GS9620
- CAS No.
- 1228585-88-3
- Chemical Name:
- GS9620
- Synonyms
- Gs-20;GS9620;CS-925;GS 9620;GS-9620;Vesatolimod;GS9620, >=98%;GS 9620; GS9620;GS-9620(Vesatolimod);Vesatolimod GS-9620
- CBNumber:
- CB92666623
- Molecular Formula:
- C22H30N6O2
- Molecular Weight:
- 410.51
- MDL Number:
- MFCD25372045
- MOL File:
- 1228585-88-3.mol
- MSDS File:
- SDS
| Density | 1.247±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| solubility | Soluble in DMSO (10 mg/ml) |
| pka | 10.34±0.20(Predicted) |
| form | solid |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| FDA UNII | O8M467C50G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
GS9620 price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19628 | GS-9620 ≥98% | 1228585-88-3 | 5mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 19628 | GS-9620 ≥98% | 1228585-88-3 | 10mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 19628 | GS-9620 ≥98% | 1228585-88-3 | 25mg | $180 | 2024-03-01 | Buy |
| Cayman Chemical | 19628 | GS-9620 ≥98% | 1228585-88-3 | 100mg | $477 | 2024-03-01 | Buy |
| ApexBio Technology | A3444 | GS-9620 | 1228585-88-3 | 50mg | $700 | 2021-12-16 | Buy |
GS9620 Chemical Properties,Uses,Production
Description
GS-9620 is a potent and selective oral Toll-like receptor 7 (TLR7) agonist that directly activates plasmacytoid dendritic cells (pDCs). GS-9620 suppressed hepatitis B virus (HBV) in animal models of chronic infection and transiently activated HIV expressionex vivoin latently-infected peripheral blood mononuclear cells (PBMCs) from virally suppressed patients. Currently, GS-9620 is under clinical evaluation for treating chronic HBV infection and for reducing latent reservoirs in virally-suppressed HIV-infected patients.
target
TLR-7
References
Lopatin, U, et al. "Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist." Antiviral Therapy18.3(2013):409-18.
Gane, E. J., et al. "The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection." Journal of Hepatology63.2(2015):320.
Lanford, Robert E., et al. "GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees." Gastroenterology 144.7(2013):1508.
GS9620 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
View Lastest Price from GS9620 manufacturers
1228585-88-3(GS9620)Related Search:
1of4