Anti-ATG6, Anti-BECN1, Anti-Coiled-coil myosin-like BCL2-interacting protein, Anti-GT197, Anti-VPS30
- CAS No.
- Chemical Name:
- Anti-ATG6, Anti-BECN1, Anti-Coiled-coil myosin-like BCL2-interacting protein, Anti-GT197, Anti-VPS30
- Synonyms
- Anti-ATG6;Anti-VPS30;Anti-GT197;Anti-BECN1;Anti-beclin1;Anti-ATG6 autophagy related 6 homolog;Anti-Beclin 1 antibody produced in rabbit;Anti-BECN1, (N-terminal) antibody produced in rabbit;Anti-Beclin 1 (N-terminal) antibody produced in rabbit;Anti-Beclin 1 (coiled-coil, moesin-like BCL2 interacting protein)
- CBNumber:
- CB92094705
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD09753851
- MOL File:
- Mol file
Anti-ATG6, Anti-BECN1, Anti-Coiled-coil myosin-like BCL2-interacting protein, Anti-GT197, Anti-VPS30 price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SAB1306484 | ANTI-BECLIN 1 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μl | $481 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB1305637 | ANTI-BECLIN 1 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 400μl | $508 | 2024-03-01 | Buy | |
Sigma-Aldrich | PRS3613 | Anti-Beclin-1 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 100μg | $478 | 2024-03-01 | Buy | |
Sigma-Aldrich | B6061 | Anti-Beclin 1 (N-terminal) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 200μL | $235.2 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB1306271 | ANTI-BECLIN 1 antibody produced in rabbit purified immunoglobulin, buffered aqueous solution | 400μl | $461 | 2023-01-07 | Buy |
Anti-ATG6, Anti-BECN1, Anti-Coiled-coil myosin-like BCL2-interacting protein, Anti-GT197, Anti-VPS30 Chemical Properties,Uses,Production
Uses
Anti-Beclin 1 (N-terminal) antibody produced in rabbit has been used in:
- immunofluorescent staining
- immunoblotting
- immunohistochemistry
- immunoprecipitation
General Description
Beclin 1 (BECN1) or GT197 is a tumor suppressor gene. It is a Bcl-2 (B-cell lymphoma 2) interacting protein and is the mammalian ortholog of yeast Atg6/Vps30. It is a 450 amino-acid protein having three domains. The gene encoding BECN1 is localized on human chromosome 17q21.
Biochem/physiol Actions
Beclin 1 (BECN1) is able to complement the autophagy deficiency of yeast lacking autophagy-related gene 6 (Atg6) and restores autophagy in human MCF7 breast carcinoma cells. Beclin 1 plays a major role in the early development of embryo. It also serves as a haplo-insufficient tumor-suppressor gene. Heterozygous Beclin 1 mutant mice have increased spontaneous tumorigenesis. Beclin 1 is monoallelically deleted in a high percentage of sporadic human breast, ovarian and prostate carcinomas and is expressed at reduced levels in those tumors. In human brains BECN1 decreases in an age-dependent fashion, possibly leading to a reduction of autophagic activity during aging, which may contribute to the accumulation of mutant Huntingtin and the age-delayed disease onset of Huntington disease.
Anti-ATG6, Anti-BECN1, Anti-Coiled-coil myosin-like BCL2-interacting protein, Anti-GT197, Anti-VPS30 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-ATG6, Anti-BECN1, Anti-Coiled-coil myosin-like BCL2-interacting protein, Anti-GT197, Anti-VPS30 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |