ChemicalBook
Chinese Japanese Germany Korea

Estradiol benzoate

Estradiol benzoate
Estradiol benzoate structure
CAS No.
50-50-0
Chemical Name:
Estradiol benzoate
Synonyms
EBZ;MEE;ODB;folone;diogynb;ESTON-B;Diogyn B;Solestro;Graafina;NSC-9566
CBNumber:
CB9131644
Molecular Formula:
C25H28O3
Formula Weight:
376.5
MOL File:
50-50-0.mol

Estradiol benzoate Properties

Melting point:
191-198 °C(lit.)
alpha 
D25 +58 to +63° (c = 2 in dioxane)
Boiling point:
465.03°C (rough estimate)
Density 
1.0493 (rough estimate)
refractive index 
1.5460 (estimate)
storage temp. 
2-8°C
solubility 
Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
form 
neat
pka
15.06±0.40(Predicted)
Water Solubility 
0.4mg/L(25 ºC)
Merck 
3703
BRN 
3107526
CAS DataBase Reference
50-50-0(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
1S4CJB5ZGN
NIST Chemistry Reference
Estradiol benzoate(50-50-0)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H351-H360
Precautionary statements  P201-P280-P308+P313-P281
Hazard Codes  T
Risk Statements  60-61-40
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  KG4050000
8
HS Code  29372319

Estradiol benzoate price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E8515 β-Estradiol 3-benzoate ≥97% 50-50-0 1g $90.7 2021-12-16 Buy
Sigma-Aldrich E1600000 Estradiol benzoate European Pharmacopoeia (EP) Reference Standard 50-50-0 $190 2021-12-16 Buy
Sigma-Aldrich BP396 Estradiol benzoate British Pharmacopoeia (BP) Reference Standard 50-50-0 $220 2021-12-16 Buy
Sigma-Aldrich 1251000 Estradiol benzoate United States Pharmacopeia (USP) Reference Standard 50-50-0 250mg $366 2021-12-16 Buy
Cayman Chemical 10006487 Estradiol Benzoate ≥98% 50-50-0 500mg $25 2021-12-16 Buy

Estradiol benzoate Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

antiacne, antineoplastic

Uses

Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.

Uses

Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.

Definition

ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.

Clinical Use

Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.

Estradiol benzoate synthesis

50-28-2
98-88-4
50-50-0
Synthesis of Estradiol benzoate from β-Estradiol and Benzoyl chloride

Estradiol benzoate Preparation Products And Raw materials

Raw materials

Preparation Products


Estradiol benzoate Suppliers

Global( 344)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Rixing Chemical CO.,LTD
13237129059
- info@rixingchemi.com CHINA 229 55
Hebei Bonster Technology Co.,Limited
+86-13315996897
0086-13315996897 Wendy@bsterltd.com CHINA 998 58
Wuhan Biocar Pharmacy Co., Ltd.
+8613669031409
+8613669031409 jason@biocar.cn China 456 58
Guangzhou Biocar Biotechnology Co.,Ltd.
+8613397196830
027-86589876 carrie@gzbiocar.cn China 402 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15418 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 497 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com China 9165 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 567 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58

View Lastest Price from Estradiol benzoate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-28 Estradiol Benzoate
50-50-0
US $1.00 / g 1000g 99% 20ton/month Wuhan Aoliqisi New Material Technology Co., Ltd.
2022-01-26 Estradiol Benzoate
50-50-0
US $9.90-99.00 / g/Bag 10g/Bag 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets,Customized packaging 100KG Wuhan Biocar Pharmacy Co., Ltd.
2022-01-25 Estradiol Benzoate
50-50-0
US $1.00 / g 10g 99.5% 1000kg Guangzhou Biocar Biotechnology Co.,Ltd.

Estradiol benzoate Spectrum


50-50-0(Estradiol benzoate)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved