ChemicalBook >> CAS DataBase List >>CHEMBRDG-BB 5280909
CHEMBRDG-BB 5280909
- CAS No.
- 89159-60-4
- Chemical Name:
- CHEMBRDG-BB 5280909
- Synonyms
- ML-354;CHEMBRDG-BB 5280909;1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol;1H-Indole-2-methanol, 1-methyl-5-nitro-3-phenyl-;(1-METHYL-5-NITRO-3-PHENYL-1H-INDOL-2-YL)METHANOL;(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol(SALTDATA: FREE)
- CBNumber:
- CB9163102
- Molecular Formula:
- C16H14N2O3
- Molecular Weight:
- 282.29
- MDL Number:
- MFCD00593702
- MOL File:
- 89159-60-4.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 178-179 °C(Solv: 1,4-dioxane (123-91-1)) |
|---|---|
| Boiling point | 544.0±50.0 °C(Predicted) |
| Density | 1.29±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | ≤2mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide |
| form | powder |
| pka | 14.47±0.10(Predicted) |
| color | white to beige |
CHEMBRDG-BB 5280909 price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19120 | ML-354 ≥95% | 89159-60-4 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19120 | ML-354 ≥95% | 89159-60-4 | 5mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 19120 | ML-354 ≥95% | 89159-60-4 | 10mg | $146 | 2024-03-01 | Buy |
| Cayman Chemical | 19120 | ML-354 ≥95% | 89159-60-4 | 25mg | $343 | 2024-03-01 | Buy |
| Tocris | 5387 | ML354 ≥98%(HPLC) | 89159-60-4 | 10 | $149 | 2021-12-16 | Buy |
CHEMBRDG-BB 5280909 Chemical Properties,Uses,Production
Description
ML-354 is an indole-based, proteinase-activated receptor 4 (PAR4) antagonist (IC50 = 140 nM) that exhibits 71-fold selectivity for PAR4 over PAR1 (IC50 = 10 μM) in isolated human platelets.
Uses
ML-354 is a selective protease activated receptor 4 ( PAR-4) antagonist used for its antithrombotic effects.
Biochem/physiol Actions
ML354 is a potent and selective PAR4 (protease activated receptor-4) antagonist.
IC 50
140 nm
storage
Store at -20°C
References
[1]. wen, w., young, s., duvernay, m., schulte, m., nance, k., & melancon, b. et al. substituted indoles as selective protease activated receptor 4 (par-4) antagonists: discovery and sar of ml354. bioorganic & medicinal chemistry letters. 2014; 24(19): 4708-4713.
CHEMBRDG-BB 5280909 Preparation Products And Raw materials
Raw materials
Preparation Products
CHEMBRDG-BB 5280909 Suppliers
Global( 33)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 | qzhang@aikonchem.com | China | 15527 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
89159-60-4(CHEMBRDG-BB 5280909)Related Search:
CHEMBRDG-BB 5280909
(1-METHYL-5-NITRO-3-PHENYL-1H-INDOL-2-YL)METHANOL
(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol(SALTDATA: FREE)
ML-354
1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol
1H-Indole-2-methanol, 1-methyl-5-nitro-3-phenyl-
89159-60-4