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2-Nitroacetophenone

CAS No.
577-59-3
Chemical Name:
2-Nitroacetophenone
Synonyms
1-(2-nitrophenyl)ethanone;NSC 3641;AKOS 233-65;AURORA 14018;AKOS BBS-00003220;2-Nitroacetophene;2'-Nitroacetophne;2-NITROACETOPHENONE;O-NITROACETOPHENONE;2'-NITROACETOPHENONE
CBNumber:
CB9208092
Molecular Formula:
C8H7NO3
Molecular Weight:
165.15
MDL Number:
MFCD00007144
MOL File:
577-59-3.mol
MSDS File:
SDS
Last updated:2024-04-24 17:21:45

2-Nitroacetophenone Properties

Melting point 76-78 °C(lit.)
Boiling point 202 °C(lit.)
Density 1.23
refractive index n20/D 1.55(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Ethyl Acetate
form Solid
color Brown
Water Solubility Insoluble
FreezingPoint 24.0 to 28.0 ℃
BRN 1102322
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 577-59-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 52L53K4X3O
NIST Chemistry Reference Ethanone, 1-(2-nitrophenyl)-(577-59-3)
EPA Substance Registry System 2-Nitroacetophenone (577-59-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  AM9625000
Hazard Note  Harmful
TSCA  Yes
HS Code  29147090
NFPA 704
1 0

2-Nitroacetophenone price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N9209 2′-Nitroacetophenone 95% 577-59-3 10g $28.3 2024-03-01 Buy
Sigma-Aldrich N9209 2′-Nitroacetophenone 95% 577-59-3 1g $22.8 2022-05-15 Buy
TCI Chemical N0110 2'-Nitroacetophenone >96.0%(GC) 577-59-3 5g $20 2024-03-01 Buy
TCI Chemical N0110 2'-Nitroacetophenone >96.0%(GC) 577-59-3 25g $55 2024-03-01 Buy
Alfa Aesar A13208 2'-Nitroacetophenone, 97% 577-59-3 10g $79.65 2024-03-01 Buy
Product number Packaging Price Buy
N9209 10g $28.3 Buy
N9209 1g $22.8 Buy
N0110 5g $20 Buy
N0110 25g $55 Buy
A13208 10g $79.65 Buy

2-Nitroacetophenone Chemical Properties,Uses,Production

Chemical Properties

yellow-green liquid or crystals. Soluble in alcohol, ether and chloroform, slightly soluble in water.

Uses

2'-Nitroacetophenone is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. It is also used as a synthetic reagent. It is the sensitizer which can be used as pharmaceutical intermediates.

Uses

2''-Nitroacetophenone (cas# 577-59-3) is a compound useful in organic synthesis. It is also used as an intermediate for photosensitive materials.?

Preparation

o-Nitroacetophenone is synthesized from o-nitroethylbenzene by oxidation. Add o-nitroethylbenzene, decanoic acid and initiator azobisisobutyronitrile into the reaction tower, and at the same time slowly pass air into the tower, keep the pressure at 0.3-0.8MPa, and control the oxidation at 120-130°C to generate 2-Nitroacetophenone.

Synthesis Reference(s)

The Journal of Organic Chemistry, 43, p. 3631, 1978 DOI: 10.1021/jo00412a058
Journal of the American Chemical Society, 105, p. 943, 1983 DOI: 10.1021/ja00342a050
Synthesis, p. 228, 1988 DOI: 10.1055/s-1988-27522

General Description

Clear yellow liquid. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire Hazard

2-Nitroacetophenone is combustible.

98-86-2
577-59-3
Synthesis of 2-Nitroacetophenone from Acetophenone
Global( 341)Suppliers
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Hebei Mojin Biotechnology Co., Ltd
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8485655694 sales@alchempharmtech.com United States 63711 58

View Lastest Price from 2-Nitroacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Nitroacetophenone pictures 2024-04-24 2-Nitroacetophenone
577-59-3
US $10.00 / kg 1kg 99.8% 10000ton Ouhuang Engineering Materials (Hubei) Co., Ltd
2-Nitroacetophenone pictures 2023-12-24 2-Nitroacetophenone
577-59-3
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2-Nitroacetophenone pictures 2023-06-28 2-Nitroacetophenone
577-59-3
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Neighboring nitrobenzene ethyl ketone 2’-nitro-acetophenon AKOS BBS-00003220 2'-NITROACETOPHENONE 2-NITROACETOPHENONE LABOTEST-BB LT01895210 AURORA 14018 ETHANONE, 1-(2-NITROPHENYL)- 1-(2-nitrophenyl)-ethanon 2-Nitroacetophenone,97% 1-(2-nitrophenyl)-Ethanone2-Nitroacetophenone 2-nitro-1-phenylethanone 2-Nitroacetophene 1-Acetyl-2-nitrobenzene o-Nitroacetophenone,95% 1-(2-Nitrophenyl)ethan-1-one, 2-Acetylnitrobenzene o-Nitroacetophenone, 95% 2.5GR Methyl-o-nitrophenylketone NSC 3641 o-nitroacetonphenone 2-p-nitroacetophenone 2'-Nitroacetophenone, 95+% 2-acetylnitrobenzene Acetophenone, 2'-nitro- Methyl 2-nitrophenyl ketone methyl2-nitrophenylketone o-Acetylnitrobenzene o-Nitro(acetyl)benzene o-nitrophenyl methyl ketone O-NITROACETOPHENONE AKOS 233-65 2'-Nitroacetophenone> 1-(2-nitrophenyl)ethanone 2'-Nitroacetophne 2'-Nitroacetophenone 577-59-3 CH3COC6H4NO2 NO2C6H4COCH3 C8H7BNO3 KETONE Building Blocks C7 to C8 Carbonyl Compounds Ketones Organic Building Blocks Aromatic Acetophenones & Derivatives (substituted) Aromatics Miscellaneous Reagents C7 to C8 Carbonyl Compounds Ketones pharmaceutical intermediates Carbonyl Compounds