Sapacitabine
- CAS No.
- 151823-14-2
- Chemical Name:
- Sapacitabine
- Synonyms
- CNDAC;CS-682;CYC 682;CS-2513;Sapacitabine;10G, 50G, 100G, 1KG;Sapacitabine (CS682;Sapacitabine (CYC682);CYC 682; CYC-682; CS-682; CS682; CS 682;1-(2-Deoxy-2-cyano-β-D-arabinofuranosyl)cytosine
- CBNumber:
- CB91261450
- Molecular Formula:
- C26H42N4O5
- Molecular Weight:
- 490.64
- MDL Number:
- MFCD00919466
- MOL File:
- 151823-14-2.mol
- MSDS File:
- SDS
| Melting point | >177°C (dec.) |
|---|---|
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| pka | 10.04±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | W335P73C3L |
| NCI Drug Dictionary | sapacitabine |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Sapacitabine price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2594 | Sapacitabine | 151823-14-2 | 5mg | $78.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2594 | Sapacitabine | 151823-14-2 | 25mg | $395 | 2024-03-01 | Buy |
| TRC | S116505 | Sapacitabine | 151823-14-2 | 5mg | $120 | 2021-12-16 | Buy |
| Usbiological | 465855 | Sapacitabine | 151823-14-2 | 1mg | $360 | 2021-12-16 | Buy |
| ChemScene | CS-0006340 | Sapacitabine 98.51% | 151823-14-2 | 100mg | $1240 | 2021-12-16 | Buy |
Sapacitabine Chemical Properties,Uses,Production
Uses
Sapacitabine, it is an orally available nucleoside analog prodrug of CNDAC that acts through a dual mechanism. It has potential use in chemotherapy.
Definition
ChEBI: Sapacitabine is a nucleoside analogue resulting from the formal condensation of the carboxy group of hexadecanoic acid with the amino group of CNDAC. It is the prodrug of CNDAC and is currently in clinical development for the treatment of acute myeloid leukemia (AML). It has a role as an antimetabolite, an antineoplastic agent, a prodrug and a DNA synthesis inhibitor. It is a nucleoside analogue, a nitrile and a secondary carboxamide. It is functionally related to a hexadecanoic acid and a CNDAC.
Biochem/physiol Actions
Sapacitabine is an orally active prodrug of nucleoside analog CNDAC that exhibits potent anti-tumor activity in both blood and solid tumors. CNDAC incorporates into DNA where it causes single-strand breaks (SSBs), which are converted into double strand breaks (DSBs) during S phase.
Sapacitabine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 10027 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
View Lastest Price from Sapacitabine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Sapacitabine
151823-14-2
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
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- Sapacitabine
151823-14-2
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co