methyl quinoline-3-carboxylate
- CAS No.
- 53951-84-1
- Chemical Name:
- methyl quinoline-3-carboxylate
- Synonyms
- Methyl 3-quinolinecarboxylate;methyl quinoline-3-carboxylate;Methyl-Quinolone-3-Carboxylate;Quinoline-3-carboxylic acid methyl ester;3-Quinolinecarboxylic acid, methyl ester
- CBNumber:
- CB91454274
- Molecular Formula:
- C11H9NO2
- Molecular Weight:
- 187.19
- MDL Number:
- MFCD03550859
- MOL File:
- 53951-84-1.mol
- MSDS File:
- SDS
methyl quinoline-3-carboxylate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M327223 | MethylQuinoline-3-carboxylate | 53951-84-1 | 500mg | $155 | 2021-12-16 | Buy |
| Matrix Scientific | 083546 | Methyl quinoline-3-carboxylate 95% | 53951-84-1 | 1g | $414 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0303200 | METHYL QUINOLINE-3-CARBOXYLATE 95.00% | 53951-84-1 | 5MG | $502.06 | 2021-12-16 | Buy |
| AK Scientific | Z4848 | Methylquinoline-3-carboxylate | 53951-84-1 | 10g | $691 | 2021-12-16 | Buy |
| AK Scientific | Z4848 | Methylquinoline-3-carboxylate | 53951-84-1 | 25g | $1211 | 2021-12-16 | Buy |
methyl quinoline-3-carboxylate Chemical Properties,Uses,Production
Synthesis Reference(s)
Journal of Medicinal Chemistry, 25, p. 1081, 1982 DOI: 10.1021/jm00351a015
Synthesis
67-56-1
6480-68-8
53951-84-1
General procedure for the synthesis of methyl 3-quinolinecarboxylate from methanol and quinoline-3-carboxylic acid: quinoline-3-carboxylic acid (3 g, 17.32 mmol) was dissolved in methanol (30 mL) and cooled at 0°C in an ice bath. Subsequently, thionyl chloride (1.264 mL, 17.32 mmol) was added slowly and dropwise, then the reaction mixture was heated to 80°C and kept overnight. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the methanol was evaporated under reduced pressure and the resulting residue was alkalized with saturated sodium bicarbonate solution to pH 7 to 8, precipitating a white solid. After filtration and drying, methyl 3-quinolinecarboxylate (3.2 g, 99% yield) was obtained as a white solid; mass spectrometry (M/Z) showed a molecular ion peak of 187.3.
References
[1] Patent: WO2014/33604, 2014, A1. Location in patent: Page/Page column 48
[2] Organic and Biomolecular Chemistry, 2016, vol. 14, # 24, p. 5505 - 5510
[3] Tetrahedron Asymmetry, 2013, vol. 24, # 18, p. 1142 - 1147
[4] Patent: US2016/122303, 2016, A1. Location in patent: Paragraph 0078
[5] Tetrahedron Asymmetry, 2010, vol. 21, # 18, p. 2307 - 2313
methyl quinoline-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49983 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 13681763483 | product02@bidepharm.com | China | 42446 | 60 |
View Lastest Price from methyl quinoline-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | Methyl quinoline-3-carboxylate
53951-84-1
|
US $1.00 / KG | 1KG | 98% HPLC | 10 tons/month | Career Henan Chemical Co |
-
- Methyl quinoline-3-carboxylate
53951-84-1
- US $1.00 / KG
- 98% HPLC
- Career Henan Chemical Co
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