Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Fumed Silica

Fumed Silica

Fumed Silica Structure
Fumed Silica structure
CAS No.
112945-52-5
Chemical Name:
Fumed Silica
Synonyms
COLLOIDAL SILICA;SAND;ludox;SILICA GEL 60;Nanometer;dicalite;SILICA GEL DESICCANT;IATROBEADS;SILICA STANDARD;SILICA GEL ORANGE
CBNumber:
CB9199390
Molecular Formula:
O2Si
Molecular Weight:
60.08
MDL Number:
MFCD01778716
MOL File:
112945-52-5.mol
MSDS File:
SDS
Last updated:2024-04-25 10:45:11
Request For Quotation

Fumed Silica Properties

Melting point >1600°C
Density 2.3 lb/cu.ft at 25 °C (bulk density)(lit.)
refractive index n20/D 1.46(lit.)
solubility Practically insoluble in organic solvents, water, and acids, except hydrofluoric acid; soluble in hot solutions of alkali hydroxide. Forms a colloidal dispersion with water. For Aerosil, solubility in water is 150 mg/L at 258℃ (pH 7).
form powder
Specific Gravity 2.2
Hydrolytic Sensitivity 5: forms reversible hydrate
CAS DataBase Reference 112945-52-5(CAS DataBase Reference)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms nanometer
EPA Substance Registry System Silica, amorphous, fumed, cryst.-free (112945-52-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H335-H350-H315-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Safety Statements  24/25
WGK Germany  2
RTECS  VV7310000
TSCA  Yes
HS Code  28112290

Fumed Silica price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 381276 Silica 99.8% 112945-52-5 100g $45.1 2024-03-01 Buy
Sigma-Aldrich 381276 Silica 99.8% 112945-52-5 500g $91.6 2024-03-01 Buy
Strem Chemicals 14-6100 High Surface area Silica nanoparticles, Large, particle size ~900-1000 nm, surface area ~700 m2/g, (KCC-1 L1) 112945-52-5 1g $60 2024-03-01 Buy
Strem Chemicals 14-6100 High Surface area Silica nanoparticles, Large, particle size ~900-1000 nm, surface area ~700 m2/g, (KCC-1 L1) 112945-52-5 5g $233 2024-03-01 Buy
Sigma-Aldrich S5505 Silica, fumed powder, 0.2-0.3 μm avg. part. size (aggregate) 112945-52-5 100g $55.7 2024-03-01 Buy
Product number Packaging Price Buy
381276 100g $45.1 Buy
381276 500g $91.6 Buy
14-6100 1g $60 Buy
14-6100 5g $233 Buy
S5505 100g $55.7 Buy

Fumed Silica Chemical Properties,Uses,Production

Chemical Properties

Colloidal silicon dioxide is a submicroscopic fumed silica with a particle size of about 15 nm. It is a light, loose, bluish-white-colored, odorless, tasteless, amorphous powder.

Chemical Properties

Amorphous silica, the noncrystalline form of SiO2, is a transparent to gray, odorless, amorphous powder

Uses

Synthetic Amorphous Silica has interesting thickening and thixotropic properties, and an enormous external surface area. It is produced by a vapor phase hydrolysis process using chlorosilanes or substituted silanes such as, silicon tetrachloride in a flame of hydrogen and oxygen. This material is formed and collected in a dry state. This product contains no detectable crystalline silica.

Production Methods

Colloidal silicon dioxide is prepared by the flame hydrolysis of chlorosilanes, such as silicon tetrachloride, at 18008℃ using a hydrogen–oxygen flame. Rapid cooling from the molten state during manufacture causes the product to remain amorphous.

Definition

ChEBI: Silicon dioxide is a silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.

General Description

Fumed silica may be synthesized by high temperature hydrolysis of SiCl4 in O2(N2)/H2 flame. It is amorphous in nature and possesses very high specific area. The micro droplets of amorphous silica fuse into a branch and form a chain like agglomerate.

Pharmaceutical Applications

Colloidal silicon dioxide is widely used in pharmaceuticals, cosmetics, and food products. Its small particle size and large specific surface area give it desirable flow characteristics that are exploited to improve the flow properties of dry powders in a number of processes such as tableting and capsule filling.
Colloidal silicon dioxide is also used to stabilize emulsions and as a thixotropic thickening and suspending agent in gels and semisolid preparations. With other ingredients of similar refractive index, transparent gels may be formed. The degree of viscosity increase depends on the polarity of the liquid (polar liquids generally require a greater concentration of colloidal silicon dioxide than nonpolar liquids). Viscosity is largely independent of temperature. However, changes to the pH of a system may affect the viscosity1.
In aerosols, other than those for inhalation, colloidal silicon dioxide is used to promote particulate suspension, eliminate hard settling, and minimize the clogging of spray nozzles. Colloidal silicon dioxide is also used as a tablet disintegrant and as an adsorbent dispersing agent for liquids in powders. Colloidal silicon dioxide is frequently added to suppository formulations containing lipophilic excipients to increase viscosity, prevent sedimentation during molding, and decrease the release rate. Colloidal silicon dioxide is also used as an adsorbent during the preparation of wax microspheres; as a thickening agent for topical preparations; and has been used to aid the freeze-drying of nanocapsules and nanosphere suspensions.

Safety Profile

Poison by intraperitoneal, intravenous, and intratracheal routes. Moderately toxic by ingestion. An inhalation hazard. Much less toxic than crystalhe forms. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. Does not cause silicosis. See also other silica entries

Safety

Colloidal silicon dioxide is widely used in oral and topical pharmaceutical products and is generally regarded as an essentially nontoxic and nonirritant excipient. However, intraperitoneal and subcutaneous injection may produce local tissue reactions and/or granulomas. Colloidal silicon dioxide should therefore not be administered parenterally.
LD50 (rat, IV): 0.015 g/kg
LD50 (rat, oral): 3.16 g/kg

Potential Exposure

Amorphous fumed silica is used as a mineral, natural or synthetic fiber. A potential danger to those involved in the production and handling of fumed silica for paint pigments or catalysts. Diatomaceous earth is used in clarifying liquids, in manufacture of fire brick and heat insulators; used as a filtering agent; as a filler in construction materials; pesticides, paints, and varnishes. A potential danger to those involved in mining of diatomaceous earth or fabrication of products there from.

storage

Colloidal silicon dioxide is hygroscopic but adsorbs large quantities of water without liquefying. When used in aqueous systems at a pH 0–7.5, colloidal silicon dioxide is effective in increasing the viscosity of a system. However, at a pH greater than 7.5 the viscosityincreasing properties of colloidal silicon dioxide are reduced; and at a pH greater than 10.7 this ability is lost entirely since the silicon dioxide dissolves to form silicates. Colloidal silicon dioxide powder should be stored in a well-closed container.

Purification Methods

Purification of silica for high technology applications uses isopiestic vapour distillation from concentrated volatile acids and is absorbed in high purity water. The impurities remain behind. Preliminary cleaning to remove surface contaminants uses dip etching in HF or a mixture of HCl, H2O2 and deionised water [Phelan & Powell Analyst 109 1299 1984].

Incompatibilities

Silica, amorphous is a noncombustible solid. Generally unreactive chemically. Incompatible with fluorine, oxygen difluoride, chlorine trifluoride. Soluble in molten alkalis and reacts with most metallic oxides at high temperature.

Incompatibilities

Incompatible with diethylstilbestrol preparations.

Waste Disposal

Sanitary landfill.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (oral capsules, suspensions, and tablets; transdermal, rectal, and vaginal preparations). Also approved by the FDA as a food additive and for food contact. Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Nonmedicinal Ingredients.

Fumed Silica Preparation Products And Raw materials

Raw materials

Sulfuric acid

Preparation Products

piling adhesive YH-891 1-OCTADECENE Silicon carbide Magnesium fluorosilicate LEAD SILICOCHROMATE
Hexafluorosilicic acid Premixing agent Porcelain glaze,industrial Sodium silicate SILICA
Sodium fluorosilicate SODIUM METASILICATE PENTAHYDRATE Sodium fluoride Potassium silicate DICALCIUM PHOSPHATE DIHYDRATE

1of3

Fumed Silica Suppliers

Global( 326)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618740459177 sarah@tnjone.com China 893 58
Yujiang Chemical (Shandong) Co.,Ltd. 		+86-17736087130 +86-18633844644 catherine@yjchem.com.cn China 147 58
Hangzhou Bayee Chemical Co., Ltd. 		0086-571-86990109 rachelhoo@bayeechem.com China 104 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
Xiamen AmoyChem Co., Ltd 		+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shandong chuangyingchemical Co., Ltd. 		18853181302 sale@chuangyingchem.com CHINA 5909 58
Shanghai Longyu Biotechnology Co., Ltd. 		+8615821988213 info@longyupharma.com China 2531 58
Supplier Advantage
Henan Bao Enluo International TradeCo.，LTD 		58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		58
Yujiang Chemical (Shandong) Co.,Ltd. 		58
Hangzhou Bayee Chemical Co., Ltd. 		55
Henan Tianfu Chemical Co.,Ltd. 		55
Hefei TNJ Chemical Industry Co.,Ltd. 		55
Xiamen AmoyChem Co., Ltd 		58
Hubei xin bonus chemical co. LTD 		58
Shandong chuangyingchemical Co., Ltd. 		58
Shanghai Longyu Biotechnology Co., Ltd. 		58

Related articles

View Lastest Price from Fumed Silica manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fumed silica pictures 2024-04-24 Fumed silica
112945-52-5
 US $0.00 / kg 1kg 98% 20T Yujiang Chemical (Shandong) Co.,Ltd.
Silica, fumed pictures 2024-04-24 Silica, fumed
112945-52-5
 US $9552.00 / Tons 10Tons 99.99% 100Tons Hebei Dangtong Import and export Co LTD
Colloidal Silicon Dioxide pictures 2024-04-22 Colloidal Silicon Dioxide
112945-52-5
 US $0.00 / kg 1kg 99% 10000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
  • Fumed silica pictures
  • Fumed silica
    112945-52-5
  • US $0.00 / kg
  • 98%
  • Yujiang Chemical (Shandong) Co.,Ltd.
  • Silica, fumed pictures
  • Silica, fumed
    112945-52-5
  • US $9552.00 / Tons
  • 99.99%
  • Hebei Dangtong Import and export Co LTD

112945-52-5(Fumed Silica)Related Search:

Celite Chlorine dioxide Benzoyl peroxide Quartz SILICA
Carbon dioxide Sulfurous Acid Zirconium dioxide Rutile Silicon dioxide
GUIJIAOBAN Silica, fumed Silica gel Thiourea dioxide Thin-layer chromatography silica gel
ZHUCENGCENGXIGUIJIAO GF254: 20*20CM analysis board Chromatography silica gel Silica Gel 60

1of4

acticel SILICA GEL 7G SILICA GEL 8-20 MESH SILICA GEL 12-28 MESH SILICA GEL 100 SILICA GEL 30 SILICA GEL 60 G WATER-IMPREGNATED SILICA GEL WAKOSIL(R) C-200 WAKOSIL(R) C-300 WAKOSIL(R) 5SIL WAKOSIL(R) 5SIL-120 WAKOSIL(R) 7SIL-120 WAKOSIL(R) 25SIL WAKOSIL(R) 40SIL WAKOGEL(R) B-0 WAKOGEL(R) B-0 F WAKOGEL(R) B-10 WAKOGEL(R) B-5 WAKOGEL(R) B-5F WAKOGEL(R) B-5 FM WAKOGEL(R) C-100 WAKOGEL(R) C-200 WAKOGEL(R) C-200E WAKOGEL(R) C-300 WAKOGEL(R) C-300E WAKOGEL(R) C-300HG WAKOGEL(R) C-400HG WAKOGEL(R) C-500HG WAKOGEL(R) DX WAKOGEL(R) FC-40 WAKOGEL(R) FC-40FM WAKOGEL(R) G WAKOGEL(R) LP-20 WAKOGEL(R) LP-40 WAKOGEL(R) LP-60 WAKOGEL(R) Q-12 WAKOGEL(R) Q-22 WAKOGEL(R) Q-23 WAKOGEL(R) Q-50 WAKOGEL(R) Q-63 WAKOGEL(R) S-1 THE(R) DESICCANT diketosilane Silica,Silica, fumed, Silica, Silicic anhydride, Silicon dioxide amorphous, Silicon dioxide Silica, fuMed powder, 0.007 MuM Silica, fuMed powder, 0.2-0.3 MuM avg. part. size (aggregate) Monodisperse silica microspheres Silica, powder, 200 Mesh Aerosil R 8200 hydrophobic fumed silica (SiO2) Aerosil380 Hydrophilic fumed silica (SiO2) AerosilMOX 170 Hydrophilic fumed mixed oxide (SiO2+Al2O3) HDK N20 hydrophobic fumed silica (SiO2) HDK T40 HYDROPHILIC PYROGENIC SILICA Hydrophilic fumed silica hydrophilic (SiO2) hydrophobic fumed silica (SiO2) Liquid - phase silica , hydrophobic (SiO2) HIGHSURFACEAREASILICANANOPARTICLES