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10-trans-Atorvastatin Acetonide tert-Butyl Ester

CAS No.
1105067-90-0
Chemical Name:
10-trans-Atorvastatin Acetonide tert-Butyl Ester
Synonyms
Atorvastatin calcium-26;Atorvastatin L1 Diastereomer;Atorvastatin calcium impurity 39;(3S,5R)-Atorvastatin Acetonide tert-Butyl Ester;10-trans-Atorvastatin Acetonide tert-Butyl Ester;Atorvastatin Protected Diol Diastereomer Impurity;Atorvastatin Acetonide t-Butyl Ester (4S, 6R)-Isomer;Atorvastatin L1 Diastereomer (Atorvastatin Impurity 17);tert-butyl 2-[(4S,6R)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate;tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl -4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan -4-yl)acetate
CBNumber:
CB92507698
Molecular Formula:
C40H47FN2O5
Molecular Weight:
654.81
MDL Number:
MFCD12031520
MOL File:
1105067-90-0.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

10-trans-Atorvastatin Acetonide tert-Butyl Ester Properties

Melting point 142-143°C
Boiling point 678.0±55.0 °C(Predicted)
Density 1.14±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Dichloromethane
pka 13.57±0.70(Predicted)
form Solid
color Off-White

10-trans-Atorvastatin Acetonide tert-Butyl Ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A791805 10-trans-AtorvastatinAcetonidetert-ButylEster 1105067-90-0 2.5mg $155 2021-12-16 Buy
American Custom Chemicals Corporation CHM0034251 10-TRANS- ATORVASTATIN ACETONIDE TERT-BUTYL ESTER 95.00% 1105067-90-0 2.5MG $704 2021-12-16 Buy
American Custom Chemicals Corporation CHM0034251 10-TRANS- ATORVASTATIN ACETONIDE TERT-BUTYL ESTER 95.00% 1105067-90-0 25MG $1871.1 2021-12-16 Buy
Product number Packaging Price Buy
A791805 2.5mg $155 Buy
CHM0034251 2.5MG $704 Buy
CHM0034251 25MG $1871.1 Buy

10-trans-Atorvastatin Acetonide tert-Butyl Ester Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of Atorvastatin 10-Trans (Atorvastatin Impurity AT10)

1105067-89-7
125971-96-2
1105067-90-0
125971-95-1
Synthesis of 10-trans-Atorvastatin Acetonide tert-Butyl Ester from (4S,trans)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate and 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
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10-trans-Atorvastatin Acetonide tert-Butyl Ester (4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester (3S,5R)-Atorvastatin Acetonide tert-Butyl Ester Atorvastatin Acetonide t-Butyl Ester (4S, 6R)-Isomer tert-butyl 2-((4S,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl -4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan -4-yl)acetate tert-butyl 2-[(4S,6R)-6-[2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate Atorvastatin impurity 25/10-trans-Atorvastatin Acetonide tert-Butyl Ester/(4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester Atorvastatin calcium-26 (4S,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenyl amino) carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid t-butyl ester 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S,6R)- Atorvastatin Protected Diol Diastereomer Impurity Atorvastatin L1 Diastereomer Atorvastatin L1 Diastereomer (Atorvastatin Impurity 17) Atorvastatin calcium impurity 39 1105067-90-0 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals