α-(p-Aminophenyl)butyric acid
- CAS No.
- 29644-97-1
- Chemical Name:
- α-(p-Aminophenyl)butyric acid
- Synonyms
- YD201;NSC 27530;Aids019033;Aids-019033;Indobufen Impurity 7;Indobufen Impurity D;Indobufen Impurity 16;Indobufen impurities842;Indoibufen intermediate 1;α -(p-aMinophenyl)butyriacid
- CBNumber:
- CB91451400
- Molecular Formula:
- C10H13NO2
- Molecular Weight:
- 179.22
- MDL Number:
- MFCD00598059
- MOL File:
- 29644-97-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(4-Aminophenyl)butanoicacid | A615540 | 500mg | $675 |
| 2-(4-Aminophenyl)butanoicacid | 3036AB | 1g | $500 |
| 2-(4-AMINO-PHENYL)-BUTYRIC ACID 95.00% | CHM0984997 | 5MG | $502.38 |
| 2-(4-Amino-phenyl)-butyricacid 95%+ | SB-14K-002 | 5g | $862.75 |
| 2-(4-Aminophenyl)butanoicacid 95% | A155756 | 100mg | $29 |
| More product size | |||
| Melting point | 142-143℃ |
|---|---|
| Boiling point | 354.6±17.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3 (20 ºC 760 Torr) |
| vapor pressure | 13-18hPa at 20-25℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 4.01±0.10(Predicted) |
| form | Solid:particulate/powder |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C10H13NO2/c1-2-9(10(12)13)7-3-5-8(11)6-4-7/h3-6,9H,2,11H2,1H3,(H,12,13) |
| InChIKey | WAPLXGPARWRGJO-UHFFFAOYSA-N |
| SMILES | C1(C=CC(N)=CC=1)C(CC)C(=O)O |
| LogP | -1.3 at 19.8℃ and pH7 |
| Surface tension | 75.21mN/m at 1g/L and 20℃ |
| EWG's Food Scores | 1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Toxicity | mouse,LD50,intraperitoneal,1180mg/kg (1180mg/kg),Farmaco, Edizione Scientifica. Vol. 13, Pg. 286, 1958. |
α-(p-Aminophenyl)butyric acid price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A615540 | 2-(4-Aminophenyl)butanoicacid | 29644-97-1 | 500mg | $675 | 2021-12-16 | Buy |
| AK Scientific | 3036AB | 2-(4-Aminophenyl)butanoicacid | 29644-97-1 | 1g | $500 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0984997 | 2-(4-AMINO-PHENYL)-BUTYRIC ACID 95.00% | 29644-97-1 | 5MG | $502.38 | 2021-12-16 | Buy |
| Acints | SB-14K-002 | 2-(4-Amino-phenyl)-butyricacid 95%+ | 29644-97-1 | 5g | $862.75 | 2021-12-16 | Buy |
| Ambeed | A155756 | 2-(4-Aminophenyl)butanoicacid 95% | 29644-97-1 | 100mg | $29 | 2021-12-16 | Buy |
α-(p-Aminophenyl)butyric acid Chemical Properties,Uses,Production
Pharmaceutical Applications
α-(p-Aminophenyl)butyric acid can be used as a ligand for the development of GABA receptor modulators, which are crucial in the treatment of neurological disorders. Its structural similarity to GABA allows it to interact with GABA receptors, potentially modulating their activity and offering therapeutic benefits.
Synthesis
7463-53-8
29644-97-1
2-(4-Nitrophenyl)butyric acid (10.0 g, 47.8 mmol) and carbon-loaded palladium catalyst (0.25 g) were suspended in methanol (100 mL). The reaction mixture was stirred overnight at room temperature and 1 atm hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the diatomaceous earth was washed with methanol (50 mL). The filtrates were combined and concentrated using a rotary evaporator. Water (200 mL) was added to the concentrate and recrystallized. The mixture was cooled in an ice bath to precipitate a pink solid product. The solid was collected by vacuum filtration and dried under vacuum to give 5.8 g of 2-(4-aminophenyl)butyric acid in 68% yield. The product was characterized by the following data: NMR (400 MHz, DMSO-d6) δ 11.88 (s, 1H, COOH), 6.73 (d, J = 8.4 Hz, 2H, ArH), 6.31 (d, J = 8.4 Hz, 2H, ArH), 4.77 (s, 2H, NH2), 2.98 (t, J = 7.5 Hz, 1H, CH). 1.68 (m, 1H, CH2), 1.39 (m, 1H, CH2), 0.62 (t, J = 7.3 Hz, 3H, CH3); MS (ESI) m/z 202.1 ([M+Na]+).
References
[1] Patent: WO2017/205451, 2017, A1. Location in patent: Paragraph 0293
[2] Bulletin de la Societe Chimique de France, 1927, vol. <4> 41, p. 451
[3] Patent: US5214191, 1993, A
[4] Patent: CN106631974, 2017, A. Location in patent: Paragraph 0028; 0029; 0031; 0032; 0033
α-(p-Aminophenyl)butyric acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing CosmicKoda Chemical Technology Co.,Ltd | +86-15311061293 +86-15311061293 | JeanWangCosmicKoda@outlook.com | China | 49 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-17392712697 | 1022@dideu.com | China | 3995 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from α-(p-Aminophenyl)butyric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | Benzeneacetic acid,4-amino-a-ethyl-
29644-97-1
|
US $0.00-0.00 / KG | 1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-10-13 | Benzeneacetic acid,4-amino-a-ethyl-
29644-97-1
|
US $22.00-88.00 / kg | 1kg | 99% | 50kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-09-26 | α-(p-Aminophenyl)butyric acid
29644-97-1
|
US $100.00-92.00 / kilograms | 1kilograms | 99% | 100tons | Hebei Dangtong Import and export Co LTD |
-
- Benzeneacetic acid,4-amino-a-ethyl-
29644-97-1
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Benzeneacetic acid,4-amino-a-ethyl-
29644-97-1
- US $22.00-88.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- α-(p-Aminophenyl)butyric acid
29644-97-1
- US $100.00-92.00 / kilograms
- 99%
- Hebei Dangtong Import and export Co LTD
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