MMP-2/MMP-9 INHIBITOR IV
- CAS No.
- 292605-14-2
- Chemical Name:
- MMP-2/MMP-9 INHIBITOR IV
- Synonyms
- CS-860;SB-3CT;SB−MMP-2/MMP-9 INHIBITOR IV;MMP-2/MMP-9 INHIBITITOR IV;[[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane;2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane;Thiirane, [[(4-phenoxyphenyl)sulfonyl]methyl]-;Thiirane, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-;SB-3CT (This product is only available in Japan.)
- CBNumber:
- CB9223336
- Molecular Formula:
- C15H14O3S2
- Molecular Weight:
- 306.4
- MDL Number:
- MFCD09836266
- MOL File:
- 292605-14-2.mol
- MSDS File:
- SDS
MMP-2/MMP-9 INHIBITOR IV price More Price(40)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S1326 | SB?3CT ≥98% (HPLC), powder | 292605-14-2 | 5mg | $354 | 2024-03-01 | Buy |
Sigma-Aldrich | 444274 | MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem | 292605-14-2 | 500μg | $216 | 2024-03-01 | Buy |
Cayman Chemical | 16337 | SB-3CT ≥95% | 292605-14-2 | 500μg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 16337 | SB-3CT ≥95% | 292605-14-2 | 1mg | $62 | 2024-03-01 | Buy |
Sigma-Aldrich | S1326 | SB?3CT ≥98% (HPLC), powder | 292605-14-2 | 25mg | $1430 | 2024-03-01 | Buy |
MMP-2/MMP-9 INHIBITOR IV Chemical Properties,Uses,Production
Uses
SB 3CT is a selective and potent gelatinase inhibitor which may be used for the treatment of brain metastasis.
Uses
SB?3CT has been used as irreversible inhibitor of matrix metallopeptidase 9 (MMP9) in cell cultures to exclude reciprocal regulation.
Definition
ChEBI: 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane is an aromatic ether.
Biochem/physiol Actions
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. SB-3CT exhibits a covalent mechanism based behavior in inhibition of MMP-2 and MMP-9. This inhibitor appears to have similarity to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. SB-3CT has been shown to directly bind to the zinc in the catalytic site of MMP-2. SB-3CT does not affect the activities of MMP-1 (Ki = 206 μM) MMP-3 (Ki = 15 μM), or MMP-7 (Ki = 96 μM).
storage
Store at -20°C
MMP-2/MMP-9 INHIBITOR IV Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from MMP-2/MMP-9 INHIBITOR IV manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-02 | 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane
292605-14-2
|
US $1.00 / KG | 1KG | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
- 2-[(4-phenoxyphenyl)sulfonylmethyl]thiirane
292605-14-2
- US $1.00 / KG
- Min98% HPLC
- Career Henan Chemical Co