS No.
156137-99-4
Chemical Name:
Rapacuronium
Synonyms
Raplon;Org 9487;Rapacuronium;[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-10,13-dimethyl-2-piperidin-1-yl-16-(1-prop-2-enylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
CBNumber:
CB91179647
Molecular Formula:
C37H61BrN2O4
Molecular Weight:
677.81
MDL Number:
MFCD00870871
MOL File:
156137-99-4.mol
Last updated:2023-05-21 10:59:17

Rapacuronium Properties

Melting point 184°
alpha 20D -12.7° (c = 1.01 in CHCl3)
storage temp. Store at -20°C
solubility DMSO : ≥ 125 mg/mL (184.42 mM)
FDA UNII 65Q4QDG4KC

SAFETY

Risk and Safety Statements

Rapacuronium price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC R124050 RapacuroniumBromide 156137-99-4 5mg $195 2021-12-16 Buy
TRC R124050 RapacuroniumBromide 156137-99-4 50mg $1540 2021-12-16 Buy
ChemScene CS-6564 Rapacuroniumbromide >98.0% 156137-99-4 50mg $1600 2021-12-16 Buy
Medical Isotopes, Inc. 52923 RapacuroniumBromide 156137-99-4 50mg $2400 2021-12-16 Buy
ChemScene CS-6564 Rapacuroniumbromide >98.0% 156137-99-4 100mg $2600 2021-12-16 Buy
Product number Packaging Price Buy
R124050 5mg $195 Buy
R124050 50mg $1540 Buy
CS-6564 50mg $1600 Buy
52923 50mg $2400 Buy
CS-6564 100mg $2600 Buy

Rapacuronium Chemical Properties,Uses,Production

Description

Rapacuronium bromide was introduced in the US as a parenterally administered adjunct to general anesthesia during surgical procedures. It is a new steroidal derivative belonging to the same class as vecuronium bromide. This 2,16-bispiperidinylandrostane derivative can be synthesized in 3 steps from the 3-hydroxy-androstan-17-one analog and finally quaternized with allyl bromide. Rapacuronium bromide is a nondepolarizing neuromuscular blocking drug with a rapid onset and a short duration of action. With a relatively low potency (ED90 = 1.15 mg/kg), Rapacuronium is expected to be substituted for the polarizing succinylcholine with very short duration of action.

Originator

Akzo Nobel (Netherlands)

Uses

Rapacuronium Bromide is an aminosteroidal nondepolarizing neuromuscular blocking agent and was used as a anesthesia.

brand name

Raplon

Rapacuronium Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 19)Suppliers
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TargetMol Chemicals Inc.
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AFINE CHEMICALS LIMITED
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3419 58
SPIRO PHARMA eric_feng1954@126.com China 9254 55
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
Rapacuronium Org 9487 Raplon [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-10,13-dimethyl-2-piperidin-1-yl-16-(1-prop-2-enylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate 156137-99-4 C37H61N2O4Br C37H61BrN2O4