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kerasin

CAS No.
536-13-0
Chemical Name:
kerasin
Synonyms
Cerasine;Galactosylceramides (non-hydroxy);Galactosylcerebrosides (non-hydroxy);Galactosylceramide (non-hydroxy) (bovine);N-[(1R,2S,E)-1-[(β-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]tetracosanamide
CBNumber:
CB91396327
Molecular Formula:
C48H91NO8
Molecular Weight:
810.23804
MDL Number:
MOL File:
536-13-0.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17

kerasin Properties

storage temp. Store at -20°C
solubility CHCl3:CH3OH:H2O (3:2:1): Soluble
form A solid

kerasin price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24835 Galactosylcerebrosides (non-hydroxy) ≥98% 536-13-0 1mg $43 2024-03-01 Buy
Cayman Chemical 24835 Galactosylceramides (non-hydroxy) ≥98% 536-13-0 10mg $209 2024-03-01 Buy
Cayman Chemical 24835 Galactosylcerebrosides (non-hydroxy) ≥98% 536-13-0 500μg $25 2021-12-16 Buy
Cayman Chemical 24835 Galactosylcerebrosides (non-hydroxy) ≥98% 536-13-0 5mg $116 2024-03-01 Buy
Product number Packaging Price Buy
24835 1mg $43 Buy
24835 10mg $209 Buy
24835 500μg $25 Buy
24835 5mg $116 Buy

kerasin Chemical Properties,Uses,Production

Description

Galactosylceramides are glycosphingolipids that contain galactose attached to a ceramide containing an N-acyl hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatide , found primarily in nerve tissues, and are the main glycosphingolipids in the central nervous system.1,2 Galactosylceramides are involved in a multitude of cellular processes including cell agglutination, cellular signaling in glycosynapses, cellular development, and activation of T cells.1,2,3 They accumulate in globoid cells in the brain of patients with Krabbe disease, a disorder characterized by a deficiency in galactosylcerebrosidase activity.2 This product contains non-hydroxy galactosylceramides with primarily C24:0 and C24:1 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone.

Definition

ChEBI: Beta-D-galactosyl-N-(tetracosanoyl)sphingosine is a N-acyl-beta-D-galactosylsphingosine in which the acyl group is tetracosananoyl. It has a role as a mouse metabolite. It is functionally related to a tetracosanoic acid.

References

1. Boggs, J.M., Gao, W., Zhao, J., et al. Participation of galactosylceramide and sulfatide in glycosynapses between oligodendrocyte or myelin membranes FEBS Lett. 584(9),1771-1778(2010).
2. Wenger, D.A., Rafi, M.A., and Luzi, P. Krabbe disease: One hundred years from the bedside to the bench to the bedside J. Neurosci. Res. 94(11),982-989(2016).
3. Birkholz, A.M., Howell, A.R., and Kronenberg, M. The α and Ω of galactosylceramides in T cell immune function J. Biol. Chem. 290(25),15365-15370(2015).

kerasin Preparation Products And Raw materials

Raw materials

Preparation Products

kerasin Suppliers

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Cerasine N-[(1R,2S,E)-1-[(β-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]tetracosanamide Galactosylcerebrosides (non-hydroxy) Galactosylceramides (non-hydroxy) Galactosylceramide (non-hydroxy) (bovine) 536-13-0