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tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate structure

CAS No.: 107017-73-2

Chemical Name:: tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate

Synonyms: tert-Butyl [1-(Hydroxymethyl)cyclopropyl]carbamate;tert-butyl N-[1-(hydroxymethyl)cyclopropyl]carbamate;SKL325;Boc-ACPC-ol;Boc-1-Aminocyclopropylmethanol;N-Boc-1-AMinocyclopropylMethanol;1-(Boc-amino)cyclopropylmethanol;Boc-1-aminocyclopropane methanol;1-Boc-Amino-cyclopropanemethanol;N-BOC-1-AMINO-CYCLOPROPANEMETHANOL

CBNumber:: CB91508201

Molecular Formula:: C9H17NO3

Molecular Weight:: 187.24

MDL Number:: MFCD09749954

MOL File:: 107017-73-2.mol

MSDS File:: SDS

Last updated:2023-10-18 15:21:32

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tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Properties

Melting point	81.0 to 85.0 °C
Boiling point	294.5±9.0 °C(Predicted)
Density	1.11±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	12.24±0.20(Predicted)
color	White to Orange to Green

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P280-P305+P351+P338-P310
HS Code	2924297099

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4251	[1-(tert-Butoxycarbonylamino)cyclopropyl]methanol >97.0%(GC)	107017-73-2	200mg	$41	2024-03-01	Buy
TCI Chemical	B4251	[1-(tert-Butoxycarbonylamino)cyclopropyl]methanol >97.0%(GC)	107017-73-2	1g	$132	2024-03-01	Buy
TRC	B809783	tert-ButylN-[1-(Hydroxymethyl)cyclopropyl]carbamate	107017-73-2	250mg	$90	2021-12-16	Buy
Apolloscientific	OR350017	Boc-1-Aminocyclopropylmethanol 98%	107017-73-2	1g	$37	2021-12-16	Buy
ChemScene	CS-D0180	tert-butyl(1-(hydroxymethyl)cyclopropyl)carbamate >98.0%	107017-73-2	5g	$78	2021-12-16	Buy

Product number	Packaging	Price	Buy
B4251	200mg	$41	Buy
B4251	1g	$132	Buy
B809783	250mg	$90	Buy
OR350017	1g	$37	Buy
CS-D0180	5g	$78	Buy

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Chemical Properties,Uses,Production

Physical Form

Solid

Uses

Tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate could be converted into spirocyclopropanated analogues 14-CP and 14-CT of the insecticide Thiacloprid [1]. It can also be transformed into spirocyclopropanated analogs of Imidacloprid. This compound could be used to synthesize spirocyclopropanated five-membered ring analog 4-(3,5-Dichlorophenyl)-N-isopropyl-5-oxo-4,6-diazaspiro- [2.4]heptane-6-carboxamide[2]. tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate

Preparation

Tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate can be synthesized in three steps (40 % overall yield) from N, Ndibenzyl-2-benzyloxyacetamide starting with its reductive cyclopropanation (the de Meijere variant of the so-called Kulinkovich reaction). It can also be prepared in 56 % overall yield by monohydrolysis of commercially available diethyl cyclopropane-1,1-dicarboxylate followed by Curtius degradation of the carboxylic acid residue and subsequent reduction of the ester moiety[1].

References

[1] Brackmann F, et al. Synthesis of Spirocyclopropanated Analogues of Imidacloprid and Thiacloprid. European Journal of Organic Chemistry, 2005; 2005: 600-609.
[2] Brackmann F, et al. Synthesis of Spirocyclopropanated Analogues of Iprodione. European Journal of Organic Chemistry, 2005; 2005: 2250-2258.

