(1'S,2'S)-NICOTINE 1'-OXIDE
- CAS No.
- 51095-86-4
- Chemical Name:
- (1'S,2'S)-NICOTINE 1'-OXIDE
- Synonyms
- S,2’Nicotine Impurity 1;S)-Nicotine-1’Nicotine-cis-N-oxide;(1's2's)-Nicotine-N'-oxide;(1'S,2'S)-NICOTINE 1'-OXIDE;(1S,2S)-syn-Nicotine N'-oxide;(1'S,2'S)-TRANS-NICOTINE 1'-OXIDE;(1'S,2'S)-trans-Nicotine-1'-N-oxide;3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]
- CBNumber:
- CB9131437
- Molecular Formula:
- C10H14N2O
- Molecular Weight:
- 178.23
- MDL Number:
- MFCD00869528
- MOL File:
- Mol file
- MSDS File:
- SDS
| Melting point | 182-183°C |
|---|---|
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | A crystalline solid |
| pka | 4.63±0.40(Predicted) |
| Stability | Hygroscopic |
| FDA UNII | 6V35J35GP5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS09,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H331-H311-H411-H301 | |||||||||
| Precautionary statements | P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501 | |||||||||
| NFPA 704 |
|
(1'S,2'S)-NICOTINE 1'-OXIDE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16413 | (1'S,2'S)-Nicotine-1'-oxide ≥98% | 51095-86-4 | 25mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 16413 | (1'S,2'S)-Nicotine-1'-oxide ≥98% | 51095-86-4 | 50mg | $176 | 2024-03-01 | Buy |
| Cayman Chemical | 16413 | (1'S,2'S)-Nicotine-1'-oxide ≥98% | 51095-86-4 | 100mg | $330 | 2024-03-01 | Buy |
| TRC | N427500 | (1’S,2’S)-Nicotine1’-Oxide | 51095-86-4 | 250mg | $490 | 2021-12-16 | Buy |
| TRC | N427500 | (1’S,2’S)-Nicotine1’-Oxide | 51095-86-4 | 100mg | $180 | 2021-12-16 | Buy |
(1'S,2'S)-NICOTINE 1'-OXIDE Chemical Properties,Uses,Production
Chemical Properties
Off-White to Yellow Solid
Uses
Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
Uses
Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine
Definition
ChEBI: Trans-(S)-nicotine N(1')-oxide is an (S)-nicotine N(1')-oxide in which the N(1')-methyl group is on the opposite side of the pyrrolidine ring to the pyridine substituent. The major species at pH 7.3.
(1'S,2'S)-NICOTINE 1'-OXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(1'S,2'S)-NICOTINE 1'-OXIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5654 | 65 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |