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Estradiol benzoate

CAS No.
50-50-0
Chemical Name:
Estradiol benzoate
Synonyms
ODB;MEE;Oestradiol benzoate;EBZ;folone;17β-Estradiol benzoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;ESTON-B;diogynb;Graafina
CBNumber:
CB9131644
Molecular Formula:
C25H28O3
Molecular Weight:
376.5
MDL Number:
MFCD00003692
MOL File:
50-50-0.mol
MSDS File:
SDS
Last updated:2024-03-27 16:40:14

Estradiol benzoate Properties

Melting point 191-198 °C(lit.)
alpha D25 +58 to +63° (c = 2 in dioxane)
Boiling point 465.03°C (rough estimate)
Density 1.0493 (rough estimate)
refractive index 1.5460 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
pka 15.06±0.40(Predicted)
color White
Water Solubility 0.4mg/L(25 ºC)
Merck 3703
BRN 3107526
CAS DataBase Reference 50-50-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1S4CJB5ZGN
NIST Chemistry Reference Estradiol benzoate(50-50-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H351-H360FD
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  T
Risk Statements  60-61-40
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  KG4050000
8
HS Code  29372319

Estradiol benzoate price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E8515 β-Estradiol 3-benzoate ≥97% 50-50-0 1g $111 2024-03-01 Buy
Sigma-Aldrich PHR2858 Estradiol Benzoate certified reference material, pharmaceutical secondary standard 50-50-0 500MG $286 2024-03-01 Buy
Sigma-Aldrich BP396 Estradiol benzoate British Pharmacopoeia (BP) Reference Standard 50-50-0 50MG $220 2024-03-01 Buy
Sigma-Aldrich 1251000 Estradiol benzoate United States Pharmacopeia (USP) Reference Standard 50-50-0 250mg $436 2024-03-01 Buy
Cayman Chemical 10006487 Estradiol Benzoate ≥98% 50-50-0 500mg $32 2024-03-01 Buy
Product number Packaging Price Buy
E8515 1g $111 Buy
PHR2858 500MG $286 Buy
BP396 50MG $220 Buy
1251000 250mg $436 Buy
10006487 500mg $32 Buy

Estradiol benzoate Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.

Uses

antiacne, antineoplastic

Uses

Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.

Definition

ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.

Clinical Use

Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.

53-16-7
50-50-0
Synthesis of Estradiol benzoate from Estrone

Estradiol benzoate Preparation Products And Raw materials

Global( 429)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Bonster Technology Co.,Limited
+8613315996897 bsterltd.wendy@gmail.com China 796 58
Wuhan Biocar Pharmacy Co., Ltd.
+86-13669031409 +8613669031409 jason@biocar.cn China 742 58
Shenzhen Monkono Technology Co.,Ltd
+86-17063441314 sansbiotech@outlook.com China 677 58
Shanghai Chinqesen Biotechnology Co., Ltd.
+86-16628886292 +86-19521323435 sales2@qschem-pharma.com China 202 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5990 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118 xie@china-sinoway.com China 990 58
Hong Kong Excellence Biotechnology Co., Ltd.
+86-86-18838029171 +8618126314766 ada@sh-teruiop.com China 892 58
Wuhan Haorong Biotechnology Co.,ltd
+8618565342920 sales@chembj.net China 268 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Sigma Audley
+86-18336680971 +86-18126314766 nova@sh-teruiop.com China 524 58

View Lastest Price from Estradiol benzoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Estradiol Benzoate pictures 2024-03-29 Estradiol Benzoate
50-50-0
US $20.00-10.00 / kg 1kg 98% 20 Hebei Kangcang new material Technology Co., LTD
Estradiol Benzoate pictures 2024-03-29 Estradiol Benzoate
50-50-0
US $9.00-60.00 / g 10g 99% 10 tons Hebei Kangcang new material Technology Co., LTD
Estradiol benzoate pictures 2024-03-27 Estradiol benzoate
50-50-0
US $3.00-1.00 / kg 1kg 99.9% 10 tons Shanghai Aosiris new Material Technology Co., LTD
  • Estradiol Benzoate pictures
  • Estradiol Benzoate
    50-50-0
  • US $20.00-10.00 / kg
  • 98%
  • Hebei Kangcang new material Technology Co., LTD
  • Estradiol Benzoate pictures
  • Estradiol Benzoate
    50-50-0
  • US $9.00-60.00 / g
  • 99%
  • Hebei Kangcang new material Technology Co., LTD
  • Estradiol benzoate pictures
  • Estradiol benzoate
    50-50-0
  • US $3.00-1.00 / kg
  • 99.9%
  • Shanghai Aosiris new Material Technology Co., LTD
1,3,5(10)-Estratriene-3,17-diol-3-benzoate 1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate 1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate BETA-ESTRADIOL 3-BENZOATE BETA-ESTRADIOL BENZOATE B-ESTRADIOL-3-BENZOATE 17beta-Estradiol monobenzoate 17-beta-estradiolmonobenzoate 17-beta-Oestradiol 3-benzoate 17-beta-oestradiol3-benzoate 17-Hydroxyestra-1(10),2,4-trien-3-yl benzoate beta-oestradiolbenzoate De Graafina degraafina Diffollisterol 3,17b-dihydroxy-1,3,5(10)-estratriene 3-benzoate 3-Benzoyloxy-17β-hydroxyestra-1,3,5(10)-triene Agofollin Depot Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-benzoate Estradiol, 3-benzoate (8CI) Diffolistedrol ESTRADIOLBENZOATE,POWDER ESTRADIOL BENZATE 1,3,5(10)-Estratriene-3,17β-diol 3-benzoate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate, 3-Benzoyloxy-17β-estrol [(8R,9S,13S,14S,17S)-17-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] benzoate 17β-(Benzoyloxy)estra-1,3,5(10)-trien-3-ol 17β-Estradiol 17-benzoate 17BETA-ESTRADIOL 3-BENZOATE VETRANAL250 BETA-ESTRADIOL-3-BENZOATE-CARC. Estra-1,3,5(10)-triene-3,17β-diol 3-benzoate 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-benzoate 3-Benzoate 17β-estradiol3-benzoate 3-(benzoyloxy)estra-1,3,5(10)-trien-17β-ol Benovocylin Benzestrofol Benzhormovarine Benzoate d'oestradiol benzoated’oestradiol Benzoestrofol Benzoestrofol difolliculin Benzofoline Benzogynestryl Benzo-Gynoestryl Benzoic acid estradiol benzoicacidestradiol Benztrone beta-Oestradiol 3-benzoate beta-Oestradiol benzoate beta-oestradiol3-benzoate Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-benzoate estra-1,3,5(10)-triene-3,17-diol(17-beta)-3-benzoate Estradiol monobenzoate Estradiol, 3-benzoate estradiol,3-benzoate Estradiol-17beta 3-benzoate Estradiol-17beta benzoate estradiol-17-beta-3-benzoate