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate synthesis

Synthesis of tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate from Di-tert-butyl dicarbonate and 1-Amino-1-(hydroxymethyl)cyclopropane hydrochloride

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

1-Amino-1-(hydroxymethyl)cyclopropane hydrochloride 1-(Boc-amino)cyclopropanecarboxylic acid tert-Butyl 1-(bromomethyl)cyclopropyl carbamate TERT-BUTYL (1-FORMYLCYCLOPROPYL)CARBAMATE

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Suppliers

Global( 195)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Chengdu Feibo Pharm Technology Co., Ltd	15982321820	abby@arkpharm.com	CHINA	3279	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58

Supplier	Advantage
Shanghai Boc Chemical Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Accela ChemBio Inc.	58
Chengdu Feibo Pharm Technology Co., Ltd	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58

View Lastest Price from tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-10-01	Boc-1-Aminocyclopropylmethanol 107017-73-2	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2022-05-25	N-BOC-1-AMINO-CYCLOPROPANEMETHANOL 107017-73-2	US $1.10 / g	1g	99.0% Min	100 Tons	Dideu Industries Group Limited
2019-09-05	N-BOC-1-AMINO-CYCLOPROPANEMETHANOL 107017-73-2	US $5.50 / KG	2KG	96%-99%	100kg	Career Henan Chemical Co

Boc-1-Aminocyclopropylmethanol
107017-73-2
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
107017-73-2
US $1.10 / g
99.0% Min
Dideu Industries Group Limited

N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
107017-73-2
US $5.50 / KG
96%-99%
Career Henan Chemical Co

tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Spectrum

N-BOC-1-AMINO-CYCLOPROPANEMETHANOL(107017-73-2)¹HNMR

107017-73-2(tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate)Related Search:

1-N-Boc-Aminocyclopentanecarboxylic acid 1-(Boc-amino)cyclopropanecarboxylic acid Cyclopropyl carbinol 1-AMINO-CYCLOPROPANEMETHANOL (1R,2S)-1-BOC-AMINO-2-VINYLCYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

1-BOC-3-AMINOPIPERIDINE (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID Cyclopropanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-ethenyl-, (1R,2S)-rel- tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate 1-BOC-AMINO-2-VINYLCYCLOPROPANECARBOXYLIC ACID ETHYL ESTER

(1R,2S)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID VINYL ACCA BOC-1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID (1S,2S)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID (1S,5R)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-1-CARBOXYLIC ACID

1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-ethenyl-,(1S,2R)- (1S,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID (R)-BOC-1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID

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N-BOC-1-AMINO-CYCLOPROPANEMETHANOL Boc-1-Aminocyclopropylmethanol 1-(Boc-amino)cyclopropylmethanol [1-(Hydroxymethyl)cyclopropyl]carbamicacid tert-butyl ester Carbamicacid, [1-(hydroxymethyl)cyclopropyl]-, 1,1-dimethylethyl ester (9CI) Boc-ACPC-ol tert-butyl 2-(1-aMinocyclopropyl)-2-hydroxyacetate (1-HydroxyMethyl-cyclopropyl)-carbaMic acid tert-b 2-Methyl-2-propanyl [1-(hydroxyMethyl)cyclopropyl]carbaMate [1-(tert-ButoxycarbonylaMino)cyclopropyl]Methanol N-Boc-1-AMinocyclopropylMethanol 1-(Boc-amino)cyclopropylmethanol N-Boc-1-amino-cyclopropanemethanol [1-(tert-Butoxycarbonylamino)cyclopropyl]methanol Boc-1-aminocyclopropane methanol TERT-BUTYL 1-(HYDROXYMETHYL)CYCLOPROPYLCARBAMATE(WX640242) [1-(tert-Butoxycarbonylamino)cyclopropyl]methanol > Carbamic acid, N-[1-(hydroxymethyl)cyclopropyl]-, 1,1-dimethylethyl ester N-BOC-1-AMINO-CYCLOPROPANEMETHANOL ISO 9001：2015 REACH SKL325 tert-Butyl [1-(Hydroxymethyl)cyclopropyl]carbamate tert-butyl N-[1-(hydroxymethyl)cyclopropyl]carbamate 1-Boc-Amino-cyclopropanemethanol 107017-73-2