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Benzyl benzoate

Description References
Benzyl benzoate
Benzyl benzoate
CAS No.
120-51-4
Chemical Name:
Benzyl benzoate
Synonyms
Zylate;ASCABIN;Scabide;Benylate;ASCABIOL;Colebenz;Scabagen;Scabanca;Scabitox;Scobenol
CBNumber:
CB9152283
Molecular Formula:
C14H12O2
Formula Weight:
212.24
MOL File:
120-51-4.mol

Benzyl benzoate Properties

Melting point:
18 °C
Boiling point:
323-324 °C(lit.)
Density 
1.118 g/mL at 20 °C(lit.)
vapor pressure 
1 mm Hg ( 125 °C)
refractive index 
n20/D 1.568(lit.)
FEMA 
2138 | BENZYL BENZOATE
FEMA 
2797 | OCTANAL
Flash point:
298 °F
storage temp. 
2-8°C
solubility 
Miscible with ethanol, alcohol, chloroform, ether, oils.
form 
Liquid
color 
Clear colorless
Water Solubility 
practically insoluble
Merck 
14,1127
BRN 
2049280
Stability:
Stable. Substances to be avoided include strong oxidizing agents. Combustible.
InChIKey
SESFRYSPDFLNCH-UHFFFAOYSA-N
CAS DataBase Reference
120-51-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzyl Benzoate(120-51-4)
EPA Substance Registry System
Benzoic acid, phenylmethyl ester(120-51-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,N
Risk Statements  22-51/53
Safety Statements  25-61-46
RIDADR  UN 3082 9 / PGIII
WGK Germany  2
RTECS  DG4200000
Autoignition Temperature 896 °F
TSCA  Yes
HazardClass  9
HS Code  29163100
Hazardous Substances Data 120-51-4(Hazardous Substances Data)
Toxicity LD50 in rats, mice, rabbits, guinea pigs (g/kg): 1.7, 1.4, 1.8, 1.0 orally (Draize)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Benzyl benzoate price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1062008 Benzyl benzoate Pharmaceutical Secondary Standard; Certified Reference Material 120-51-4 5g $62.3 2018-11-13 Buy
Sigma-Aldrich 12392 Benzyl benzoate tested according to Ph.Eur. 120-51-4 1l-f $96.8 2018-11-13 Buy
TCI Chemical B0064 Benzyl Benzoate >99.0%(GC) 120-51-4 25g $17 2018-11-22 Buy
TCI Chemical B0064 Benzyl Benzoate >99.0%(GC) 120-51-4 500g $40 2018-11-22 Buy
Alfa Aesar L03258 Benzyl benzoate, 99+% 120-51-4 250g $21.9 2018-11-13 Buy

Benzyl benzoate Chemical Properties,Uses,Production

Description

Benzyl benzoate (BnBzO) is a mediation and insect repellent. It is one of the older preparation used to treat scabies which is a skin infections caused by the mite scarcoptes scabiei since it is lethal to the mite. It is capable of killing the mite in 5 minutes. It can also be used for the treatment of lice infestation of the head and the body. Its mechanism of action is through exerting toxic effect on the nervous system of the insects, further causing its death. It is also toxic to mite ova through an unknown mechanism. It can also be used as a repellent for chiggers, ticks, and mosquitoes as well as a dye carrier, solvent of cellulose derivatives, plasticizer, and a fixative.

References

https://www.drugbank.ca/drugs/DB00676
https://en.wikipedia.org/wiki/Benzyl_benzoate

Chemical Properties

Colourless oily liquid with pleasant aromatic odour

Chemical Properties

Benzyl benzoate is a clear, colorless, oily liquid with a slightly aromatic odor. It produces a sharp, burning sensation on the tongue. At temperatures below 178℃ it exists as clear, colorless crystals.

Uses

benzyl benzoate is an anti-microbial. It can also act as a solvent, helping dissolve other substances in the product, and as a perfuming ingredient. It is the ester of benzyl alcohol and benzoic acid.

