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Balsalazide

Balsalazide
Balsalazide structure
CAS No.
80573-04-2
Chemical Name:
Balsalazide
Synonyms
balsalazido;BALSALAZIDE;Balsalazide D4;BALSALAZIDE SODIUM;BALSALZIDE DISODIUM;BALSALAZIDE DISODIUM SALT;5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-benzoicaci(e;(E)-5-[[4-[[(2-Carboxyethyl)amino]-carbonyl]phenyl]azo-2-hydroxybenzoic acid;Benzoic acid, 5-((1E)-(4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-;Benzoic acid, 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, (E)-
CBNumber:
CB9148828
Molecular Formula:
C17H15N3O6
Formula Weight:
357.32
MOL File:
80573-04-2.mol

Balsalazide Properties

Melting point:
254-255?C
storage temp. 
-20°C Freezer

Balsalazide price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18680 Balsalazide ≥98% 80573-04-2 5mg $45 2018-11-13 Buy
Cayman Chemical 18680 Balsalazide ≥98% 80573-04-2 10mg $86 2018-11-13 Buy
Cayman Chemical 18680 Balsalazide ≥98% 80573-04-2 25mg $191 2018-11-13 Buy
Cayman Chemical 18680 Balsalazide ≥98% 80573-04-2 50mg $360 2018-11-13 Buy

Balsalazide Chemical Properties,Uses,Production

Description

Colazide was launched in the UK for mild to moderate acute attacks of ulcerative colitis. It can be prepared by diazotization of 3-(4-aminobenzoylamino) propionic acid followed by condensation with salicylic acid. Colazide, an analogue of sulfasalazine, was found to be non-toxic and non-mutagenic in the Ames test. Once ingested the molecule releases a non-toxic fragment, 4-aminobenzoyl-β-alanine (poorly absorbed - 75% excretion in stool), and the active component 5- aminosalicylic acid (Mesalazine). The exact mechanism of action is not clearly understood but it is cytoprotective and has antiinflammatory properties. Other biological effects have been observed and include the following: (a) granulocyte activation is blocked, (b) there is a reduction in myeloperoxidase activity, and (c) a reduction in the release of arachidonic acid with a concomitant decrease in prostaglandin and leucotriene (as indicated by the lack of production of LTB4) production. It can behave as a reactive oxygen species (ROS) scavenger, inhibit PAF formation, reduce IL-1 production, and antagonize TNF and NK cells. While comparable in efficacy to sulfasalazine, Colazide removes the possibility of sulfasalazine side-effects, such as, agranulocytosis, hepatotoxicity and male infertility.

Chemical Properties

Yellow Solid

Originator

Biorex (UK)

Uses

An analogue of Sulfasalazine, A prodrug of 5-Aminosalicylic Acid

Uses

An analogue of Sulfasalazine (S699084). A prodrug of 5-aminosalicylic acid where carrier molecule is 4-aminobenzoyl-β-alanine. Anti-inflammatory (gastrointestinal).

Definition

ChEBI: A monohydroxybenzoic acid consisting of 5-aminosalicylic acid (mesalazine) linked to 4-aminobenzoyl-beta-alanine via an azo bond.

brand name

Colazal (Salix).

Balsalazide Preparation Products And Raw materials

Raw materials

Preparation Products


Balsalazide Suppliers

Global( 105)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29979 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8922 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 0 58
Chongqing Chemdad Co., Ltd +86-13650506873
sales@chemdad.com CHINA 30864 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
TAIYUAN RHF CO.,LTD. +86 351 7031519
+86 351 7031519 sales@RHFChem.com China 2349 56
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1940 70

View Lastest Price from Balsalazide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Balsalazide
80573-04-2
US $1.00 / KG 1G 98% 100KG career henan chemical co

80573-04-2(Balsalazide)Related Search:


  • BALSALZIDE DISODIUM
  • BALSALAZIDE SODIUM
  • BALSALAZIDE
  • balsalazido
  • (E)-5-[[4-[[(2-Carboxyethyl)amino]-carbonyl]phenyl]azo-2-hydroxybenzoic acid
  • BALSALAZIDE DISODIUM SALT
  • Benzoic acid, 5-((1E)-(4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-
  • Benzoic acid, 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, (E)-
  • 5-[(1E)-2-[4-[[(2-Carboxyethyl)aMino]carbonyl]phenyl]diazenyl]-2-hydroxybenzoic Acid
  • Balsalazide D4
  • 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-benzoicaci(e
  • 80573-04-2
  • 80573-04-02
  • C17H15N3O6
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