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FPL 64176

CAS No.
120934-96-5
Chemical Name:
FPL 64176
Synonyms
FPL 64176;ARC-64176;MDMWHKZANMNXTF-UHFFFAOYSA-N;FPL 64176 >94% POTENT CA2+ CHANNEL (;Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate;4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester;2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester;Ca2+ channels,FPL64176,inhibit,Inhibitor,Calcium Channel,Ca channels,FPL-64176;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER
CBNumber:
CB9210534
Molecular Formula:
C22H21NO3
Molecular Weight:
347.41
MDL Number:
MFCD00274043
MOL File:
120934-96-5.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59

FPL 64176 Properties

storage temp. 2-8°C
solubility DMSO: 10 mg/mL Solutions should be freshly prepared.
form solid
color tan
FDA UNII UU89L306PO

SAFETY

Risk and Safety Statements

WGK Germany  3

FPL 64176 price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F131 FPL 64176 ≥98% (HPLC), powder 120934-96-5 25mg $222 2024-03-01 Buy
Sigma-Aldrich F131 FPL 64176 ≥98% (HPLC), powder 120934-96-5 100mg $1200 2023-01-07 Buy
Cayman Chemical 20122 FPL 64176 ≥98% 120934-96-5 1mg $32 2024-03-01 Buy
Cayman Chemical 20122 FPL 64176 ≥98% 120934-96-5 5mg $70 2024-03-01 Buy
Cayman Chemical 20122 FPL 64176 ≥98% 120934-96-5 10mg $122 2024-03-01 Buy
Product number Packaging Price Buy
F131 25mg $222 Buy
F131 100mg $1200 Buy
20122 1mg $32 Buy
20122 5mg $70 Buy
20122 10mg $122 Buy

FPL 64176 Chemical Properties,Uses,Production

Uses

FPL-64176 is a nondihydropyridine Ca2+ channel activator.

Definition

ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester.

Biological Activity

Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria.

Biochem/physiol Actions

Potent Ca2+ channel (L-type) activator.

storage

Store at RT

FPL 64176 Preparation Products And Raw materials

Raw materials

Preparation Products

FPL 64176 Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Aikon International Limited 025-58851090 13611564524 lwan@aikonchem.com China 15952 58
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
FPL 64176 2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER 2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER 2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester 4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester FPL 64176 >94% POTENT CA2+ CHANNEL ( MDMWHKZANMNXTF-UHFFFAOYSA-N ARC-64176 1H-Pyrrole-3-carboxylic acid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate Ca2+ channels,FPL64176,inhibit,Inhibitor,Calcium Channel,Ca channels,FPL-64176 120934-96-5 BioChemical Calcium Channel Modulators Cell Biology Cell Signaling and Neuroscience Inhibitors and Activators Ion Channels Voltage-gated Ion Channels Calcium channel