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H-His(Trt)-OH

H-His(Trt)-OH Structure
H-His(Trt)-OH structure
CAS No.
35146-32-8
Chemical Name:
H-His(Trt)-OH
Synonyms
His(Trt);L-His(Trt);H-HIS(TRT)-OH;L-His(Trt)-OH;L-His(Trt)·H2O;H-L-HIS(TRT)-OH;H-HIS(T-TRT)-OH;H-HIS(1-TRT)-OH;H-His(tau-Trt)-OH;HISTIDINE(1-TRT)-OH
CBNumber:
CB9185713
Molecular Formula:
C25H23N3O2
Molecular Weight:
397.47
MDL Number:
MFCD00153444
MOL File:
35146-32-8.mol
MSDS File:
SDS
Last updated:2023-10-25 11:20:55
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H-His(Trt)-OH Properties

Melting point 210℃
Boiling point 584.8±50.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
pka 1.78±0.10(Predicted)
form Solid
InChI InChI=1S/C25H23N3O2/c26-23(24(29)30)16-22-17-28(18-27-22)25(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-15,17-18,23H,16,26H2,(H,29,30)/t23-/m0/s1
InChIKey BSZQZNOAYQCQFZ-QHCPKHFHSA-N
SMILES C(O)(=O)[C@H](CC1N=CN(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C=1)N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
F  10
NFPA 704
1
0 0

H-His(Trt)-OH price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H62779 1-Trityl-L-histidine, 98% 35146-32-8 1g $48.65 2024-03-01 Buy
Alfa Aesar H62779 1-Trityl-L-histidine, 98% 35146-32-8 5g $171.65 2024-03-01 Buy
TRC T808775 1-(Triphenylmethyl)-L-histidine 35146-32-8 10g $120 2021-12-16 Buy
Usbiological 285606 Nim-Trityl-histidine 35146-32-8 2g $333 2021-12-16 Buy
American Custom Chemicals Corporation AAA0002849 H-HIS(TRT)-OH 95.00% 35146-32-8 1G $151.83 2021-12-16 Buy
Product number Packaging Price Buy
H62779 1g $48.65 Buy
H62779 5g $171.65 Buy
T808775 10g $120 Buy
285606 2g $333 Buy
AAA0002849 1G $151.83 Buy

H-His(Trt)-OH Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

1-(Triphenylmethyl)-L-histidine is a reactant in the synthesis of falcitidin acyl tetrapeptides as antimalarial agent.

Preparation

The amino acid N(im)-trityl-D-histidine was dissolved in dichloromethane, followed by the addition of triethylamine and trimethylsilyl chloride (3.5 equivalents). After 2 hours of gentle reflux, the mixture was ready to be used for in situ coupling to the anhydride of the carboxylic acid. Thus, isovaleric acid was separately dissolved in THF and maintained at -20 ℃ using an ice-salt bath. N-methyl morpholine (1.2 equivalents) was added, followed by the addition of ethyl chloroformate (1.0 equivalent). After 15-20 minutes at -20 ℃, the bis-TMS amino acid reaction mixture was added directly to the anhydride solution and left stirring at room temperature overnight. After 8 hours, the reaction mixture was concentrated in vacuo. Finally, H-His(Trt)-OH was obtained after purification.H-HIS(TRT)-OH

Definition

H-His(Trt)-OH, also known as 1-(Triphenylmethyl)-L-histidine, is a histidine derivative. It can be obtained by removing fmoc group protection from Fmoc-His(Trt)-OH. L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the histaminergic system.

H-His(Trt)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

Fmoc-His(Trt)-OH

H-His(Trt)-OH Suppliers

Global( 179)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8618980456393 daisy@enlaibio.com China 1369 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Sichuan Jiaying Lai Technology Co.,LTD 		18716376478 ycling@enlaibio.com CHINA 302 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
Supplier Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
GenicBio Limited 		58
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Sichuan Jiaying Lai Technology Co.,LTD 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58

View Lastest Price from H-His(Trt)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-L-His(trt)-OH pictures 2024-04-23 H-L-His(trt)-OH
35146-32-8
 US $0.00-0.00 / kg 1kg 98%;99% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
H-His(trt)-OH pictures 2020-01-06 H-His(trt)-OH
35146-32-8
 US $1.00 / g 1g 98% 100KG Sichuan Jiaying Lai Technology Co.,LTD
H-HIS(TRT)-OH pictures 2019-07-06 H-HIS(TRT)-OH
35146-32-8
 US $1.00 / KG 1KG 98% 1kg,5kg,100kg Career Henan Chemical Co
  • H-L-His(trt)-OH pictures
  • H-L-His(trt)-OH
    35146-32-8
  • US $0.00-0.00 / kg
  • 98%;99%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • H-His(trt)-OH pictures
  • H-His(trt)-OH
    35146-32-8
  • US $1.00 / g
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD

35146-32-8(H-His(Trt)-OH)Related Search:

Methyl L-histidinate dihydrochloride H-HIS(BZL)-OH 3-METHYL-L-HISTIDINE H-His(Trt)-OMe · HCl 3,5-DIIODO-D-TYROSINE HYDROCHLORIDE
Fmoc-His(Trt)-OH N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester H-His(Trt)-OH Boc-His(Trt)-OH TRT-OH
N-Boc-S-Trityl-L-cysteine N-Boc-N'-trityl-L-glutamine N-FMOC-GLY(TRT)-OH Z-GLN(TRT)-OH,Z-GLUTAMINE(TRT)-OH FMOC-D-PEN(TRT)-OH
Z-ASN(TRT)-OH Fmoc-Asn(Trt)-OH H-GLN(TRT)-OH

1of4

N-τ-Trityl-L-histidine 1-(Triphenylmethyl)-L-histidine L-His(Trt)·H2O L-His(Trt)-OH Nim-Trityl-histidine≥ 98% (HPLC) 1-Trityl-L-histidine, 98% H-L-HIS(TRT)-OH HISTIDINE(1-TRT)-OH H-HIS(1-TRT)-OH H-HIS(T-TRT)-OH H-HIS(TRT)-OH RARECHEM AL BE 1480 N-IM-TRITYL-HISTIDINE N-IM-TRITYL-L-HISTIDINE N-TAU-TRITYL-L-HISTIDINE His(Trt) N-TRITYL-L-HISTIDINE H-His(tau-Trt)-OH (2S)-2-amino-3-(1-tritylimidazol-4-yl)propanoicacid (2S)-2-amino-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoic acid (2S)-2-amino-3-[1-(triphenylmethyl)-4-imidazolyl]propanoic acid L-His(Trt) (2S)-2-ammonio-3-(1-trityl-1H-imidazol-4-yl)propanoate (S)-2-Amino-3-(1-trityl-1H-imidazol-4-yl)propanoicacid L-Histidine, 1-(triphenylmethyl)- (2S)-2-amino-3-(1-tritylimidazol-4-yl)propanoicaci H-HIS(TRT)-OH USP/EP/BP 35146-32-8 C25H23N3O2 Histidine Peptide Synthesis Specialty Synthesis Amino Acid Derivatives Histidine [His, H] Amino Acids and Derivatives Amino Acid Derivatives Histidine Peptide Synthesis