QUERCETINPENTAACETATE
- CAS No.
- 1064-06-8
- Chemical Name:
- QUERCETINPENTAACETATE
- Synonyms
- Quercetin acetate;Pentaacetylquercetin;Quercetine pentaacetate;3,3',4',5,7-Pentaacetoxyflavone;3,3',4',5,7-Penta(acetyloxy)flavone;3,5,7-triacetoxy-2-(3,4-diacetoxy-phenyl)-chromen-4-one;2-(3,4-diacetoxyphenyl)-4-oxo-4H-chromene-3,5,7-triyl triacetate;[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate;Quercetin pentaacetate,Respiratory syncytial virus,inhibit,Inhibitor,RSV;4H-1-Benzopyran-4-one, 3,5,7-tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-
- CBNumber:
- CB91405559
- Molecular Formula:
- C25H20O12
- Molecular Weight:
- 512.42
- MDL Number:
- MFCD00219362
- MOL File:
- 1064-06-8.mol
Melting point | 193 °C |
---|---|
Boiling point | 666.4±55.0 °C(Predicted) |
Density | 1.45±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Dichloromethane, Ethyl Acetate |
form | Solid |
color | Beige |
FDA UNII | G0B9KJ0VKI |
QUERCETINPENTAACETATE price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 26694 | Pentaacetylquercetin | 1064-06-8 | 10mg | $48 | 2024-03-01 | Buy |
Cayman Chemical | 26694 | Pentaacetylquercetin | 1064-06-8 | 500mg | $1153 | 2024-03-01 | Buy |
Cayman Chemical | 26694 | Pentaacetylquercetin | 1064-06-8 | 50mg | $152 | 2024-03-01 | Buy |
Cayman Chemical | 26694 | Pentaacetylquercetin | 1064-06-8 | 100mg | $255 | 2024-03-01 | Buy |
TRC | D454465 | [5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl]Acetate | 1064-06-8 | 100mg | $250 | 2021-12-16 | Buy |
QUERCETINPENTAACETATE Chemical Properties,Uses,Production
Description
Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).
Uses
[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
QUERCETINPENTAACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
QUERCETINPENTAACETATE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
Beijing Stronger Science Co., Ltd. | 0531-88924771 15614660963 | elsa.hang@strongerscience.com | China | 10624 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
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