CAMPESTEROL
- CAS No.
- 474-62-4
- Chemical Name:
- CAMPESTEROL
- Synonyms
- Campesterin;Ergost-5-en-3-ol;24α-methyl Cholesterol;(24R)-Ergost-5-en-3β-ol;C01789;CAMPESTROL;CAMPESTEROL;Campasterol;Mieyajunsu A;-17-((2R,5R)
- CBNumber:
- CB9168763
- Molecular Formula:
- C28H48O
- Molecular Weight:
- 400.69
- MDL Number:
- MFCD00010475
- MOL File:
- 474-62-4.mol
- MSDS File:
- SDS
| Melting point | 156-160 °C |
|---|---|
| alpha | D23 -33° (22.5 mg in 5 ml chloroform) |
| Boiling point | 463.29°C (rough estimate) |
| Density | 0.98±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5100 (estimate) |
| storage temp. | -20°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly, Sonicated) |
| form | crystalline |
| pka | 15.03±0.70(Predicted) |
| color | white |
| Merck | 13,1736 |
| BRN | 3216975 |
| InChIKey | SGNBVLSWZMBQTH-ZRUUVFCLSA-N |
| LogP | 9.972 (est) |
| FDA UNII | 5L5O665639 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 |
| Hazard Codes | Xn,T |
| Risk Statements | 20/21/22-36/37/38-48/20/22-40-38-22 |
| Safety Statements | 26-36-45-36/37/39-23 |
| RIDADR | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29061990 |
CAMPESTEROL price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C5157 | Campesterol ~65% | 474-62-4 | 1mg | $130 | 2024-03-01 | Buy |
| Sigma-Aldrich | C5157 | Campesterol ~65% | 474-62-4 | 5mg | $360 | 2024-03-01 | Buy |
| Cayman Chemical | 17344 | 24α-methyl Cholesterol ≥95% | 474-62-4 | 1mg | $71 | 2023-06-20 | Buy |
| Cayman Chemical | 17344 | 24α-methyl Cholesterol ≥95% | 474-62-4 | 5mg | $229 | 2023-06-20 | Buy |
| Sigma-Aldrich | C5157 | Campesterol ~65% | 474-62-4 | 10mg | $599 | 2024-03-01 | Buy |
CAMPESTEROL Chemical Properties,Uses,Production
Description
24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.
Chemical Properties
White Solid
Uses
A phytosterol, which may inhibit the intestinal absorption of cholesterol.
Uses
Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.
Definition
ChEBI: Campesterol is a member of phytosterols, a 3beta-sterol, a 3beta-hydroxy-Delta(5)-steroid and a C28-steroid. It has a role as a mouse metabolite. It derives from a hydride of a campestane.
General Description
Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.
Biochem/physiol Actions
Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.
Purification Methods
Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]
CAMPESTEROL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from CAMPESTEROL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-04-04 | Campesterol
474-62-4
|
US $70.00 / KG | 1KG | 98% | 10kg | Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd. | |
 |
2023-02-24 | Campesterol
474-62-4
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2021-10-28 | CAMPESTEROL
474-62-4
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd |
-
- Campesterol
474-62-4
- US $70.00 / KG
- 98%
- Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
-
- Campesterol
474-62-4
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- CAMPESTEROL
474-62-4
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
474-62-4(CAMPESTEROL)Related Search:
1of4