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NF 023

CAS No.
104869-31-0
Chemical Name:
NF 023
Synonyms
NF 023;NF023 hexasodium;NF 023 hydrate;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT;8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate;8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
CBNumber:
CB9220784
Molecular Formula:
C33H20N4Na6O19S6
Molecular Weight:
1106.86
MDL Number:
MFCD01074985
MOL File:
104869-31-0.mol
Last updated:2023-06-30 15:45:59

NF 023 Properties

storage temp. Desiccate at RT
solubility H2O: >20 mg/mL
form crystalline
color white
Water Solubility Soluble to 100 mM in water

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

NF 023 price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N8652 NF 023 hydrate ≥98% (HPLC), solid 104869-31-0 10mg $112.2 2024-03-01 Buy
Sigma-Aldrich N8652 NF 023 hydrate ≥98% (HPLC), solid 104869-31-0 50mg $602 2024-03-01 Buy
Sigma-Aldrich 480415 NF023 A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go/Gi group (EC?? ~ 300 nM). 10MG $332 2024-03-01 Buy
Tocris 1240 NF023 104869-31-0 10 $182 2021-12-16 Buy
Tocris 1240 NF023 104869-31-0 50 $767 2021-12-16 Buy
Product number Packaging Price Buy
N8652 10mg $112.2 Buy
N8652 50mg $602 Buy
480415 10MG $332 Buy
1240 10 $182 Buy
1240 50 $767 Buy

NF 023 Chemical Properties,Uses,Production

Uses

NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist.

Biological Activity

A subtype-selective, competitive and reversible P2X 1 receptor antagonist. Displays IC 50 values of 0.21, 28.9, > 50 and > 100 μ M for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α -subunit of G o/i (EC 50 ~? 300 nM).

Biochem/physiol Actions

NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.

storage

Desiccate at RT

NF 023 Preparation Products And Raw materials

Raw materials

Preparation Products

NF 023 Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 18521732826; market@aladdin-e.com China 25004 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Chunchuang (Wuhan) Technology Co., Ltd 15342225168 yutianchun2007@126.com China 10473 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44894 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
NF 023 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT 8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate 8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt 8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt NF 023 hydrate 8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt NF023 hexasodium 104869-31-0 C35H20N4Na6O21S6 C35H20N4O21S66Na BioChemical Cell Signaling and Neuroscience Cell Biology Ion Channels Ligand-Gated Ion Channels P2X Receptor Modulators Purinergics P2 receptor