Cefmetazole | 56796-20-4

Cefmetazole Properties

Melting point	163-165?C
Density	1.4380 (rough estimate)
refractive index	1.7400 (estimate)
storage temp.	2-8°C
solubility	Methanol (Slightly, Heated)
form	Solid
pka	2.65±0.50(Predicted)
color	White
Water Solubility	Soluble in water
CAS DataBase Reference	56796-20-4(CAS DataBase Reference)
FDA UNII	3J962UJT8H
ATC code	J01DC09

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Warning

Hazard statements

H315-H317-H319-H334-H335

Precautionary statements

P261-P280a-P284-P305+P351+P338-P405-P501a

Hazard Codes

Xn

Risk Statements

36/37/38-42/43

Safety Statements

26-36

WGK Germany

2

RTECS

XI0372200

HS Code

2941906000

NFPA 704

	0
2		0

Cefmetazole price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	1097782	Cefmetazole United States Pharmacopeia (USP) Reference Standard	56796-20-4	200MG	$420	2024-03-01	Buy
Alfa Aesar	J66791	Cefmetazole	56796-20-4	5g	$406	2024-03-01	Buy
Alfa Aesar	J66791	Cefmetazole	56796-20-4	1g	$89.1	2021-12-16	Buy
Cayman Chemical	30269	Cefmetazole	56796-20-4	10mg	$121	2024-03-01	Buy
Cayman Chemical	30269	Cefmetazole	56796-20-4	100mg	$961	2024-03-01	Buy

Product number	Packaging	Price	Buy
1097782	200MG	$420	Buy
J66791	5g	$406	Buy
J66791	1g	$89.1	Buy
30269	10mg	$121	Buy
30269	100mg	$961	Buy

Cefmetazole Chemical Properties,Uses,Production

Description

Cefmetazole is a cephamycin with a nonaromatic side chain at C-7. In addition to a fairly characteristic second-generation cephalosporin antimicrobial spectrum, it possess fairly significant anti-antiaerobic activity. The ejection of its C-3 side chain leads to alcohol intolerance of the disulfuram type and prolonged clotting times.

General Description

Cefmetazole was synthesized by Sankyo Co. in 1976starting with a biosynthetic cephamycin. It shows excellent activity against Serratia and Proteus, against which cefazolin is not active, and it has stronger activity than cefoxitin, another derivative of cephamycin. Cefmetazole is active against anaerobes and resistant to β-lactamase, but it is not active against Pseudomonas aeruginosa.

Chemical Properties

White Solid

Uses

A broad spectrum second generation cephalosporin antibiotic

Uses

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial.

Definition

ChEBI: A cephalosporin antibiotic containg an N1-methyltetrazol-5-ylthiomethyl side-chain at C-3 of the parent cephem bicyclic structure.

Antimicrobial activity

It is active against Pr. mirabilis, Pr. vulgaris, Morganella morganii, Yersinia spp.and most anaerobes. S. marcescens is moderately susceptible, but Ps. aeruginosa and E. faecalis are resistant. It is active against Mycobacterium fortuitum and some strains of M. chelonei. It is resistant to a wide range of β-lactamases.
The serum concentration at the end of a 1 g intravenous infusion is around 77 mg/L. Plasma protein binding is 68%. It is principally excreted in the urine with a plasma half-life of c. 1.3 h; 70% is recovered over the first 6 h. In patients whose creatinine clearance is less than 10 mL/min, plasma levels are elevated and the plasma half-life is increased to around 15 h.
Side effects associated with the methylthiotetrazole group at position C-3 have been reported. Uses are similar to those of cefoxitin, but it is not widely available.

Cefmetazole Preparation Products And Raw materials

Raw materials

Preparation Products

Cefmetazole Suppliers

Global( 147)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+86-13474506593 +86-13474506593	sarah@tnjone.com	China	794	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	8349	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58
TargetMol Chemicals Inc.	58

View Lastest Price from Cefmetazole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-10	Cefmetazole 56796-20-4	US $0.00-0.00 / mg	10mg	90%+	10g	Guangzhou PI PI BIOTECH INC
2024-04-09	Cefmetazole 56796-20-4	US $0.00 / Kg	1Kg	99%	10kg	Shaanxi TNJONE Pharmaceutical Co., Ltd
2023-09-01	Cefmetazole 56796-20-4	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd

Cefmetazole
56796-20-4
US $0.00-0.00 / mg
90%+
Guangzhou PI PI BIOTECH INC

Cefmetazole
56796-20-4
US $0.00 / Kg
99%
Shaanxi TNJONE Pharmaceutical Co., Ltd

Cefmetazole
56796-20-4
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

56796-20-4(Cefmetazole)Related Search:

Bensulfuron methyl Methyl acrylate Acetyl coenzyme A sodium salt Kresoxim-methyl Methylparaben

Acetaminophen Cefotetan 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-quinolinium inner salt Cefozopran Ceftiofur sodium

Methyl Parathion-methyl CEFMETAZOLE ACID Methyl bromide Cefmetazole-Na,Sodium cefmetazole,Cefmetazole sodium

7-TMCA 3-AZETIDINOL 1-METHYL-3-AZETIDINOL

1of4

(6R,7S)-7-[[2-[(CyanoMethyl)thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl -1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid (6r 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((((cyanomethyl)thio)a Cefmetazole, 97-103% CEFMETAZOLE SODIUM SALT Cefmetazole Cefatrixine 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7S)- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R-cis)- SKF 83088 U 72791 U 72791a (6R-cis)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R)-7α-[2-(Cyanomethylthio)acetylamino]-7β-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7S)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CMZ Cefmetazole (200 mg)G0E2600.988mg/mg(ai) Cefmetazole (200 mg) Ferrous Sulfate (2 x 1 g) 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7S)- (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Cefmetazole USP/EP/BP CEFMETAZOLE ACID 56796-20-4 Cefmetazole (1097782) Cefmetazolo Cefmetazolum cs1170 (6R,7S)-7-(2-((Cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid (Cefmetazole Impurity) Cefmetazole, free acid 56796-20-4 C14H15N7O4S3 Antibiotics A-F Antibiotics A to Z Antibiotics BioChemical Pharmaceuticals Sulfur & Selenium Compounds Pharmaceutical intermediate Medicine intermediate Chiral Reagents Heterocycles Intermediates & Fine Chemicals