Pitavastatin-d5 Lactone

CAS No.
Chemical Name:
Pitavastatin-d5 Lactone
Synonyms
NK 104-d5;P 872441-d5;Nisvastatin-d5;NK 104-d5 (lactone);Pitavastatin-d5 Lactone;(4R,6S)-6-[(1E)-2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one;[4R-[4α,6β(E)]]-6-[2-[2-(Cyclopropyl-d5)-4- (4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one
CBNumber:
CB92545580
Molecular Formula:
C25H22FNO3
Molecular Weight:
403.4454832
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Pitavastatin-d5 Lactone Properties

Melting point 72-75°C
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
color White to Pale Yellow
Stability Hygroscopic

Pitavastatin-d5 Lactone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P531022 Pitavastatin-d5Lactone 1mg $655 2021-12-16 Buy
Usbiological 019819 Pitavastatin-d5 Lactone 1mg $1097 2021-12-16 Buy
TRC P531022 Pitavastatin-d5Lactone 5mg $3090 2021-12-16 Buy
Product number Packaging Price Buy
P531022 1mg $655 Buy
019819 1mg $1097 Buy
P531022 5mg $3090 Buy

Pitavastatin-d5 Lactone Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

A labelled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells

Uses

A labelled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells.

Pitavastatin-d5 Lactone Preparation Products And Raw materials

Raw materials

Preparation Products

Pitavastatin-d5 Lactone Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Pitavastatin-d5 Lactone (4R,6S)-6-[(1E)-2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one [4R-[4α,6β(E)]]-6-[2-[2-(Cyclopropyl-d5)-4- (4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one Nisvastatin-d5 NK 104-d5 NK 104-d5 (lactone) P 872441-d5 C25H17D5FNO3 Aromatics Chiral Reagents Inhibitors Intermediates & Fine Chemicals Isotope Labelled Compounds Metabolites & Impurities Pharmaceuticals