kaurenoic acid
- CAS No.
- 6730-83-2
- Chemical Name:
- kaurenoic acid
- Synonyms
- NSC 339145;kaurenoate;Cunabic acid;kaurenoic acid;Kauren-19-oic acid;ent-kaur-16-en-19-oicaci;Kaurane-16-ene-18-oic acid;(-)-Kaur-16-en-18-oic acid;ent-Kaur-16-en-19-oic acid;Kaur-16-en-18-oic acid,(4a)-
- CBNumber:
- CB91316121
- Molecular Formula:
- C20H30O2
- Molecular Weight:
- 302.45
- MDL Number:
- MFCD28978039
- MOL File:
- 6730-83-2.mol
- MSDS File:
- SDS
| Melting point | 171-172 °C |
|---|---|
| Boiling point | 426.6±34.0 °C(Predicted) |
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 10 mg/ml |
| form | A solid |
| pka | 4.70±0.40(Predicted) |
| FDA UNII | D572D9R2TZ |
kaurenoic acid price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00177 | Kaurenoic acid ≥95% (LC/MS-ELSD) | 6730-83-2 | 1mg | $489 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL84229 | Kaurenoic acid phyproof? Reference Substance | 6730-83-2 | 10MG | $574 | 2024-03-01 | Buy |
| Cayman Chemical | 28957 | Kaurenoic Acid | 6730-83-2 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 28957 | Kaurenoic Acid | 6730-83-2 | 5mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 28957 | Kaurenoic Acid | 6730-83-2 | 10mg | $142 | 2024-03-01 | Buy |
kaurenoic acid Chemical Properties,Uses,Production
Description
Kaurenoic acid is a diterpene that has been found in C. langsdorffii and has diverse biological activities, including anticancer, antibacterial, antioxidant, and anti-inflammatory properties. It is cytotoxic to 22Rv1 and LNCaP prostate, HT-29, HCT116, SW480, and SW620 colon, and MCF-7 breast cancer cells with IC50 values ranging from 15.03 to 48.87 μg/ml. Kaurenoic acid is active against S. epidermidis, S. capitis, E. faecalis, and S. haemolyticus in vitro (MICs = 6.25-12.5 μg/ml). Kaurenoic acid (50 and 100 mg/kg) reduces colonic myeloperoxidase (MPO) activity and malondialdehyde (MDA) levels in a rat model of acetic acid-induced colitis, as well as colonic tissue damage, leukocytic infiltration, and submucosal edema when administered at a dose of 100 mg/kg.
Uses
ent-Kaurenoic Acid can be used in biological study. Kinetic profile of guaco syrup metabolites like coumarin, 7-hydroxycoumarin, o-coumaric acid, kaurenoic acid can be performed for identification of alternative route of coumarin metabolism in human plasma.
Definition
ChEBI: An ent-kaurane diterpenoid that is ent-kauran-19-oic acid in which a double bond is present at position 16(17); exhibits anticancer and anti-HIV 1 activity.
kaurenoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
View Lastest Price from kaurenoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | kaurenoic acid
6730-83-2
|
US $8.00-6.00 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-02-24 | Kaurenoic acid
6730-83-2
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2020-01-13 | kaurenoic acid
6730-83-2
|
US $1.00 / KG | 1KG | 98%HPLC | 10 tons | Career Henan Chemical Co |
-
- kaurenoic acid
6730-83-2
- US $8.00-6.00 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Kaurenoic acid
6730-83-2
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- kaurenoic acid
6730-83-2
- US $1.00 / KG
- 98%HPLC
- Career Henan Chemical Co