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Abstract Extraction Natural occurance Synthetic method Pharmacological effects
Chemical Name:
HYPERIN;hyperasid;HYPEROSID;hyperozide;HYPEROSIDE;HYPEROSIDE(P);HYPEROSIDE hplc;Hyperoside (50 mg);Hyperoside, Hyperin;HYPEROSIDE WITH HPLC
Molecular Formula:
Formula Weight:
MOL File:

Hyperoside Properties

Melting point:
storage temp. 
-20°C Freezer, Under Inert Atmosphere
CAS DataBase Reference
482-36-0(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22-40
Safety Statements  22-45-36-24/25
WGK Germany  3
RTECS  DJ3009200
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Hyperoside price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 00180585 Hyperoside primary reference standard 482-36-0 25mg $416 2018-11-13 Buy
Sigma-Aldrich 1335202 Hyperoside United States Pharmacopeia (USP) Reference Standard 482-36-0 50mg $1670 2018-11-13 Buy
Cayman Chemical 18648 Quercetin 3-D-galactoside ≥98% 482-36-0 1mg $25 2018-11-13 Buy
Cayman Chemical 18648 Quercetin 3-D-galactoside ≥98% 482-36-0 5mg $113 2018-11-13 Buy
Sigma-Aldrich 83388 Quercetin 3-D-galactoside ≥97.0% (HPLC) 482-36-0 1mg $106 2018-11-13 Buy

Hyperoside Chemical Properties,Uses,Production


Hyperoside is an active ingredient of traditional Chinese medicine extracted from Hypericum perforatum. Modern pharmacological studies have shown that it has a strong analgesic effect, and it could protect the heart, brain, liver, anti-myocardial hypoxia damage and protect cerebral ischemic injury. In recent years, the development of hypericin for the treatment of depression, hepatitis B and other diseases has become a hotspot both in domestic and foreign research.


1.  According to Zhongcheng Ke and others, the volume fraction of ethanol, the ratio of material to liquid and the extraction time were independent variables, the extraction rate of hyperoside was the dependent variable, Through the regression of the independent variables and the dependent variables, extraction technology is screened by response surface method predict the best extraction conditions. The results showed that the extraction process was 11.0 times the amount of 77.6% ethanol, and twice with each for 2.7 h.
2.  According to Zhuoheng Li and others, taking ethanol concentration, ethanol addition factor, extraction temperature and extraction times as the influencing factors, using the extraction rate of hyperoside as an index, the orthogonal experiment was used to optimize the optimum conditions of hyperoside ethanol extraction. The optimum extraction process is 20 times the amount of 60% ethanol, and 4 times at 90 ℃ with each for 2 h. The method is simple, accurate and reproducible.

Natural occurance

Hyperoside is an important natural substance extracted from the dried flowers of the mallow leaves. It is a pale yellow needle-like crystal, and soluble in ethanol, methanol, acetone and pyridine, and stable usually. It could react with hydrochloric acid-magnesium powder to generate cherry red material.
Hyperoside is a flavonol glycoside compound. Hyperoside also has a strong role in inhibiting oogidity reductase, and may be beneficial to the prevention of diabetic cataracts.

Synthetic method

Hyperoside is a natural extract and can also be synthesized now. For the synthesis process, re-read the relevant literature to add. Rutin was used as raw material to obtain hyperoside by benzylation, acid hydrolysis, glycoside condensation through phase transfer catalyzing, deacetylation and debenzylation.
synthetic route of hyperoside

Pharmacological effects

Chemical Properties

Yellow Solid


A major flavonoid in apple peels; a bioactive constituent of apple peels


ChEBI: A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity.

Hyperoside Preparation Products And Raw materials

Raw materials

Preparation Products

Hyperoside Suppliers

Global( 182)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3217 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 CHINA 894 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897 CHINA 2238 58
career henan chemical co
+86-371-86658258 CHINA 19990 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 CHINA 3624 58
Baoji Herbest Bio-Tech Co.,Ltd. +86-917-8888998
+86-917-3313696 China 376 58
Shanghai BeiZhuo Biotech Co., Ltd. 021-61119791/13386096464
021-50190009 China 3973 50
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 QQ:2851167785
028-81705658 China 2701 56
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76

View Lastest Price from Hyperoside manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Hyperoside
US $2.00 / KG 1KG 98% 1 ton career henan chemical co

Hyperoside Spectrum

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