5-Hydroxyindole
- CAS No.
- 1953-54-4
- Chemical Name:
- 5-Hydroxyindole
- Synonyms
- 1H-INDOL-5-OL;5-INDOLOL;5-Hydroxyindoline;NSC 87503;INDOL-5-OL;5-hdroxyindole;5-HYDROXYINDOLE;hydroxy-5indole;Hydroxy-5 indole;Hydroxyindole,98%
- CBNumber:
- CB9151600
- Molecular Formula:
- C8H7NO
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD00005677
- MOL File:
- 1953-54-4.mol
- MSDS File:
- SDS
| Melting point | 106-108 °C(lit.) |
|---|---|
| Boiling point | 245.66°C (rough estimate) |
| Density | 1.1475 (rough estimate) |
| refractive index | 1.5260 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | 38g/l |
| form | Crystalline Needles or Powder |
| pka | 9.98±0.40(Predicted) |
| color | beige |
| Sensitive | Light Sensitive |
| BRN | 112349 |
| InChI | InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H |
| InChIKey | LMIQERWZRIFWNZ-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(O)C=C2)C=C1 |
| CAS DataBase Reference | 1953-54-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 320UN7XZYN |
| NIST Chemistry Reference | Indol-5-ol(1953-54-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NM2430000 | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
5-Hydroxyindole price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H31859 | 5-Hydroxyindole 97% | 1953-54-4 | 1g | $70.6 | 2025-07-31 | Buy |
| TCI Chemical | H0252 | 5-Hydroxyindole >98.0%(GC) | 1953-54-4 | 100mg | $18 | 2025-07-31 | Buy |
| TCI Chemical | H0252 | 5-Hydroxyindole >98.0%(GC) | 1953-54-4 | 1g | $57 | 2025-07-31 | Buy |
| TCI Chemical | H0252 | 5-Hydroxyindole >98.0%(GC) | 1953-54-4 | 5g | $171 | 2025-07-31 | Buy |
| TRC | H943510 | 5-Hydroxyindole | 1953-54-4 | 1g | $55 | 2021-12-16 | Buy |
5-Hydroxyindole Chemical Properties,Uses,Production
Chemical Properties
beige to brown crystalline needles or powder
Uses
• ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6
Uses
5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.
Definition
ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite.
Synthesis Reference(s)
Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017
5-Hydroxyindole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12648 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20202 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12908 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 |
View Lastest Price from 5-Hydroxyindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-07 | 5-Hydroxyindole
1953-54-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-27 | 5-Hydroxyindole
1953-54-4
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-05-26 | 5-Hydroxyindole
1953-54-4
|
US $9.00 / KG | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 5-Hydroxyindole
1953-54-4
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 5-Hydroxyindole
1953-54-4
- US $30.00-10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 5-Hydroxyindole
1953-54-4
- US $9.00 / KG
- 99.9
- Hebei Chuanghai Biotechnology Co,.LTD
