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Sodium gluconate

Uses Preparation Use Restriction Content Analysis
Sodium gluconate
Sodium gluconate structure
CAS No.
527-07-1
Chemical Name:
Sodium gluconate
Synonyms
glonsen;pasexon100t;BVD Addicrete;Sunmorl N 60S;Disparlight DV;Developer,partB;Natriumgluconat;gluconatodisodio;SODIUM GLUCONATE;SOIDUMD-GLUCONATE
CBNumber:
CB9229989
Molecular Formula:
C6H13NaO7
Formula Weight:
220.15
MOL File:
527-07-1.mol

Sodium gluconate Properties

Melting point:
206 °C (dec.)(lit.)
alpha 
[α]D20 +11~+13° (c=10, H2O)
storage temp. 
Store below +30°C.
solubility 
H2O: 0.1 g/mL, clear
form 
Crystalline Powder
color 
White to light beige
PH
7.0-8.0 (100g/l, H2O, 20℃)
Water Solubility 
Very soluble in water; sparingly soluble in alcohol; insoluble in ether.
Merck 
14,4456
BRN 
3919651
Stability:
Stable. Incompatible with strong oxidizing agents.
Substances Added to Food (formerly EAFUS)
SODIUM GLUCONATE
SCOGS (Select Committee on GRAS Substances)
Sodium gluconate
CAS DataBase Reference
527-07-1(CAS DataBase Reference)
FDA 21 CFR
182.6757; 582.6757
EWG's Food Scores
1
FDA UNII
R6Q3791S76
EPA Substance Registry System
Sodium gluconate (527-07-1)
SAFETY
  • Risk and Safety Statements
Safety Statements  24/25
WGK Germany  1
RTECS  LZ5235000
Autoignition Temperature >200 °C
TSCA  Yes
HS Code  29181600
Toxicity LD50 orally in Rabbit: > 2000 mg/kg

Sodium gluconate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.22058 Gluconic acid sodium salt for synthesis 100 g $19.15 2021-03-22 Buy
Sigma-Aldrich 8.22058 Gluconic acid sodium salt for synthesis 1 kg $27.1 2021-03-22 Buy
Sigma-Aldrich G9005 D-Gluconic acid sodium salt ≥99% 527-07-1 1kg $47.9 2021-03-22 Buy
Sigma-Aldrich 8.22058 Gluconic acid sodium salt for synthesis 2.5 kg $49.58 2021-03-22 Buy
Sigma-Aldrich 64188 D-Gluconic acid sodium salt certified reference material, TraceCERT 527-07-1 100mg $100 2021-03-22 Buy

Sodium gluconate Chemical Properties,Uses,Production

Uses

Preparation

The calcium gluconate is added into the reaction kettle. Add sulfuric acid aqueous solution while stirring. After mixing for one hour, let it stand for a while and then get it filtered. The filter residue is CaSO4 and gets it removed. The filtrate is added into the neutralization kettle, and a proper amount of Na2CO3 aqueous solution is added to neutralize it. Finally get it through concentration, filtration and drying. Check the finished products with proper packaging.

Use Restriction

Within the limit of GMP(FDA,§182.6757,2000).

Content Analysis

Weigh the sample of about 750mg. Put it into a dry conical flask of 200ml. Add glacial acetic acid of 75 ml to it. Heat the mixture on the heating plate and after it dissolves, get it cooled. Add several drops of quinaldine red solution (TS-203), use glacial acetic acid solution of 0.1mol/L perchloric acid to titrate the mixture until it gets colorless through microburet of 10ml. Perchloric acid per ml0.1mol/L is equivalent to sodium gluconate (C6H11NaO7) 21.81mg.

Chemical Properties

white or off-white granular powder

Originator

Sodium gluconate,JUNGBUNZLAUER INC.

Uses

electrolyte replenisher

Definition

ChEBI: An organic sodium salt having D-gluconate as the counterion.

Manufacturing Process

D-Gluconic acid was prepared by fermentation of glucose with Aspergillus niger CCM 8004 at 30°C. The fermentation medium contained 150 g/dm-3 glucose, 0.59 g/dm-3 ammonium sulfate, 0.25 g/dm-3 potassium chloride, 0.25 g/dm-3 potassium dihydrophosphate, 0.25 g/dm-3 MgSO4·7H2O, 1.0 g/dm-3 Ca(NO3)2·4H2O, and 1.5 g/dm-3 of a 50% corn-steep liquor. The pH of the culture was maintained at the value of 6.5 during the growth phase and 5.5 (maximum glucose oxidase activity) during the production phase by addition of 11.7 M sodium hydroxide solution. Gluconic acid concentration was determined by HPLC analysis. By neutralization of D-gluconic acid with sodium hydroxide was obtained monosodium D-gluconate.

Therapeutic Function

Electrolyte replenisher

Safety Profile

Low toxicity by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes

Purification Methods

Crystallise it from a small volume of H2O (solubility is 59g/100mL at 25o), or dissolve it in H2O and add EtOH since it is sparingly soluble in EtOH. It is insoluble in Et2O. It forms a Cu complex in alkaline solution and a complex with Fe in neutral solution. [cf p 639, Sawyer & Bagger J Am Chem Soc 81 5302 1959, Beilstein 3 I 188.]

Sodium gluconate Preparation Products And Raw materials

Raw materials

Preparation Products


Sodium gluconate Suppliers

Global( 473)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20010 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22608 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2813 55
Hebei Chisure Biotechnology Co.LTD
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career henan chemical co
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Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8406 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 whatapp+8619930503282
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Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 914 58

View Lastest Price from Sodium gluconate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-04-25 Gluconic acid sodium salt
527-07-1
US $100.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biological Technology Co., Ltd
2021-04-20 Sodium Gluconate
527-07-1
US $50.00 / KG 1Kg/Bag 99.99% 20 tons/month Wuhan Monad Medicine Tech Co.,LTD
2020-01-13 Sodium gluconate
527-07-1
US $0.00-0.00 / KG 1KG 99.0%+ 100 tons Shaanxi Dideu Medichem Co. Ltd

Sodium gluconate Spectrum


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