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DCPIB

DCPIB Structure
DCPIB structure
CAS No.
82749-70-0
Chemical Name:
DCPIB
Synonyms
DCPIB;4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID;4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid;4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid;4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID;Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-;Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO
CBNumber:
CB9215009
Molecular Formula:
C22H28Cl2O4
Molecular Weight:
427.36
MDL Number:
MFCD07783995
MOL File:
82749-70-0.mol
Last updated:2023-06-30 15:45:59
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DCPIB Properties

Boiling point 593.8±50.0 °C(Predicted)
Density 1.262±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility insoluble in H2O; ≥49.8 mg/mL in EtOH; ≥50.8 mg/mL in DMSO
pka 4.53±0.10(Predicted)
form solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H413-H318
Precautionary statements  P280-P305+P351+P338-P310-P264-P270-P301+P310-P321-P330-P405-P501
Hazard Codes  T
Risk Statements  25-41
Safety Statements  26-36/39-45
NFPA 704
0
3 0

DCPIB price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1540 DCPIB ≥98%(HPLC) 82749-70-0 50 $675 2021-12-16 Buy
Tocris 1540 DCPIB ≥98%(HPLC) 82749-70-0 10 $160 2021-12-16 Buy
TRC D195150 DCPIB 82749-70-0 100mg $1105 2021-12-16 Buy
Usbiological 255115 DCPIB 82749-70-0 10mg $403 2021-12-16 Buy
ChemScene CS-0027766 DCPIB 99.81% 82749-70-0 50mg $550 2021-12-16 Buy
Product number Packaging Price Buy
1540 50 $675 Buy
1540 10 $160 Buy
D195150 100mg $1105 Buy
255115 10mg $403 Buy
CS-0027766 50mg $550 Buy

DCPIB Chemical Properties,Uses,Production

Uses

DCPIB is a potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β-cells.

Definition

ChEBI: 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl)oxy]butanoic acid is a member of indanones.

Biological Activity

Potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β -cells (IC 50 ~ 2 μ M) and I Cl,swell in various cardiovascular tissues (IC 50 = 4.1 μ M in CPAE cells); blockade is voltage-independent. Displays minimal inhibition of other Cl - and K + currents (< 10% inhibition at 10 μ M). Inhibits glucose-stimulated insulin secretion in intact β -cells via VSAC inhibition and indirect K ATP channel activation. Reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro .

storage

Store at +4°C

DCPIB Preparation Products And Raw materials

Raw materials

Preparation Products

DCPIB Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Nanjing Doge Biomedical Technology Co., Ltd 		+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Zhengzhou HSH Science & Technology Co., Ltd. 0371-55932928 18937192232 1282296214@qq.com China 496 55
Supplier Advantage
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
InvivoChem 		58
Nanjing Doge Biomedical Technology Co., Ltd 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Zhengzhou HSH Science & Technology Co., Ltd. 55

DCPIB Spectrum

DCPIB(82749-70-0)MS

82749-70-0(DCPIB)Related Search:

2,3-Dichloro-4-hydroxybenzaldehyde 6-CHLORO-1-INDANONE 96 7-CHLORO-1-INDANONE 2-CHLORO-4,5-DIMETHYLPHENOL 4-(3-CHLORO-PHENOXY)-BUTYRIC ACID
2'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2',3'-DICHLORO-2,2-DIMETHYLBUTYROPHENONE 2-PENTYL-1-INDANONE 1-(3-chloro-4-ethoxyphenyl)ethanone DCPIB
1-(3-CHLORO-4-PROPOXYPHENYL)-ETHANONE 3'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2'-CHLORO-2,2-DIMETHYLPROPIOPHENONE 2',3'-DICHLORO-2,2-DIMETHYLPROPIOPHENONE 2,2-DIMETHYL-4'-METHOXYBUTYROPHENONE
4-(4-ACETYL-PHENOXY)-BUTYRIC ACID 1-(4-methoxyphenyl)-2,2-dimethyl-propan-1-one 3'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

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DCPIB 4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID 4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]- Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO 4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid 4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid 82749-70-0 Chloride channel