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6-aminocarbovir

CAS No.
124752-25-6
Chemical Name:
6-aminocarbovir
Synonyms
6-aminocarbovir;Abacavir Impurity C;Descyclopropyl Abacavir;Abacavir amine impurity;(Abacavir EP Impurity C);Abacavir Related CoMpound A;Abacavir Sulfate Impurity C;Descyclopropyl Abacavir (USP);Abacavir Sulfate EP Impurity C;Abacavir USP Related Compound A
CBNumber:
CB91326700
Molecular Formula:
C11H14N6O
Molecular Weight:
246.27
MDL Number:
MFCD00869644
MOL File:
124752-25-6.mol
Last updated:2023-04-23 13:52:06

6-aminocarbovir Properties

Melting point 180-182°C
Boiling point 628.2±65.0 °C(Predicted)
Density 1.75±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka 14.86±0.10(Predicted)
color Off-White to Pale Yellow
FDA UNII F795V26W54

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  41-43
Safety Statements  26-36/37-39
HS Code  2933599550

6-aminocarbovir price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2064 Abacavir Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 124752-25-6 50mg $803 2024-03-01 Buy
Sigma-Aldrich 1000420 Abacavir Related Compound A 124752-25-6 20mg $1360 2024-03-01 Buy
TRC D288865 DescyclopropylAbacavir 124752-25-6 5mg $145 2021-12-16 Buy
Usbiological 008302 Descyclopropyl Abacavir 124752-25-6 5mg $460 2021-12-16 Buy
Biosynth Carbosynth FD21165 Descyclopropyl abacavir 124752-25-6 2mg $578.1 2021-12-16 Buy
Product number Packaging Price Buy
PHR2064 50mg $803 Buy
1000420 20mg $1360 Buy
D288865 5mg $145 Buy
008302 5mg $460 Buy
FD21165 2mg $578.1 Buy

6-aminocarbovir Chemical Properties,Uses,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Abacavir Intermediate.

Uses

Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

6-aminocarbovir Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12382 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9823 79
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973186 4009686088 3193328036@qq.com China 18352 68
Abacavir Related CoMpound A 6-aminocarbovir (-)-2,6-Diamino-9-[(1R)-4β-(hydroxymethyl)-2-cyclopentene-1β-yl]-6,9-dihydro-1H-purine 2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S-cis)- Descyclopropyl Abacavir Abacavir Related Compound A (20 mg) ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol) (1S,4R)-4-(2,6-DiaMino-9H-purin-9-yl)-2-cyclopentene-1-Methanol (1α,4α)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentenyl-carbinol Abacavir Impurity 3(Abacavir EP Impurity C) (Abacavir EP Impurity C) [(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol Descyclopropyl Abacavir (USP) 2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S,4R)- Abacavir amine impurity [(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-en-1- yl]methanol Abacavir Related Compound A ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol) (1000420) Abacavir Sulfate - Impurity C (Freebase) Abacavir USP Related Compound A Abacavir Sulfate Impurity C Abacavir Impurity C Abacavir Sulfate EP Impurity C 124752-25-6 Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals