Monoclonal Anti-β-Tubulin
- CAS No.
- Chemical Name:
- Monoclonal Anti-β-Tubulin
- Synonyms
- Monoclonal Anti-β-Tubulin;Monoclonal Anti-β-Tubulin-Cy3 antibody produced in mouse;Monoclonal Anti-β-Tubulin-FITC antibody produced in mouse
- CBNumber:
- CB92091678
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Hazard Codes | Xn |
---|---|
Risk Statements | 21/22 |
Safety Statements | 23-24/25-36/37 |
Monoclonal Anti-β-Tubulin Chemical Properties,Uses,Production
Uses
Monoclonal Anti-β-Tubulin-Cy3 antibody produced in mouse has been used in:
- immunohistochemical assays
- immunofluorescence
- western blotting
- immunocytochemistry
- immunoblotting
- immunostaining
General Description
β-Tubulin belongs to the subfamily of tubulins. It has two β-sheets enclosed by α-helices. It also contains an N-terminal domain with the guanine nucleotide-binding region, an intermediate domain with taxol-binding site and a C-terminal domain, which has the binding surface for molecular motor proteins. Human β-tubulin consists of seven isoforms (βI (class I), βII (class II), βIII (class III), βIVa (class IVa), βIVb (class IVb), βV (class V), and βVI (class VI)). TUBB1 (tubulin beta class I) is located on human chromosome 6p21.33.(10)
Biochem/physiol Actions
Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement and in the cytoskeleton. Mutation in the β-tubulin gene leads to various neuronal migration disorders such as lissencephaly, pachygyria and polymicrogyria malformations.
Monoclonal Anti-β-Tubulin Preparation Products And Raw materials
Raw materials
Preparation Products
Monoclonal Anti-β-Tubulin Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |