ChemicalBook >> CAS DataBase List >>CTOP

CTOP

CAS No.
103429-31-8
Chemical Name:
CTOP
Synonyms
NTB;CTOP;NALTRIBEN;threoninamide;CYS2,TYR3,ORN5,PEN7-AMIDE;M.W. 1062.26 C50H67N11O11S2;(Tyr3,Orn5,Pen7)-Octreotate amide;Cys2, Tyr3, Orn5, Pen7 amide - CTOP;DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL;D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2
CBNumber:
CB9260913
Molecular Formula:
C50H67N11O11S2
Molecular Weight:
1062.26
MDL Number:
MFCD00076708
MOL File:
103429-31-8.mol
Last updated:2023-06-30 15:45:59

CTOP Properties

Boiling point 1491.2±65.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
RTECS XO8578200
storage temp. -20°C
form Powder
pka 9.90±0.15(Predicted)
Water Solubility Soluble to 1 mg/ml in water
FDA UNII G5H9PK5HEK

SAFETY

Risk and Safety Statements

WGK Germany  3

CTOP price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P5296 CTOP ≥97% (HPLC) 103429-31-8 1mg $274 2024-03-01 Buy
Alfa Aesar J66263 CTOP 103429-31-8 1mg $122 2021-12-16 Buy
Alfa Aesar J66263 CTOP 103429-31-8 5mg $441 2021-12-16 Buy
Tocris 1578 CTOP 103429-31-8 1 $195 2021-12-16 Buy
TRC C800010 CTOP 103429-31-8 1mg $195 2021-12-16 Buy
Product number Packaging Price Buy
P5296 1mg $274 Buy
J66263 1mg $122 Buy
J66263 5mg $441 Buy
1578 1 $195 Buy
C800010 1mg $195 Buy

CTOP Chemical Properties,Uses,Production

Uses

CTOP is a μ-opioid receptor antagonist which has been shown to regulate behaviour and expression in rats. An endogenous opioid peptide which may also be used in the treatment of pain through improved morphine tolerance via blocking of mTOR.

Uses

CTOP has been used:

  • to study the anxiogenic effects induced by CTOP in mice and rat.
  • to study the effect of μ-opioid antagonist, CTOP on the bovine milk-derived LF (BLF)-induced analgesia.
  • to determine whether μ-opioid receptors act cooperatively with 5-hydroxytryptamine (5-HT1A) receptors to regulate the behaviors generated in the elevated T-maze (ETM).

General Description

D-Pen-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) is a selective cyclic μ-opioid receptor antagonist.

Biochem/physiol Actions

Selective ligand for μ-opioid receptors.

storage

Store at -20°C

CTOP Preparation Products And Raw materials

Raw materials

Preparation Products

CTOP Suppliers

Global( 92)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213 info@longyupharma.com China 2531 58
Cellmano Biotech Limited
0551-65326643 18156095617 info@cellmano.com China 999 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58

View Lastest Price from CTOP manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CTOP pictures 2020-02-12 CTOP
103429-31-8
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co
  • CTOP pictures
  • CTOP
    103429-31-8
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co
threoninamide NALTRIBEN NTB D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR AMIDE D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL CTOP CYS2,TYR3,ORN5,PEN7-AMIDE [CYS2, TYR3, ORN5, PEN7]-SOMATOSTATIN 14 (7-14), AMIDE H-D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 H-D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 (DISULFIDE BRIDGE: 2-7) FCYW(ORN)T(PEN)T-NH2 (DISULFIDE BRIDGE: 2-7) phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2, (Disulfide bond between Cys2 and Pen7) M.W. 1062.26 C50H67N11O11S2 D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Orn-L-Thr-3-Mercapto(1)-L-Val-L-Thr-NH2 D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Orn-L-Thr-L-Pen(1)-L-Thr-NH2 [Cys2, Tyr3, Orn5, Pen7-amide]-Somatostatin 14 (7-14) Cys2, Tyr3, Orn5, Pen7 amide - CTOP CTOP, (Tyr3,Orn5,Pen7)-Octreotate aMide (Tyr3,Orn5,Pen7)-Octreotate amide phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine) H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Disulfide bond) L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-, cyclic (2→7)-disulfide Cys2, Tyr3, Orn5, Pen7-NH2]-Somatostatin14(7-14) 103429-31-8 C50H67N11O11S2 Opioid Peptides Other Opioid Peptides Peptides BioChemical Biochemicals and Reagents Amino Acids and Peptides peptide Neuropeptides Opioid Peptides Other Opioid Peptides Other Opioid PeptidesPeptides for Cell Biology Opioid receptor and opioid-like receptor