ChemicalBook >> CAS DataBase List >>1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-

CAS No.
446292-08-6
Chemical Name:
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
Synonyms
(S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione;Rivaroxaban-5;Rivaroxaban G;Rivaroxaban ImpVI;2-Amino-13-picoline;Rivaroxaban Intermediate5;Rivaroxaban EP Impurity G;Rivaroxaban Impurities365;RivaroxabanInterMediates-01;Rivaroxaban Phthalimido Impurity
CBNumber:
CB92468058
Molecular Formula:
C22H19N3O6
Molecular Weight:
421.4
MDL Number:
MFCD11977665
MOL File:
446292-08-6.mol
MSDS File:
SDS
Modify Date:2022-11-09 15:39:33

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Properties

Melting point 213-215°C
Boiling point 702.9±55.0 °C(Predicted)
Density 1.465±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 0.99±0.20(Predicted)
form Solid
color White to Off-White
Water Solubility 12mg/L at 20℃
LogP -0.2 at 25℃

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P385850 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone 446292-08-6 25mg $120 2021-12-16 Buy
TRC P385850 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone 446292-08-6 50mg $155 2021-12-16 Buy
TRC P385850 4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone 446292-08-6 100mg $185 2021-12-16 Buy
AK Scientific Z6156 1H-Isoindole-1,3(2H)-dione,2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- 446292-08-6 1g $143 2021-12-16 Buy
Matrix Scientific 092112 (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)isoindoline-1,3-dione 95+% 446292-08-6 250mg $439 2021-12-16 Buy
Product number Packaging Price Buy
P385850 25mg $120 Buy
P385850 50mg $155 Buy
P385850 100mg $185 Buy
Z6156 1g $143 Buy
092112 250mg $439 Buy

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Chemical Properties,Uses,Production

Uses

1H-isoindole-1,3(2H)-dione, 2-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]- is an important intermediate for the synthesis of rivaroxaban, which is an anticoagulant and the first orally active direct factor Xa inhibitor.

Chemical Properties

White Solid

Uses

Rivaroxaban intermediate.

Flammability and Explosibility

Nonflammable

1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 233)Suppliers
Supplier Tel Email Country ProdList Advantage
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29789 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886 info@dakenchem.com China 17337 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21975 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714 fandachem@gmail.com China 9361 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED
21-51619050 ivan@atkchemical.com China 31281 60
Anqing Chico Pharmaceutical Co., Ltd.
15380796838 chloewu@chicopharm.cn CHINA 341 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29922 58

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Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-ISOindole-1,3(2H) -Dione, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHolinyl)PHENYL] -5-OXAZolidinyl]METHYL]- pictures 2022-10-07 1H-ISOindole-1,3(2H) -Dione, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHolinyl)PHENYL] -5-OXAZolidinyl]METHYL]-
446292-08-6
US $30.00-28.00 / Kg 1Kg 99.0% up 50 tons per month Xinxiang Hongqi District Houyuan Trading Co.,Ltd
(R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione pictures 2022-09-20 (R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione
446292-08-6
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
	1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- pictures 2019-07-06 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-
446292-08-6
US $2.00 / KG 10KG 99% 20kg Career Henan Chemical Co
1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- 2-({(5S)-2-oxo-3-[4-(3-oxoMorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}Methyl)-1H-isoindole-1,3(2H)-dione RivaroxabanInterMediates-01 4-[4-[(5S)-5-PhthaliMidoMethyl-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione Rivaroxaban Intermediate5 Rivaroxaban Phthalimido Impurity 2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl} 2 - [[(5S) -2- oxo-3- [4- (3-oxo - (morpholin-4-yl)) phenyl] -5-oxazolidinyl] methyl] lH- isoindole -1,3 (2H) - dione 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- (R)-2-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione Rivaroxaban ImpVI Rivaroxaban impurity 4/2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione 2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dion Rivaroxaban G (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)isoindoline-1,3-dione (Rivaroxaban) Rivaroxaban EP Impurity G 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]-1H-ISOINDOLE-1,3(2H)-DIONE CAS: 446292-08-6 Rivaroxaban PTH Imp/Rivaroxaban EP Impurity G 2-Amino-13-picoline 2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazoli... Rivaroxaban Impurities365 TIANFUCHEM--446292-08-6---1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Rivaroxaban EP Impurity GQ: What is Rivaroxaban EP Impurity G Q: What is the CAS Number of Rivaroxaban EP Impurity G Q: What is the storage condition of Rivaroxaban EP Impurity G Q: What are the applications of Rivaroxaban EP Impurity G (S)-2-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)isoindoline-1,3-dione Rivaroxaban-5 (S)-2-((2-Oxo-3-(4-(3-oxomorpholino)phenyl)oxazoli 446292-08-6 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Intermediate of Rivaroxaban