Uses

antiarteriosclerotic, hypolipaemic, hepatoprotectant

Uses

Benzyl Benzoate has seen use as an insecticide, as well as a solvent for various chemical reactions.

Uses

Used to kill lice and the mites responsible for the skin condition scabies.

Uses

As solvent of cellulose acetate, nitrocellulose and artificial musk; substitute for camphor in celluloid and plastic pyroxylin Compounds; perfume fixative; in confectionery and chewing gum flavors.

Production Methods

Benzyl benzoate is a constituent of Peru balsam and occurs naturally in certain plant species. Commercially, benzyl benzoate is produced synthetically by the dry esterification of sodium benzoate and benzoyl chloride in the presence of triethylamine or by the reaction of sodium benzylate with benzaldehyde.

brand name

Pharmaceutic necessity for Dimercaprol [Injection]. Benylate (Sterling Winthrop).

Hazard

Irritant to eyes, skin.

Pharmaceutical Applications

Benzyl benzoate is used as a solubilizing agent and nonaqueous solvent in intramuscular injections at concentrations of 0.01–46.0% v/v, and as a solvent and plasticizer for cellulose and nitrocellulose. It is also used in the preparation of spray-dried powders using nanocapsules.
However, the most widespread pharmaceutical use of benzyl benzoate is as a topical therapeutic agent in the treatment of scabies. Benzyl benzoate is also used therapeutically as a parasiticide in veterinary medicine.
Other applications of benzyl benzoate include its use as a pediculicide, and as a solvent and fixative for flavors and perfumes in cosmetics and food products.

Contact allergens

Benzyl benzoate is the ester of benzyl alcohol and benzoic acid. It is contained in Myroxylon pereirae and Tolu balsam. It is used in acaricide preparations against Sarcoptes scabiei or as a pediculicide. Direct contact may cause skin irritation, but rarely allergic contact dermatitis. As a fragrance allergen, benzyl benzoate has to be mentioned by name in EU cosmetics.

Safety

Benzyl benzoate is metabolized by rapid hydrolysis to benzoic acid and benzyl alcohol. Benzyl alcohol is then further metabolized to hippuric acid, which is excreted in the urine.
Benzyl benzoate is widely used as a 25% v/v topical application in the treatment of scabies and as an excipient in intramuscular injections and oral products. Adverse reactions to benzyl benzoate include skin irritation and hypersensitivity reactions. Oral ingestion may cause harmful stimulation of the CNS and convulsions. Benzyl benzoate should be avoided by perople with perfume allergy.
LD50 (cat, oral): 2.24 g/kg
LD50 (dog, oral): 22.44 g/kg
LD50 (guinea pig, oral): 1.0 g/kg
LD50 (mouse, oral): 1.4 g/kg
LD50 (rabbit, oral): 1.68 g/kg
LD50 (rabbit, skin): 4.0 g/kg
LD50 (rat, oral): 0.5 g/kg
LD50 (rat, skin): 4.0 g/kg

storage

Benzyl benzoate is stable when stored in tight, well-filled, lightresistant containers. Exposure to excessive heat (above 408℃) should be avoided.

Incompatibilities

Benzyl benzoate is incompatible with alkalis and oxidizing agents.

Regulatory Status

Included in the FDA Inactive Ingredients Database (IM injections and oral capsules). Included, as an active ingredient, in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Benzyl benzoate Preparation Products And Raw materials

Raw materials

Preparation Products


Benzyl benzoate Suppliers

Global( 333)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1659 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 sales@frappschem.com China 887 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 894 55
Meihua Biological Technology Co.,Ltd
15175972705
031145896235 sales@hbmeihua.cn CHINA 215 58
Hubei Jusheng Technology Co.,Ltd.
86-155-27864001
peter@hubeijusheng.com CHINA 18004 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4525 58

View Lastest Price from Benzyl benzoate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-17 Benzyl benzoate
120-51-4
US $1.00 / kg 1 g 99% 100KG career henan chemical co
2018-05-25 benzyl benzoate
120-51-4
US $10.00 / KG 10G 99% 1000kg Meihua Biological Technology Co.,Ltd

Benzyl benzoate Spectrum


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