ChemicalBook >> CAS DataBase List >>SULINDAC SULFIDE
SULINDAC SULFIDE
- CAS No.
- 49627-27-2
- Chemical Name:
- SULINDAC SULFIDE
- Synonyms
- Einecs 256-403-9;SULINDAC SULPHIDE;(Z)-Sulindac sulfide;cis-Sulindac sulfide;Sulindac USP Related Compound C;Sulindac EP Impurity C (Sulindac Sulfide);Sulindac Impurity 3（Sulindac EP Impurity C）;(Z)-5-FLUORO-2-METHYL-1-[P-(METHYLTHIO)BENZYLIDENE]INDENE-3-ACETIC ACID;(Z)-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-1H-INDEN-3-YLACETIC ACID;Sulindac EP Impurity C (Sulindac USP Related Compound C, Sulindac Sulfide)
- CBNumber:
- CB9211728
- Molecular Formula:
- C20H17FO2S
- Molecular Weight:
- 340.41
- MDL Number:
- MFCD00869764
- MOL File:
- 49627-27-2.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
| Melting point | 189-191°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | DMSO: >22 mg/mL |
| form | solid |
| color | yellow |
| FDA UNII | 6UVA8S2DEY |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xn |
|---|---|
| Risk Statements | 22-42/43-63 |
| WGK Germany | 3 |
| HS Code | 2930902000 |
SULINDAC SULFIDE price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1642031 | Sulindac Related Compound C United States Pharmacopeia (USP) Reference Standard | 49627-27-2 | 20MG | $1300 | 2024-03-01 | Buy |
| Cayman Chemical | 10004387 | Sulindac sulfide ≥98% | 49627-27-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 10004387 | Sulindac sulfide ≥98% | 49627-27-2 | 5mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 10004387 | Sulindac sulfide ≥98% | 49627-27-2 | 10mg | $87 | 2024-03-01 | Buy |
| Cayman Chemical | 10004387 | Sulindac sulfide ≥98% | 49627-27-2 | 25mg | $184 | 2024-03-01 | Buy |
SULINDAC SULFIDE Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.
Uses
An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.
Definition
ChEBI: An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity.
SULINDAC SULFIDE Preparation Products And Raw materials
Raw materials
Preparation Products
SULINDAC SULFIDE Suppliers
Global( 82)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| HANGZHOU LOOP BIOTECH CO., LTD. | 0571-85810519 13396556070 | sales01@looppharm.com | China | 42 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
49627-27-2(SULINDAC SULFIDE)Related Search:
(Z)-5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
(Z)-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-1H-INDEN-3-YLACETIC ACID
5-Fluoro-2-methyl-1-[(Z)-[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid
(Z)-Sulindac sulfide
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylthio)phenyl)methylene)-, (Z)-
Einecs 256-403-9
SULINDAC SULPHIDE
(Z)-5-FLUORO-2-METHYL-1-[P-(METHYLTHIO)BENZYLIDENE]INDENE-3-ACETIC ACID
Sulindac Impurity 3（Sulindac EP Impurity C）
cis-Sulindac sulfide
Sulindac EP Impurity C (Sulindac Sulfide)
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-, (1Z)-
Sulindac Related Compound C ((Z)-2-{5-fluoro-2-methyl-1-[4-(methylthio)benzylidene]-1H-inden-3-yl}a (1642031)
Sulindac USP Related Compound C
(Z)-2-{5-fluoro-2-methyl-1-[4-(methylthio)benzylidene]-1H-inden-3-yl}acetic acid
Sulindac EP Impurity C (Sulindac USP Related Compound C, Sulindac Sulfide)
49627-27-2
Reagents
Cell Signaling and Neuroscience
Cell Biology
BioChemical
G Protein Function
G Proteins and Cyclic Nucleotides
Intermediates & Fine Chemicals
Metabolites
Pharmaceuticals